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Whole slide imaging in pathology: advantages, limitations, and emerging perspectives

Open access
Pantanowitz, Liron, Farahani, Navid, Parwani, Anil·2015·Pathology and Laboratory Medicine International

Abstract

Abstract: Significant technologic gains have led to the adoption of innovative digital imaging solutions in pathology. Whole slide imaging (WSI), which refers to scanning of conventional glass slides in order to produce digital slides, is the most recent imaging modality being employed by pathology departments worldwide. WSI continues to gain traction among pathologists for diagnostic, educational, and research purposes. This article provides a technologic review of WSI platforms and covers clinical and nonclinical pathology applications of these imaging systems. Barriers to adoption of WSI include limiting technology, image quality, problems with scanning all materials (eg, cytology slides), cost, digital slide storage, inability to handle high-throughput routine work, regulatory barriers, ergonomics, and pathologists' reluctance. Emerging issues related to clinical validation, standardization, and forthcoming advances in the field are also addressed. Keywords: digital, imaging, microscopy, pathology, validation, whole slide image, telepathology

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Metadata

Authors
Pantanowitz, L., Farahani, N., & Parwani, A.
Venue
Pathology and Laboratory Medicine International
Published
2015-06
Pages
23
ISSN
1179-2698 (ISSN-L)
OpenAlex
W1656766859
Cited by
373
References
0
FWCI
22.84
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Whole slide imaging in pathology: advantages, limitations, and emerging perspectives. https://app.cochat.ai/papers/10.2147/plmi.s59826
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Pantanowitz, L., Farahani, N., & Parwani, A. (2015). Whole slide imaging in pathology: advantages, limitations, and emerging perspectives. Pathology and Laboratory Medicine International. https://doi.org/10.2147/plmi.s59826

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.