Clinical manifestations and genetic influences in sulfonamide-induced hypersensitivity
Open accessAbstract
Drug hypersensitivity is an inflammatory or immune reaction induced by drugs. It can be fatal if not appropriately treated and cause the risk of long-term complications. Sulfonamides are classified as antimicrobial drugs with a broad spectrum effective for gram-positive and gram-negative bacteria. This antibacterial agent works by competitively inhibiting folic acid synthesis, which prevents the growth and proliferation of microorganisms. In its use as antibiotics, sulfonamides can also cause adverse reactions in specific individuals. It has been widely reported that sulfonamide antimicrobials cause hypersensitivity reactions mediated by IgE or T cells. This review identifies symptoms or signs that can appear, as well as genes associated with sulfonamide hypersensitivity reactions, as sulfonamide may cause hypersensitivity in the form of uveitis, skin rash, Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), parotitis, angioedema, drug reaction with eosinophilia and systemic symptoms (DRESS), and pruritus. In addition, several genes were found to be associated with sulfonamide hypersensitivity, including HLA-A29, HLA-B12, HLA-DR7, HLA-B44, and HLA A*11:01.
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Cites
(2005) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2005.03.057 · Cited by 4,396 · see citing works
Johansson, S. G. O., Bieber, T., Dahl, R., Friedmann, P. S., Lanier, B. Q., Lockey, R. F., Motala, C., Ortega Martell, J. A., Platts-Mills, T. A. E., Ring, J., et al. (2004) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2003.12.591 · Cited by 2,391 · see citing works
Bastuji‐Garin, S. (1993) · Archives of Dermatology · doi:10.1001/archderm.1993.01680220104023 · Cited by 1,630 · see citing works
Kardaun, S. H., Sekula, P., Valeyrie‐Allanore, L., Liss, Y., Chu, C., Creamer, D., Sidoroff, A., Naldi, L., Mockenhaupt, M., Roujeau, J., et al. (2013) · British Journal of Dermatology · doi:10.1111/bjd.12501 · Cited by 1,006 · see citing works
Clinical features and severity grading of anaphylaxis
Brown, S. G. A. (2004) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2004.04.029 · Cited by 999 · see citing works
Delayed Drug Hypersensitivity Reactions
Pichler, W. J. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-139-8-200310210-00012 · Cited by 737 · see citing works
Lonjou, C., Borot, N., Sekula, P., Ledger, N., Thomas, L., Halevy, S., Naldi, L., Bouwes-Bavinck, J.-N., Sidoroff, A., de Toma, C., et al. (2008) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e3282f3ef9c · Cited by 624 · see citing works
Epidemiology and risk factors for drug allergy
Thong, B. Y., & Tan, T. C. (2010) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2010.03774.x · Cited by 393 · see citing works
Disruption of HAUSP gene stabilizes p53.
Cummins, J. M., Rago, C., Kohli, M., Kinzler, K. W., Lengauer, C., & Vogelstein, B. (2004) · Nature · doi:10.1038/nature02501 · Cited by 379 · see citing works
Idiosyncratic Adverse Reactions to Antiepileptic Drugs
Zaccara, G., Franciotta, D. M., & Perucca, E. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2007.01041.x · Cited by 365 · see citing works
Identification and determination of metabolites and degradation products of sulfonamide antibiotics
García-Galán, M. J., Díaz‐Cruz, M. S., & Barceló, . (2008) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2008.10.001 · Cited by 357 · see citing works
Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Lerch, M., Mainetti, C., Beretta‐Piccoli, B. T., & Harr, T. (2017) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-017-8654-z · Cited by 356 · see citing works
The current understanding of Stevens–Johnson syndrome and toxic epidermal necrolysis
Mockenhaupt, M. (2011) · Expert Review of Clinical Immunology · doi:10.1586/eci.11.66 · Cited by 347 · see citing works
