The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Chitosan nanoparticles for oral drug and gene delivery
Open accessAbstract
Chitosan is a widely available, mucoadhesive polymer that is able to increase cellular permeability and improve the bioavailability of orally administered protein drugs. It can also be readily formed into nanoparticles able to entrap drugs or condense plasmid DNA. Studies on the formulation and oral delivery of such chitosan nanoparticles have demonstrated their efficacy in enhancing drug uptake and promoting gene expression. This review summarizes some of these findings and highlights the potential of chitosan as a component of oral delivery systems.
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Cites
The Mechanism of Uptake of Biodegradable Microparticles in Caco-2 Cells Is Size Dependent
Desai, M. P., Labhasetwar, V., Walter, E., Levy, R. J., & Amidon, G. L. (1997) · Pharmaceutical Research · doi:10.1023/a:1012126301290 · Cited by 858
Neutra, M., Phillips, T., Mayer, E., & Fishkind, D. (1987) · Cell and Tissue Research · doi:10.1007/bf00215747 · Cited by 253
Cited by
Insights into the mode of action of chitosan as an antibacterial compound.
Raafat, D., von Bargen, K., Haas, A., & Sahl, H.-G. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00453-08 · Cited by 888
Role of nanoparticle size, shape and surface chemistry in oral drug delivery
Banerjee, A., Qi, J., Gogoi, R., Wong, J., & Mitragotri, S. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.07.051 · Cited by 773
Harugade, A., Sherje, A. P., & Pethe, A. (2023) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2023.105634 · Cited by 474
Jin, Y., Song, Y., Zhu, X., Zhou, D., Chen, C., Zhang, Z., & Huang, Y. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.075 · Cited by 301
Liu, Z., Lv, D., Liu, S., Gong, J., Wang, D., Xiong, M., Chen, X., Xiang, R., & Tan, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060190 · Cited by 108
Metadata
- Authors
- Bowman, K., & Leong, K. W.
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2006-01
- Volume
- 1
- Issue
- 2
- Pages
- 117-128
- ISSN
- 1176-9114 (ISSN-L)
- OpenAlex
- W2051894319
- Cited by
- 439
- References
- 2
- FWCI
- 5.32
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bowman, K., & Leong, K. W. (2006). Chitosan nanoparticles for oral drug and gene delivery. International Journal of Nanomedicine. https://doi.org/10.2147/nano.2006.1.2.117
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
