Effects of inspiratory muscle training on dynamic hyperinflation in patients with COPD
Open accessAbstract
Dynamic hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT). The aim of the study was to analyze the effects of IMT on exercise capacity, dyspnea, and inspiratory fraction (IF) during exercise in patients with COPD. Daily inspiratory muscle strength and endurance training was performed for 8 weeks in 10 patients with COPD GOLD II and III. Ten patients with COPD II and III served as a control group. Maximal inspiratory pressure (Pimax) and endurance time during resistive breathing maneuvers (tlim) served as parameter for inspiratory muscle capacity. Before and after training, the patients performed an incremental symptom limited exercise test to maximum and a constant load test on a cycle ergometer at 75% of the peak work rate obtained in the pretraining incremental test. ET was defined as the duration of loaded pedaling. Following IMT, there was a statistically significant increase in inspiratory muscle performance of the Pimax from 7.75 ± 0.47 to 9.15 ± 0.73 kPa (P < 0.01) and of tlim from 348 ± 54 to 467 ± 58 seconds (P < 0.01). A significant increase in IF, indicating decreased dynamic hyperinflation, was observed during both exercise tests. Further, the ratio of breathing frequency to minute ventilation (bf/V'(E)) decreased significantly, indicating an improved breathing pattern. A significant decrease in perception of dyspnea was also measured. Peak work rate during the incremental cycle ergometer test remained constant, while ET during the constant load test increased significantly from 597.1 ± 80.8 seconds at baseline to 733.6 ± 74.3 seconds (P < 0.01). No significant changes during either exercise tests were measured in the control group. The present study found that in patients with COPD, IMT results in improvement in performance, exercise capacity, sensation of dyspnea, and improvement in the IF prognostic factor.
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Positive effects of inspiratory muscle training on operational lung volumes and breathing patterns during exercise have so far only been demonstrated in a single study.
“Positive effects of inspiratory muscle training on operational lung volumes and breathing patterns during exercise have so far only been demonstrated in a single study.197”
From Pathogenesis of hyperinflation in chronic obstructive pulmonary disease (2014) · cites this paper as [197]
The Discussion (page not provided) reports improved breathing patterns during exercise, and the Abstract reports an increased inspiratory fraction, indicating reduced dynamic hyperinflation. The paper does not establish that this was the only study to demonstrate those effects. (LLM, conf=0.83)
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Cites
American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation
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Pathogenesis of hyperinflation in chronic obstructive pulmonary disease
Saey, Gagnon, P., Guenette, J., Langer, D., Laviolette, L., Mainguy, V., Maltais, F., & Ribeiro, F. (2014) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s38934 · Cited by 180 · see citing works
“during exercise have so far only been demonstrated in a single study.(197) More research into the mechanisms linking inspiratory muscle training to reduction of dyspnea during daily activities is warranted.”
- Authors
- Petrovic, M., Reiter, Wanke, Pohl, & Zipko
- Affiliations
- Klinik Hietzing (AT)
- Otto Wagner Hospital (AT)
- Corresponding author
- Petrovic, Milos
- Venue
- International Journal of Chronic Obstructive Pulmonary Disease
- Publisher
- Informa UK Limited
- Published
- 2012-11
- Volume
- 7
- Pages
- 797
- ISSN
- 1176-9106 (ISSN-L)
- 1178-2005
- PMC
- PMC3516469
- OpenAlex
- W1997185943
- Cited by
- 83
- References
- 3
- Citations by year
- 2026: 9 · 2025: 1 · 2024: 2 · 2023: 9 · 2022: 8 · 2021: 5 · 2020: 8 · 2019: 4 · 2018: 12 · 2017: 8 · 2016: 4 · 2015: 2 · 2014: 9 · 2013: 1
- FWCI
- 3.10
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of COPD (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- inspiratory muscle training, dynamic hyperinflation, chronic obstructive pulmonary disease, exercise capacity, dyspnea, maximal inspiratory pressure, inspiratory muscle endurance, breathing pattern, cycle ergometry
- MeSH terms
- Aged, Inhalation, Austria, Breathing Exercises, Dyspnea, Exercise Test, Female, Humans, Lung, Male, Middle Aged, Respiratory Function Tests, Respiratory Muscles, Time Factors, Work of Breathing, Treatment Outcome, Exercise Tolerance, Recovery of Function, Pulmonary Disease, Chronic Obstructive
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