Kaplan, A. P., & Greaves, M. W. (2005) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2004.09.032 · Cited by 310 · see citing works
Definition of supertypes for HLA molecules using clustering of specificity matrices
Lund, O., Nielsen, M., Keşmir, C., Petersen, A. G., R�der, G., Justesen, S. F. L., Lundegaard, C., Worning, P., Sylvester‐Hvid, C., Lamberth, K., et al. (2004) · Immunogenetics · doi:10.1007/s00251-004-0647-4 · Cited by 292 · see citing works
Cho, Y., Yang, C., & Chu, C. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061243 · Cited by 286 · see citing works
Genetic Susceptibility to Toxic Epidermal Necrolysis
Roujeau, J. (1987) · Archives of Dermatology · doi:10.1001/archderm.1987.01660330082014 · Cited by 277 · see citing works
The Culprit Drugs in 87 Cases of Toxic Epidermal Necrolysis (Lyell's Syndrome)
Guillaume, J.-C. (1987) · Archives of Dermatology · doi:10.1001/archderm.1987.01660330077013 · Cited by 249 · see citing works
Clinical Role of Human Leukocyte Antigen in Health and Disease
Mosaad, Y. M. (2015) · Scandinavian Journal of Immunology · doi:10.1111/sji.12329 · Cited by 208 · see citing works
Gruchalla, R. S. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.93 · Cited by 162 · see citing works
Antimicrobial sulfonamide drugs
Tačić, A., Nikolić, V. D., Nikolic, L. B., & Savic, I. M. (2017) · Advanced technologies · doi:10.5937/savteh1701058t · Cited by 158 · see citing works
Sharifzadeh, S., Mohammadpour, A. H., Tavanaee, A., & Elyasi, S. (2020) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-020-03005-9 · Cited by 131 · see citing works
Carr, A. D., Swanson, C. E., Penny, R., & Cooper, D. A. (1993) · The Journal of Infectious Diseases · doi:10.1093/infdis/167.1.180 · Cited by 126 · see citing works
Pruritus: Progress toward Pathogenesis and Treatment
Song, J., Xian, D., Yang, L., Xiong, X., Lai, R., & Zhong, J. (2018) · BioMed Research International · doi:10.1155/2018/9625936 · Cited by 124 · see citing works
Angioedema: Manifestations and management
Greaves, M. W., & Lawlor, F. (1991) · Journal of the American Academy of Dermatology · doi:10.1016/0190-9622(91)70183-3 · Cited by 112 · see citing works
Pruritus in allergy and immunology
Yang, T.-L. B., & Kim, B. S. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2019.06.016 · Cited by 112 · see citing works
The HLA system: immunobiology, HLA typing, antibody screening and crossmatching techniques
Howell, W. M., Carter, V., & Clark, B. (2010) · Journal of Clinical Pathology · doi:10.1136/jcp.2009.072371 · Cited by 94 · see citing works
Emerging concepts in the diagnosis and treatment of patients with undifferentiated angioedema
Bernstein, J. A., & Moellman, J. J. (2012) · International Journal of Emergency Medicine · doi:10.1186/1865-1380-5-39 · Cited by 91 · see citing works
Allergies to sulfonamide antibiotics and sulfur-containing drugs
Dibbern, D. A., & Montanaro, A. J. (2008) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)60415-2 · Cited by 90 · see citing works
Özkaya, E., & Akar, U. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.117854 · Cited by 90 · see citing works
Critical view of anaphylaxis epidemiology: open questions and new perspectives
Academies, O. B. T. J. A., Tanno, L. K., Bierrenbach, A. L., Simons, F. E. R., Cardona, V., Thong, B. Y., Molinari, N., Calderón, M. A., Worm, M., Chang, Y., et al. (2018) · Allergy Asthma and Clinical Immunology · doi:10.1186/s13223-018-0234-0 · Cited by 89 · see citing works
Sulfonamide Hypersensitivity: Fact and Fiction
Khan, D. A., Knowles, S. R., & Shear, N. H. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.05.034 · Cited by 87 · see citing works
Giles, A. B., Foushee, J. A., Lantz, E., & Gumina, G. (2019) · Pharmacy · doi:10.3390/pharmacy7030132 · Cited by 85 · see citing works
Drug-induced uveitis: A review
Agarwal, M., Majumder, P. D., Babu, K., Konana, V., Goyal, M., Touhami, S., Stanescu, D., & Bodaghi, B. (2020) · Indian Journal of Ophthalmology · doi:10.4103/ijo.ijo_816_20 · Cited by 75 · see citing works
