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Preliminary Studies of the Cytotoxicity and Photoprotective Properties of Benzophenone and Lactone Derivatives
Open accessAbstract
Ultraviolet solar radiation can generate free radicals that damage skin and cause skin lesions or skin cancer.Sunscreens are a protective measure against the effects of solar radiation that protects the skin by absorbing or reflecting solar rays.Ideally, the sunscreen should protect the skin against UVB (290-320 nm) and UVA (320-400 nm) rays, be photostable and non-toxic.This work describes a preliminary study on the SPF of a benzophenone and a lactone derivative.The synthesized compounds were characterized by spectroscopic techniques, submitted to cell viability assays against MTT and SPF determined in vitro by UV/VIS spectroscopy measurements.The spectroscopic data was in agreement with the proposed structures of the compounds studied.The SPF was proportional to concentration, and in one case, the sun protection factor was lower at higher concentrations.The benzophenone derivatives were evaluated for toxicity by a cell viability study, and found to be non-cytotoxic at the tested concentrations.
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Benzophenone 69 and lactone 70 displayed UV filter properties; lactone 70 had a more potent photoprotective effect (SPF = 16) but only absorbed UVB radiation, whereas benzophenone 69 absorbed UVA radiation.
“In addition to these benzophenones, the structure-related benzophenone 69 and lactone 70 displayed UV filter properties, having lactone 70, a more potent photoprotective effect (SPF = 16), but only ability to absorb UVB radiation, contrarily to benzophenone 69, which demonstrated the ability to absorb UVA radiation [132].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [132]
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References 12 · Cited by 4
Research works printed but not linked: 15
- Photochemistry and Photobiology B: Biology 2006, 82, 204. [CrossRef] [PubMed] · DOI
- Reena, R.; Sirinivas, C. R. Photoprotetion. Indian Journal Dermatology Venerology and Leprology 2007, 73, 73. [CrossRef · DOI
- Shaatan, N. A. The chemistry of sunscreens. Cosmetics & Toiletries 1998, 101, 55.
- CrossRef · DOI
- Nascimento, L. F.; Santos, E. P.; Aguiar, A. P.; Fotoprotetores Orgânicos: Pesquisa, Inovação e a Importância da Síntese Orgânica. Revista Virtual de Química 2014, 6, 190. [CrossRef · DOI
- Shaath, N. A.; Sunscreens Development, Evaluation, and Regulatory Aspects. Wiley: New York; 1997.
- Ramos, M. F. S.; Bizarri, C. H. B.; Mattos, H. A.; Padilha, M. R. S.; Duarte, H. M.; Preliminary studies towards utilization of various plant extracts as antisolar agents. International Journal of Cosmetics Science 1996, 18, 87. [CrossRef · DOI
- Violante, I. M. P.; De Souza, I. M.; Venturini, C. L.; Ramalho, A. F. S.; Santos, R. A. N.; Ferrari, M. Estudo preliminar da atividade fotoprotetora in vitro de extratos vegetais do cerrado de Mato Grosso. Revista Brasileira de Farmácia 2008, 89, 175. [Link]
- Leite, F. C. A.; Reis, S. A. G. B.; Rolim, L. A.; Araújo C. R. M.; Gonçalves, A. A. Síntese de derivados da Vanilina e Avaliação como Agentes Fotoprotetores frente à Radiação UVB. Revista Virtual de Química 2016, 8, 2057. [CrossRef] · DOI
- Nascimento, C. S.; Nunes, L. C. C.; De Lima, Á. A. N.; Grangeiro, J. S.; Rolim, N. P. J. Incremento do FPS em formulação de protetor solar utilizando extratos de própolis verde e vermelha. Revista Brasileira de Farmácia 2009, 30, 334. [Link]
- Jain, A.; Rani, V. Assessment of herb-drug synergy to combat doxorubicin induced cardiotoxicity. Life Sciences 2018, 9, 30278. [CrossRef] · DOI
- Cheng, C. Y.; Liu, C. J.; Huang, Y. C.; Wu, S. H.; Fang, H. W.; Chen, Y. J. BI2536 induces mitotic catastrophe and radio sensitization in human oral cancer cells. Oncotarget 2018, 20, 21231. [CrossRef] [PubMed] · DOI
- VakiliZahir, N.; Nakhjavani, M.; Hajian, P.; Shirazi, F. H.; Mirzaei, H. Evaluation of Silibinin Effects on the Viability of HepG2 (Human hepatocellular liver carcinoma) and HUVEC (Human Umbilical Vein Endothelial) Cell Lines. Iranian Journal of Pharmaceutical Research 2018, 17, 261.
- Aksakal, B.; Demirel, M.; Sinirlioglu, Z. A. Synthesizing selenium-and silver-substituted hydroxyapatite -based bone grafts and their effects on antibacterial efficiency and cell viability. Biomed Tech (Berl) 2018, 8, 262. [CrossRef] [PubMed] · DOI
- Planck, M.; The Theory of Heat Radiation, Dover. Wiley: New York, 1959.
Metadata
- Authors
- da C. Gonçalves, M., G. Taylor, J., Rossoni Junior, J. V., S. Rabelo, A. C., C. Costa, D., Cazati, T., & M. R. dos Santos, V.
- Affiliations
- Universidade Federal de Ouro Preto (BR)
- ORCID
- Cazati, Thiago
- Venue
- Revista Virtual de Química
- Published
- 2018
- Volume
- 10
- Issue
- 3
- Pages
- 600-608
- ISSN
- 1984-6835 (ISSN-L)
- OpenAlex
- W2810727236
- Cited by
- 4
- References
- 12
- Citations by year
- 2024: 1 · 2022: 2 · 2019: 1
- FWCI
- 0.27
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Revista Virtual de Química (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Physical Sciences › Materials Science › Materials Chemistry › Photochromic and Fluorescence Chemistry
- Physical Sciences › Chemistry › Organic Chemistry › Heterocyclic Compound Synthesis and Bioactivity
- Keywords
- benzophenone derivatives, lactone derivatives, sunscreen, sun protection factor, UV-B radiation, UVA, photoprotection, cytotoxicity, cell viability, photostability, free radicals, skin cancer prevention
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