Cited by 39Malaria Research and ControlNanoparticle-Based Drug DeliveryPharmacology and Nanomedicine Research

The DOI matches its Crossref record; 313 of the 313 references it cites were found in a registry or an index.

Nanomedicine Against Malaria

Urban, Patricia, Fernandez-Busquets, Xavier·2014·Current Medicinal Chemistry

DOI 10.2174/09298673113206660292

Open this paper in CoChat — free account

Abstract

Malaria is arguably one of the main medical concerns worldwide because of the numbers of people affected, the severity of the disease and the complexity of the life cycle of its causative agent, the protist Plasmodium sp. The clinical, social and economic burden of malaria has led for the last 100 years to several waves of serious efforts to reach its control and eventual eradication, without success to this day. With the advent of nanoscience, renewed hopes have appeared of finally obtaining the long sought-after magic bullet against malaria in the form of a nanovector for the targeted delivery of antimalarial drugs exclusively to Plasmodium-infected cells. Different types of encapsulating structure, targeting molecule, and antimalarial compound will be discussed for the assembly of Trojan horse nanocapsules capable of targeting with complete specificity diseased cells and of delivering inside them their antimalarial cargo with the objective of eliminating the parasite with a single dose. Nanotechnology can also be applied to the discovery of new antimalarials through single-molecule manipulation approaches for the identification of novel drugs targeting essential molecular components of the parasite. Finally, methods for the diagnosis of malaria can benefit from nanotools applied to the design of microfluidic-based devices for the accurate identification of the parasite's strain, its precise infective load, and the relative content of the different stages of its life cycle, whose knowledge is essential for the administration of adequate therapies. The benefits and drawbacks of these nanosystems will be considered in different possible scenarios, including cost-related issues that might be hampering the development of nanotechnology-based medicines against malaria with the dubious argument that they are too expensive to be used in developing areas.