The management of toxic epidermal necrolysis
Fernando, S. L. (2012) · Australasian Journal of Dermatology · doi:10.1111/j.1440-0960.2011.00862.x · Cited by 73 · see citing works
Moorthy, R. S., London, N. J. S., Garg, S. J., & Cunningham, E. T. (2013) · Current Opinion in Ophthalmology · doi:10.1097/01.icu.0000434534.32063.5c · Cited by 73 · see citing works
Review of Toxic Epidermal Necrolysis
Harris, V., Jackson, C., & Cooper, A. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122135 · Cited by 73 · see citing works
Cross-Reactivity in Drug Hypersensitivity Reactions to Sulfasalazine and Sulfamethoxazole
Gschwend, A., Lochmatter, P., Beeler, A., & Pichler, W. J. (2010) · International Archives of Allergy and Immunology · doi:10.1159/000312632 · Cited by 67 · see citing works
Novel Treatments for Drug-Induced Toxic Epidermal Necrolysis (Lyell’s Syndrome)
Paquet, P., Pierard, G., & Quatresooz, P. (2005) · International Archives of Allergy and Immunology · doi:10.1159/000083947 · Cited by 52 · see citing works
Systemic Sulfonamides as a Cause of Bilateral, Anterior Uveitis
Tilden, M. E. (1991) · Archives of Ophthalmology · doi:10.1001/archopht.1991.01080010069035 · Cited by 50 · see citing works
Schnyder, B., & Pichler, W. J. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.10.003 · Cited by 50 · see citing works
Evaluation and management of angioedema of the head and neck
Baş, M., Hoffmann, T. K., & Kojda, G. (2006) · Current Opinion in Otolaryngology & Head & Neck Surgery · doi:10.1097/01.moo.0000193202.85837.7d · Cited by 45 · see citing works
Komatsu‐Fujii, T., Kaneko, S., Chinuki, Y., Suyama, Y., Ohta, M., Niihara, H., & Morita, E. (2016) · Allergology International · doi:10.1016/j.alit.2016.06.003 · Cited by 43 · see citing works
Diagnosis and treatment of pruritus.
Nowak, D. A., & Yeung, J. (2017) · PubMed · Cited by 42 · see citing works
Eosinophilic sialodochitis: redefinition of ‘allergic parotitis’ and ‘sialodochitis fibrinosa’
Baer, A., Okuhama, A., Eisele, D., Tversky, J., & Gniadek, T. (2016) · Oral Diseases · doi:10.1111/odi.12595 · Cited by 40 · see citing works
Pichler, W. J. (2008) · doi:10.1002/9781444300918.ch94 · Cited by 37 · see citing works
Acute Pancreatitis Induced by Methimazole in a Patient with Graves' Disease
Yang, M., Qu, H., & Deng, H. (2011) · Thyroid · doi:10.1089/thy.2011.0210 · Cited by 35 · see citing works
Cordero‐Coma, M., Méndez, R. S., Garzo-García, I., & Yilmaz, T. (2014) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2015.972363 · Cited by 35 · see citing works
Acute pancreatitis and parotitis induced by methimazole in a patient with Graves' disease
Taguchi, M., Yokota, M., Koyano, H. M., Endo, Y., & Ozawa, Y. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00888.x · Cited by 34 · see citing works
Genetic markers of severe cutaneous adverse reactions
Jung, J., Kim, J.-Y., Park, I., Choi, B. W., & Kang, H. (2018) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2018.126 · Cited by 34 · see citing works
Nakamura, R., Ozeki, T., Hirayama, N., Sekine, A., Yamashita, T., Mashimo, Y., Mizukawa, Y., Shiohara, T., Watanabe, H., Sueki, H., et al. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.12.025 · Cited by 34 · see citing works
Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides
Neuman, M. G., Shear, N. H., Malkiewicz, I. M., Taeri, M., Shapiro, L. E., Krivoy, N., Haber, J. A., Gómez, M., Fish, J. S., Cartotto, R. C., et al. (2007) · Translational research · doi:10.1016/j.trsl.2006.12.001 · Cited by 31 · see citing works
Role of Oxidative Stress in Hypersensitivity Reactions to Sulfonamides
Elzagallaai, A. A., Sultan, E. A., Bend, J. R., Abuzgaia, A. M., Loubani, E., & Rieder, M. J. (2019) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.1535 · Cited by 31 · see citing works
Pruritus: an updated look at an old problem.
