The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Functionalized gold nanoparticles for the binding, stabilization, and delivery of therapeutic DNA, RNA, and other biological macromolecules
Open accessAbstract
Nanotechnology has virtually exploded in the last few years with seemingly limitless opportunity across all segments of our society. If gene and RNA therapy are to ever realize their full potential, there is a great need for nanomaterials that can bind, stabilize, and deliver these macromolecular nucleic acids into human cells and tissues. Many researchers have turned to gold nanomaterials, as gold is thought to be relatively well tolerated in humans and provides an inert material upon which nucleic acids can attach. Here, we review the various strategies for associating macromolecular nucleic acids to the surface of gold nanoparticles (GNPs), the characterization chemistries involved, and the potential advantages of GNPs in terms of stabilization and delivery.
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Citations
Cites
Remote Optical Switch for Localized and Selective Control of Gene Interference
Lee, S. E., Liu, G. L., Kim, F., & Lee, L. P. (2009) · Nano Letters · doi:10.1021/nl802689k · Cited by 224
Cited by
Various methods of gold nanoparticles (GNPs) conjugation to antibodies
Jazayeri, M. H., Amani, H., Pourfatollah, A. A., Pazoki-Toroudi, H., & Sedighimoghaddam, B. (2016) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2016.04.002 · Cited by 528
Gold nanoparticles in cancer therapy
Lim, Z.-Z. J., Li, J.-E. J., Ng, C.-T., Yung, L.-Y. L., & Bay, B.-H. (2011) · Acta Pharmacologica Sinica · doi:10.1038/aps.2011.82 · Cited by 314
Metadata
- Authors
- DeLong, R., Wanekaya, D. A., Reynolds, M. C., & Schaeffer, A.
- Venue
- Nanotechnology, Science and Applications
- Publisher
- Informa UK Limited
- Published
- 2010-09
- Volume
- 3
- Pages
- 53
- ISSN
- 1177-8903 (ISSN-L)
- OpenAlex
- W2114369956
- Cited by
- 217
- References
- 1
- FWCI
- 2.24
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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