Integrity signals

Registry

Crossref · 10.2174/09298673113206660292

Cites

313 of 313 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

1 retracted

Items 201–313 of 313

Drug resistant falciparum malaria: clinical consequences and strategies for prevention
Price, R. N., & Nosten, F. H. (2001) · Drug Resistance Updates · doi:10.1054/drup.2001.0195 · Cited by 64
Adverse reactions to sulfa drugs: implications for malaria chemotherapy.
Björkman, A., & Phillips‐Howard, P. A. (1991) · PubMed · Cited by 63
Antibiotics for prophylaxis of Plasmodium falciparum infections: in vitro activity of doxycycline against Senegalese isolates.
Pradines, B., Spiegel, A., Rogier, C., et al. (2000) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2000.62.82 · Cited by 63
Chondroitin sulfate of thrombomodulin is an adhesion receptor for Plasmodium falciparum-infected erythrocytes
Gysin, J., Pouvelle, B., Tonquèze, M. L., Edelman, L., & Boffa, M. (1997) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(97)00082-0 · Cited by 60
New tissue schizontocidal antimalarial drugs.
Davidson, D. E., Ager, A. L., Brown, J. L., et al. (1981) · PubMed · Cited by 59
Drug-induced haemolysis in glucose-6-phosphate dehydrogenase deficiency.
Chan, T., Todd, D., & Tso, S. C. (1976) · BMJ · doi:10.1136/bmj.2.6046.1227 · Cited by 59
Inhibition of Plasmodium falciparum dihydropteroate synthetase and growth in vitro by sulfa drugs
Zhang, Y., & Meshnick, S. (1991) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.35.2.267 · Cited by 59
Study of the efficacy of antimalarial drugs delivered inside targeted immunoliposomal nanovectors
Urbán, P., Estelrich, J., Adeva, A., Cortés, A., & Fernàndez‐Busquets, X. (2011) · Nanoscale Research Letters · doi:10.1186/1556-276x-6-620 · Cited by 59
A Randomized Trial of Artesunate-Mefloquine versus Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Mali
Sagara, I., Diallo, A. I., Koné, M., Coulibaly, M., Diawara, S. I., Guindo, O., Maiga, H., Niambele, M. B., Sissoko, M., Dicko, A., et al. (2008) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2008.79.655 · Cited by 59
Structure of a Plasmodium falciparum PfEMP1 rosetting domain reveals a role for the N-terminal segment in heparin-mediated rosette inhibition
Juillerat, A., Lewit‐Bentley, A., Guillotte-Blisnick, M., Gangnard, S., Hessel, A., Baron, B., Vigan-Womas, I., England, P., Mercereau‐Puijalon, O., & Bentley, G. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018692108 · Cited by 59
Neurological, cardiovascular and metabolic effects of mefloquine in healthy volunteers: a double-blind, placebo-controlled trial
Davis, T. M. E., Dembo, L. G., KAYE‐EDDIE, S. A., et al. (1996) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1996.04745.x · Cited by 58
Efficacy of sulfadoxine-pyrimethamine in Tanzania after two years as first-line drug for uncomplicated malaria: assessment protocol and implication for treatment policy strategies
Mugittu, K., Abdulla, S., Falk, N., Masanja, H., Felger, I., Mshinda, H., Beck, H., & Genton, B. (2005) · Malaria Journal · doi:10.1186/1475-2875-4-55 · Cited by 57
Targeting primaquine into liver using chylomicron emulsions for potential vivax malaria therapy
Dierling, A. M., & Cui, Z. (2005) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.07.015 · Cited by 57
A Low-Cost Microfluidic Chip for Rapid Genotyping of Malaria-Transmitting Mosquitoes
Liu, C.-C., Mauk, M., Hart, R., Bonizzoni, M., Yan, G., & Bau, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042222 · Cited by 57
Toxicity and side-effects of antimalarials in Africa: a critical review.
SALAKO, L. A. (1984) · PubMed · Cited by 56
Cytoskeletal and membrane remodelling during malaria parasite invasion of the human erythrocyte
Zuccala, E. S., & Baum, J. (2011) · British Journal of Haematology · doi:10.1111/j.1365-2141.2011.08766.x · Cited by 56
Functional drug targeting to erythrocytes in vivo using antibody bearing liposomes as drug vehicles
Agrawal, A., Singhal, A. K., & Gupta, C. M. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)91118-1 · Cited by 56
New Concepts in Treatment of Malaria with Malignant Tertian Cerebral Involvement
Smitskamp, H., & Fh, W. (1971) · BMJ · doi:10.1136/bmj.1.5751.714 · Cited by 56
Chloroquine/doxycycline combination versus chloroquine alone, and doxycycline alone for the treatment of Plasmodium falciparum and Plasmodium vivax malaria in northeastern Irian Jaya, Indonesia.
Taylor, W., Widjaja, H., Richie, T. L., et al. (2001) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2001.64.223 · Cited by 56
Long-circulating liposome-encapsulated ganciclovir enhances the efficacy of HSV-TK suicide gene therapy
Kajiwara, E., Kawano, K., Hattori, Y., et al. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.04.011 · Cited by 56
Biosensors as rapid diagnostic tests for tropical diseases
Teles, F., Tavira, L. A. P. D. T., & Fonseca, L. P. (2010) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2010.518405 · Cited by 55
Plasmodium falciparum:Molecular Background to Strain-Specific Rosette Disruption by Glycosaminoglycans and Sulfated Glycoconjugates
Barragán, A., Spillmann, D., Kremsner, P. G., Wahlgren, M., & Carlson, J. (1999) · Experimental Parasitology · doi:10.1006/expr.1998.4349 · Cited by 55
Chondroitin sulfate proteoglycan but not hyaluronic acid is the receptor for the adherence of Plasmodium falciparum-infected erythrocytes in human placenta, and infected red blood cell adherence up-regulates the receptor expression.
Muthusamy, A., Achur, R., Valiyaveettil, M., Botti, J. J., Taylor, D. W., Leke, R., & Gowda, D. (2007) · American Journal of Pathology · doi:10.2353/ajpath.2007.061238 · Cited by 54
An improved method for the in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes
