Cited by 19Fibromyalgia and Chronic Fatigue Syndrome ResearchGastrointestinal motility and disordersMotor Control and Adaptation

Gross and fine motor function in fibromyalgia and chronic fatigue syndrome

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Rasouli, Omid, Fors, Egil, Borchgrevink, Petter, Öhberg, Fredrik, Stensdotter, Ann-Katrin·2017·Journal of Pain Research

Abstract

Purpose: This paper aimed to investigate motor proficiency in fine and gross motor function, with a focus on reaction time (RT) and movement skill, in patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS) compared to healthy controls (HC). Methods: A total of 60 individuals (20 CFS, 20 FM, and 20 HC), age 19–49 years, participated in this study. Gross motor function in the lower extremity was assessed using a RT task during gait initiation in response to an auditory trigger. Fine motor function in the upper extremity was measured during a precision task (the Purdue Pegboard test) where the number of pins inserted within 30 s was counted. Results: No significant differences were found between FM and CFS in any parameters. FM and CFS groups had significantly longer RT than HC in the gait initiation ( p =0.001, and p =0.004 respectively). In the Purdue Pegboard test, 20% in the FM group, 15% in the CFS groups, and 0% of HC group, scored below the threshold of the accepted performance. However, there were no significant differences between FM, CFS, and HC in this task ( p =0.12). Conclusion: Compared to controls, both CFS and FM groups displayed significantly longer RT in the gait initiation task. Generally, FM patients showed the worst results in both tests, although no group differences were found in fine motor control, according to the Purdue Pegboard test. Keywords: fatigue syndrome, chronic, musculoskeletal diseases, gait initiation, Purdue ­Pegboard, reaction time

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  • FM was associated with an increased BMI, which was positively correlated with decreased reaction time during gait initiation.

    “FM was associated with an increased BMI, which was positively correlated with decreased reaction time during gait initiation.2”

    From A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment (2025) · cites this paper as [2]

    The Discussion says the FM group had the highest BMI, but the between-group BMI difference was not significant. It reports a positive correlation between weight—not BMI—and reaction time during gait initiation; the Results report longer, not decreased, reaction times for FM compared with healthy controls. (LLM, conf=0.88)

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  • Fibromyalgia is a disabling chronic pain syndrome characterized by multiple symptoms, including medically unexplained widespread pain, fatigue, cognitive, mood and sleep disorders.

    “Fibromyalgia (FM) is a disabling chronic pain syndrome characterized by multiple symptoms, including medically unexplained widespread pain, fatigue, cognitive, mood and sleep disorders.1–11”

    From A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment (2025) · cites this paper as [2]

    The Introduction describes fibromyalgia as characterized by chronic widespread pain, reports cognitive complaints, and notes substantial symptom overlap with chronic fatigue syndrome. The Discussion says newer diagnostic criteria include fatigue and cognition. The passages do not describe mood or sleep disorders as features of fibromyalgia, or characterize its pain as medically unexplained. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • High BMI and inactivity may exacerbate motor deficits and perpetuate the cycle of disability.

    “High BMI and inactivity may exacerbate motor deficits and perpetuate the cycle of disability.2,17”

    From A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment (2025) · cites this paper as [2]

    The Discussion (page not provided) says high BMI may impair fine and gross motor skills and that low physical activity may adversely affect motor proficiency in patients with fibromyalgia or chronic fatigue syndrome. It also links avoidance of pain and fatigue to inactivity and deconditioning, but does not establish that these factors perpetuate a cycle of disability. (LLM, conf=0.84)

    Experimental — accuracy not yet measured
  • Patients with FM present with slower gait speed, reduced stride length, delayed gait initiation, altered postural sway, and altered muscle activation patterns during walking.

    “Patients with FM present with slower gait speed, reduced stride length, delayed gait initiation, altered postural sway,2,21 and altered muscle activation patterns during walking.30”

    From A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment (2025) · cites this paper as [2]

    The Results (Gait initiation; page not provided) report significantly longer gait-initiation reaction times in patients with FM than in healthy controls. The Introduction also reports reduced gait velocity in FM. Our copy does not establish reduced stride length or altered postural sway; the separately cited muscle-activation clause is not necessary to this verdict. (LLM, conf=0.84)

    Experimental — accuracy not yet measured
  • Low levels of physical activity were correlated with poor motor control, lower movement velocity, and a higher body mass index (BMI), which are typical in FM populations.

    “Low levels of physical activity were correlated with poor motor control, lower movement velocity, and a higher body mass index (BMI), which are typical in FM populations.”

    From A Review of Movement and Functional Impairments in Fibromyalgia: Implications for Targeted Treatment (2025) · cites this paper as [2]

    The Discussion says low physical activity is common in FM and may be correlated with poor motor control and lower movement velocity. It also says high BMI is common in FM, but does not establish a correlation between BMI and physical activity. The claim presents the tentative motor-control association as an established correlation. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

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Authors
Rasouli, O., Fors, E., Borchgrevink, P., Öhberg, F., & Stensdotter, A.-K.
Affiliations
  • Norwegian University of Science and Technology (NO)
  • Umeå University (SE)
Corresponding author
Rasouli, Omid
Venue
Journal of Pain Research
Published
2017-02
Volume
Volume 10
Pages
303-309
ISSN
1178-7090 (ISSN-L)
OpenAlex
W2587100346
Cited by
19
References
4
Citations by year
2025: 1 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 4 · 2017: 1
FWCI
2.02
Type
journal article
Language
en
Open access
Locations
  • Journal of Pain Research (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • BIBSYS Brage (BIBSYS (Norway)) (acceptedVersion, cc-by-nc)
  • DiVA at Umeå University (Umeå University) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
  • NORA - Norwegian Open Research Archives (submittedVersion, cc-by-nc)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
Keywords
fibromyalgia, chronic fatigue syndrome, gross motor function, fine motor function, reaction time, gait initiation, Purdue Pegboard Test, motor competence, lower extremity, upper limb

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