CoChat
Sign Up
Cited by 142Adipokines, Inflammation, and Metabolic DiseasesAtherosclerosis and Cardiovascular DiseasesCardiovascular Disease and Adiposity

The DOI matches its Crossref record; 133 of the 133 references it cites were found in a registry or an index.

Inflammation, Adiponectin, Obesity and Cardiovascular Risk

Mangge, H., Almer, G., Truschnig-Wilders, M., Schmidt, A., Gasser, R., Fuchs, D.·2010·Current Medicinal Chemistry
DOI 10.2174/092986710794183006
Open this paper in CoChat — free account

Abstract

The development of atherosclerotic lesions leading to myocardial infarction (MI) or stroke encompasses a cascade of cellular and molecular events that can well be characterized as a chronic immune-mediated inflammation occurring preferentially in the biologic surrounding of the so called metabolic syndrome. Adipokines, chemokines, cytokines, and their receptors are critically involved in the initiation and perpetuation of atherosclerosis, and they play important roles at all levels in the pathogenesis of this disease. Metabolic risk profiles associated with sedentary lifestyle, obesity, especially intra-abdominal fat accumulation, insulin resistance, and dyslipidemia pave the way for a chronic, immunemediated vascular inflammation around vascular lipid deposits. In the present article, the impact of adiponectin, monocyte and T-cell associated cytokines (with emphasis on Neopterin), individual adipose tissue - distribution, and pleiotropic drug effects on the individual course of atherosclerosis and associated cardiovascular disease are reviewed. Keywords: Adiposity, immune-mediated inflammation, cardiovascular risk, atherosclerotic lesions, metabolic syndrome, adiponectin, monocyte, T-cell, cytokines, Neopterin, cardiovascular disease (CVD), systemic disease, T-lymphocytes, neopterin,obesity, myocardial infarction (MI), homocystein, lowdensity lipoproteins (LDL), atherogenesis, angiogenesis, high sensitive C-reactive protein (hsCRP), intima-media thickness, remodelling, cytokine, chemokine, metalloproteinase, dendritic, foam,osteoclast, nuclear factor, kappaB ligand, osteoprotegerin, T-helper lymphocytes of type 1 (Th-1), reactive oxygen species (ROS), macrophages, monocyte chemotactic protein (MCP), endocannabinoids, oxidation, anti-atherogenic role, sympathetic nervous system, Hypoxia, kappa-B, hypoadiponectinemia, nitric oxide (NO), endothelial NO synthase (eNOS), asymmetric dimethylarginine, bioavailibility, VSMCs, rheumatoid arthritis (RA), systemic lupus erythematodes

Overview

Integrity signals

Registry

Crossref · 10.2174/092986710794183006

Cites

133 of 133 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 133 references

Cited by

Sorted by citations

See all 142

Related

Metadata

Authors
Mangge, H., Almer, G., Truschnig-Wilders, M., Schmidt, A., Gasser, R., & Fuchs, D.
Affiliations
Medical University of Graz (AT)
Corresponding author
Fuchs, D.
ORCID
Venue
Current Medicinal Chemistry
Publisher
Bentham Science Publishers Ltd.
Published
2010-12-01
Volume
17
Issue
36
Pages
4511-4520
ISSN
0929-8673 (ISSN-L)
DOI
10.2174/092986710794183006
OpenAlex
W2134473992
Cited by
142
References
133
Citations by year
2026: 2 · 2024: 2 · 2023: 11 · 2022: 6 · 2021: 5 · 2020: 7 · 2019: 8 · 2018: 2 · 2017: 9 · 2016: 8 · 2015: 10 · 2014: 14 · 2013: 17 · 2012: 30
FWCI
13.50
Type
journal article
Language
en
Open access
closed
Locations
  • Current Medicinal Chemistry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
  • Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords
adiponectin, obesity, atherosclerosis, cardiovascular risk, metabolic syndrome, immune-mediated inflammation, neopterin, cytokines, chemokines, body fat distribution, insulin resistance, dyslipidemia, intra-abdominal fat, homocysteine, low-density lipoprotein, atherogenesis, angiogenesis, C-reactive protein, intima-media thickness, NF-κB, osteoprotegerin, reactive oxygen species, macrophages, MCP-1, endocannabinoids, hypoadiponectinemia, nitric oxide, asymmetric dimethylarginine, endothelial dysfunction, rheumatoid arthritis, systemic lupus erythematosus
MeSH terms
Animals, Cardiovascular Diseases, Humans, Inflammation, Obesity, Risk Factors, Adiponectin

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review