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Functionalized carbon nanotubes: biomedical applications
Open accessAbstract
Carbon nanotubes (CNTs) are emerging as novel nanomaterials for various biomedical applications. CNTs can be used to deliver a variety of therapeutic agents, including biomolecules, to the target disease sites. In addition, their unparalleled optical and electrical properties make them excellent candidates for bioimaging and other biomedical applications. However, the high cytotoxicity of CNTs limits their use in humans and many biological systems. The biocompatibility and low cytotoxicity of CNTs are attributed to size, dose, duration, testing systems, and surface functionalization. The functionalization of CNTs improves their solubility and biocompatibility and alters their cellular interaction pathways, resulting in much-reduced cytotoxic effects. Functionalized CNTs are promising novel materials for a variety of biomedical applications. These potential applications are particularly enhanced by their ability to penetrate biological membranes with relatively low cytotoxicity. This review is directed towards the overview of CNTs and their functionalization for biomedical applications with minimal cytotoxicity.
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Cites
Amphiphilic block copolymers for drug delivery
Adams, M. L., Lavasanifar, A., & Kwon, G. S. (2003) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10397 · Cited by 1,078
Pacurari, M., Yin, X. J., Zhao, J., Ding, M., Leonard, S. S., Schwegler-Berry, D., Ducatman, B. S., Sbarra, D., Hoover, M. D., Castranova, V., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10924 · Cited by 372
Cited by
Mazari, S. A., Ali, E., Abro, R., Khan, F. S. A., Ahmed, I., Ahmed, M., Nizamuddin, S., Siddiqui, T. H., Hossain, N., Mubarak, N. M., et al. (2021) · Journal of Environmental Chemical Engineering · doi:10.1016/j.jece.2021.105028 · Cited by 316
Xue, X., Wang, L.-R., Sato, Y., Jiang, Y., Berg, M., Yang, D.-S., Nixon, R. A., & Liang, X.-J. (2014) · Nano Letters · doi:10.1021/nl501839q · Cited by 125
Castro, M. O., de Santiago, M. Q., Nascimento, K. S., Sousa Cavada, B., de Castro Miguel, E., de Paula, A. J., & Ferreira, O. P. (2017) · Journal of Materials Science · doi:10.1007/s10853-017-1441-7 · Cited by 14
Metadata
- Authors
- Singh, S., Vardharajula, S., Tiwari, P., Eroğlu, E., Vig, K., Dennis, V., & Ali
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2012-10
- Volume
- 7
- Pages
- 5361
- ISSN
- 1176-9114 (ISSN-L)
- 1178-2013
- OpenAlex
- W2048095806
- Cited by
- 485
- References
- 2
- FWCI
- 17.96
- Type
- journal article
- Language
- en
- Open access
- gold
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- Singh, S., Vardharajula, S., Tiwari, P., Eroğlu, E., Vig, K., Dennis, V., & Ali. (2012). Functionalized carbon nanotubes: biomedical applications. International Journal of Nanomedicine. https://doi.org/10.2147/ijn.s35832
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