Tivoli, Y. A., & Rubenstein, R. M. (2009) · PubMed · Cited by 31 · see citing works
Familial Occurrence of Stevens Johnson Syndrome
Fischer, P. R. (1983) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1983.02140350086023 · Cited by 24 · see citing works
Cutaneous Adverse Events Caused by Sulfonamide-Containing Drugs: Reality or Perception?
Shah, F., & Bell, I. M. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b01932 · Cited by 24 · see citing works
Ebata, T. (2016) · Current problems in dermatology · doi:10.1159/000446084 · Cited by 22 · see citing works
DRESS syndrome caused by nitrofurantoin.
Velema, M. S., & Voerman, H. J. (2009) · PubMed · Cited by 20 · see citing works
Drug hypersensitivity: We need to do more
Pichler, W. J., & Yerly, D. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.11.002 · Cited by 15 · see citing works
Ratajczak, H. V. (2004) · Toxicological Reviews · doi:10.2165/00139709-200423040-00006 · Cited by 14 · see citing works
Reinhart, J. M., Motsinger‐Reif, A. A., Dickey, A. N., Yale, S. H., & Trepanier, L. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156000 · Cited by 14 · see citing works
Tarbox, J. A., Bansal, A., & Peiris, A. N. (2018) · JAMA · doi:10.1001/jama.2018.4860 · Cited by 12 · see citing works
Davis, W. D., & Schafer, P. A. (2018) · Advanced Emergency Nursing Journal · doi:10.1097/tme.0000000000000197 · Cited by 10 · see citing works
Sasi, S., Altarawneh, H. N., Petkar, M. A., & Nair, A. P. (2020) · Case Reports in Acute Medicine · doi:10.1159/000509712 · Cited by 10 · see citing works
Seventeen-year-old sexually active male with rash
Boyd, A. H., Mills, D. A., Hook, K. P., & Kaila, R. (2015) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2015.08.043 · Cited by 7 · see citing works
Wu, S., Shi, H., Cao, N., Ye, L., Yu, C., & Zheng, L. (2018) · Acta Oto-Laryngologica · doi:10.1080/00016489.2018.1515498 · Cited by 7 · see citing works
Acute Parotitis Induced by Trimethoprim/Sulfamethoxazole
Patel, J. S., & Scheiner, E. D. (2011) · Ear Nose & Throat Journal · doi:10.1177/014556131109000214 · Cited by 6 · see citing works
Stevens-Johnson syndrome and toxic epidermal necrolysis
Wildermuth, A. (2020) · JAAPA · doi:10.1097/01.jaa.0000684164.28009.4a · Cited by 6 · see citing works
Presumed Sulfonamide-Associated Uveitis With Stevens-Johnson Syndrome in a Quarter Horse Mare
Potocnik, E., Drozdzewska, K., & Schwarz, B. (2019) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2019.02.004 · Cited by 4 · see citing works
An unusual case of acute parotitis in a young adult
Sehic, A., Haenig, C., & Spear, F. (2017) · JAAPA · doi:10.1097/01.jaa.0000521134.30915.a9 · Cited by 3 · see citing works
New Advances in Drug Hypersensitivity Research and Treatment
Tsai, Y., Chung, W., Abe, R., & Tassaneeyakul, W. (2018) · Journal of Immunology Research · doi:10.1155/2018/9345078 · Cited by 2 · see citing works
Management of Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Daniel, B. S., Joly, P., & Murrell, D. F. (2015) · Springer eBooks · doi:10.1007/978-3-662-45698-9_66 · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- [28]Mindel J, Uveitis D. Therapeutic Review. Clin Ther. 1998; 42: 6.
- [32]Pichler WJ. Drug Hypersensitivity. 5th ed. Elsevier Ltd; 2009. Vol. 2. doi: 10.1002/9781444300918.ch94 · DOI
- [62]Misery L, Stander S. Pruritus. London: Springer; 2010.
Cited by
Sorted by citations
A Comprehensive Review of Sulfonamide Hypersensitivity: Implications for Clinical Practice
Arias, B. S., Zúñiga, A. A., Garbanzo, J. D. W., Rojas‐Barrantes, Z., Arguedas‐Chacón, S., & Zavaleta‐Monestel, E. (2024) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-023-08978-w · Cited by 27 · see citing works
Charoenkwan, P., Schaduangrat, N., Phan, L. T., Manavalan, B., & Shoombuatong, W. (2024) · Future Generation Computer Systems · doi:10.1016/j.future.2024.07.033 · Cited by 22 · see citing works
Jian, N., Dai, Y., Liu, H., Wu, N., Liu, L., Wu, D., & Wu, Y. (2023) · Analytica Chimica Acta · doi:10.1016/j.aca.2023.342163 · Cited by 20 · see citing works
The status and natural impact of floriculture production in Ethiopia: a systematic review
Gelaye, Y. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-24279-9 · Cited by 16 · see citing works
Fei, W., Shen, J., & Cai, H. (2023) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s422928 · Cited by 13 · see citing works
Wung, C.-H., Wang, C., Lai, K., Chen, C., Chen, W., Chung, W., & Chung, W. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1183491 · Cited by 10 · see citing works
Case report: Alpelisib-induced Stevens–Johnson syndrome
Kurian, C. J., Desai, A. N., Rafferty, W., & Hussein, A. K. A. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.954027 · Cited by 7 · see citing works
Genetic Variations and Antibiotic-Related Adverse Events
Principi, N., Petropulacos, K., & Esposito, S. (2024) · Pharmaceuticals · doi:10.3390/ph17030331 · Cited by 6 · see citing works
Liu, P., Yu, Y., Mo, H., Lin, J., Luo, L., & Wei, X. (2025) · Talanta · doi:10.1016/j.talanta.2025.128628 · Cited by 5 · see citing works
Jain, R., Aishwarya, D., Wankhade, S., Anupriya, Kumarasamy, M., & Peraman, R. (2024) · Biomedical Chromatography · doi:10.1002/bmc.6025 · Cited by 4 · see citing works
Zarafu, I., Mușat, I., Limban, C., Nuță, D. C., Dulamă, I. D., Rădulescu, C., Ştirbescu, R. M., Tatibouët, A., Chifiriuc, M. C., Marutescu, L. G., et al. (2025) · Molecules · doi:10.3390/molecules30122585 · Cited by 4 · see citing works
The Silent Culprit: Drug-Induced Fever Associated With Trimethoprim-Sulfamethoxazole
Lages, M., Coelho, C., Cadinha, S., & Lopes, J. B. (2025) · Cureus · doi:10.7759/cureus.96994 · Cited by 3 · see citing works
COVID-19 and severe cutaneous allergic reactions to sulfonamides
Deng, E., Craig, T., Nguyen, D. V., & Al‐Shaikhly, T. (2024) · Allergy and Asthma Proceedings · doi:10.2500/aap.2024.45.240086 · Cited by 3 · see citing works
Smatti, M. K., Jan, Z., & Yassine, H. M. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100136 · Cited by 2 · see citing works
Devliya, B., Al-Kubeisi, A. K., Patel, D., Dabhi, M., Patel, B., Thakar, M. S., Nagapara, J., Chauhan, S. J., Rajput, K., Goswami, D., et al. (2026) · RSC Advances · doi:10.1039/d6ra01925k · Cited by 2 · see citing works
Rotimi, K., Fagbemi, B., Ibinaiye, T., Aiden, J., Gabriel, V., Dabes, C., Kyeshir, T., Oguche, D., Obayemi, O., Biambo, A. A., et al. (2023) · Bulletin of the National Research Centre/Bulletin of the National Research Center · doi:10.1186/s42269-023-01035-8 · Cited by 2 · see citing works
Abdelfatah, R. M., Farid, N. F., Badr-Eldien, M. M., & Tohamy, S. I. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.114968 · Cited by 2 · see citing works
Lanphier, R. M., Latham, B. D., Gerringer, A. J., Interrante, T., Jones, C. D., De Buysscher, T., Fallon, J. K., & Jackson, K. D. (2025) · Drug Metabolism and Disposition · doi:10.1016/j.dmd.2025.100195 · Cited by 1 · see citing works
Li, X., Zhou, W., Zhao, K., & Li, Y. (2024) · Medicine · doi:10.1097/md.0000000000039535 · Cited by 1 · see citing works
Stasiuk, M., Brzeski, J., Maciejewska, N., Brzeska, S., Ciura, K., Kazimierczuk, K., Zarzeczańska, D., Greber, K. E., Dębowski, D., & Makowski, M. (2026) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2026.145415 · Cited by 1 · see citing works
Horn, S. R., Ghaffari, G., & Al‐Shaikhly, T. (2026) · Allergy and Asthma Proceedings · doi:10.2500/aap.2026.47.260019 · Cited by 1 · see citing works
Raya, I., Romero‐Parra, R. M., Yasin, G., Jalil, A. T., & Muzammil, K. (2023) · Polycyclic aromatic compounds · doi:10.1080/10406638.2023.2186447
Cutaneous Adverse Drug Events in Older Adults
Ahmed, S., & Dharmarajan, T. S. (2025) · Springer eBooks · doi:10.1007/978-3-031-53888-9_8-1
Sultana, S., Shuvo, M. H., Zaman, F., Tasnub, M. S. A., Kabir, E., & Uzzaman, M. (2026) · In Silico Pharmacology · doi:10.1007/s40203-025-00526-y
Bocheva, G., Szepietowski, J. C., & Reich, A. (2026) · Acta Medica Bulgarica · doi:10.2478/amb-2026-0047
Hu, Y., Wang, J., Wang, Z., Zhang, Y., He, X., Zhao, M., Lu, S., Zhang, B., & Yang, Y. S. (2026) · Frontiers in Pediatrics · doi:10.3389/fped.2026.1844553
Shaaban, H., Alqarni, A. M., Mostafa, A., Aldossary, T., Bunajmah, N., Almusaher, H., Albugami, S. A., AlSumain, G., & AlAnsari, F. (2026) · Antibiotics · doi:10.3390/antibiotics15100981
- Authors
- Asyraf, P. A., Kusnadi, I. F., Stefanus, J., Khairinisa, M. A., & Abdulah, R.
- Affiliations
- Padjadjaran University (ID)
- Corresponding author
- Khairinisa, Miski Aghnia
- Venue
- Drug Healthcare and Patient Safety
- Publisher
- Informa UK Limited
- Published
- 2022-07
- Volume
- Volume 14
- Pages
- 113-124
- ISSN
- 1179-1365 (ISSN-L)
- PMC
- PMC9315057
- OpenAlex
- W4286255610
- Cited by
- 27
- References
- 72
- Citations by year
- 2026: 8 · 2025: 6 · 2024: 6 · 2023: 5 · 2022: 2
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Drug Healthcare and Patient Safety (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Funders
- Universitas Padjadjaran
- Topics
- Health Sciences › Medicine › Pharmacology › Drug-Induced Adverse Reactions
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Keywords
- sulfonamide hypersensitivity, drug hypersensitivity, adverse drug reactions, HLA alleles, HLA-A29, HLA-B12, HLA-DR7, HLA-B44, HLA-A*11:01, Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome, uveitis, angioedema, parotitis, pruritus, rash
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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