Ghosh, A. K., Dinglasan, R. R., Ikadai, H., et al. (2010) · Malaria Journal · doi:10.1186/1475-2875-9-194 · Cited by 54
Evaluation of SPf66 malaria vaccine during a 22-month follow-up field trial in the Pacific coast of Colombia
Valero-Bernal, M. V. (1996) · Vaccine · doi:10.1016/s0264-410x(96)00070-9 · Cited by 54
Ophthalmological monitoring for hydroxychloroquine toxicity: a scientific review of available data
Silman, A. J., & Shipley, M. (1997) · Lara D. Veeken · doi:10.1093/rheumatology/36.5.599 · Cited by 54
The characteristics of anticoagulation by covalently immobilized heparin
Miura, Y., Aoyagi, S., Kusada, Y., et al. (1980) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820140508 · Cited by 53
A green fluorescent protein-based assay for determining gametocyte production in Plasmodium falciparum
DIXON, M., Peatey, C., Gardiner, D. L., et al. (2008) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2008.10.004 · Cited by 52
Physicochemical characterization and skin permeation of liposome formulations containing clindamycin phosphate
Shanmugam, S., Song, C.-K., Nagayya-Sriraman, S., et al. (2009) · Archives of Pharmacal Research · doi:10.1007/s12272-009-1713-0 · Cited by 52
Mutations in the Antifolate-Resistance-Associated Genes Dihydrofolate Reductase and Dihydropteroate Synthase in Plasmodium vivax Isolates from Malaria-Endemic Countries
Lu, F., Lim, C. S., Nam, D. H., et al. (2010) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2010.10-0004 · Cited by 50
Biological and Biochemical Characteristics of Cytoadhesion of Plasmodium falciparum -Infected Erythrocytes to Chondroitin-4-Sulfate
Pouvelle, B., Fusaı̈, T., Lépolard, C., & Gysin, J. (1998) · Infection and Immunity · doi:10.1128/iai.66.10.4950-4956.1998 · Cited by 50
A selective de-heparinizer filter made of new cross-linked polymers of a poly-amido-amine structure
Marchisio, M. A., Longo, T., & Ferruti, P. (1973) · Cellular and Molecular Life Sciences · doi:10.1007/bf01913274 · Cited by 49
In Vitro Generation of Plasmodium falciparum Ookinetes
Bounkeua, V., Li, F., & Vinetz, J. M. (2010) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2010.10-0433 · Cited by 49
Sulfated Glycoconjugates as Disrupters of Plasmodium Falciparum Erythrocyte Rosettes
Rogerson, S. J., Reeder, J. C., Al-Yaman, F. M., et al. (1994) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1994.51.198 · Cited by 49
Whole-Blood Immunoassay Facilitated by Gold Nanoshell–Conjugate Antibodies
Hirsch, L., Halas, N. J., & West, J. L. (2005) · Humana Press eBooks · doi:10.1385/1-59259-901-x:101 · Cited by 48
Anti-malarial drug formulations and novel delivery systems: A review
Murambiwa, P., Masola, B., Govender, T., et al. (2011) · Acta Tropica · doi:10.1016/j.actatropica.2011.03.005 · Cited by 48
Antibody‐mediated targeting of liposomes to red cells in vivo
Singhal, A. K., & Gupta, C. M. (1986) · FEBS Letters · doi:10.1016/0014-5793(86)80632-9 · Cited by 47
Detection of Malaria Infection via Latex Agglutination Assay
Polpanich, D., Tangboriboonrat, P., Elaı̈ssari, A., et al. (2007) · Analytical Chemistry · doi:10.1021/ac070502w · Cited by 47
Construction of nanoscale multicompartment liposomes for combinatory drug delivery
Al-Jamal, W. A. J., & Kostarelos, K. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.11.020 · Cited by 47
Antimalarial drugs – host targets (re)visited
Cunha‐Rodrigues, M., Prudêncio, M., Mota, M. M., & Haas, W. (2006) · Biotechnology Journal · doi:10.1002/biot.200500038 · Cited by 46
The reality of using primaquine
Burgoine, K. L., Bancone, G., & Nosten, F. H. (2010) · Malaria Journal · doi:10.1186/1475-2875-9-376 · Cited by 44
Structure–activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-d-xylulose 5-phosphate synthase
Mao, J., Eoh, H., He, R. L., Wang, Y., Wan, B., Franzblau, S. G., Crick, D. C., & Kozikowski, A. P. (2008) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2008.08.034 · Cited by 44
Vaccines against malaria – an update
Matuschewski, K., & Mueller, A. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05998.x · Cited by 43
Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali
Teketé, M., DJIMDÉ, A. A., Béavogui, A. H., et al. (2009) · Malaria Journal · doi:10.1186/1475-2875-8-34 · Cited by 43
A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1‐deoxy‐ d ‐xylulose 5‐phosphate synthase
Sauret-Gueto, S., Urós, E. M., Ibáñez, E., et al. (2006) · FEBS Letters · doi:10.1016/j.febslet.2005.12.092 · Cited by 43
Nasal in situ gel containing hydroxy propyl β-cyclodextrin inclusion complex of artemether: development and in vitro evaluation
Mahajan, H. S., Shah, S. K., & Surana, S. J. (2010) · Journal of Inclusion Phenomena and Macrocyclic Chemistry · doi:10.1007/s10847-010-9861-x · Cited by 43
Formulation design and in vivo antimalarial evaluation of lipid-based drug delivery systems for oral delivery of β-arteether
Memvanga, P. B., & Véronique Préat, A. (2012) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2012.05.004 · Cited by 43
Inhibition of Chondroitin-4-Sulfate-Specific Adhesion of Plasmodium falciparum -Infected Erythrocytes by Sulfated Polysaccharides
Andrews, K. T., Klatt, N., Adams, Y., Mischnick, P., & Schwartz‐Albiez, R. (2005) · Infection and Immunity · doi:10.1128/iai.73.7.4288-4294.2005 · Cited by 42
Plasmodium falciparum induces reorganization of host membrane proteins during intraerythrocytic growth
Parker, P. D., Tilley, L. M., & Klonis, N. (2003) · Blood · doi:10.1182/blood-2003-08-2692 · Cited by 42
Heparin in the Treatment of Cerebral Malaria
Munir, M., Tjandra, H., Rampengan, T. H., et al. (2021) · Paediatrica Indonesiana · doi:10.14238/pi20.1-2.1980.47-50 · Cited by 41
Psychosis with paranoid delusions after a therapeutic dose of mefloquine: a case report
Tran, T. M., Browning, J. A., & Dell, M. L. (2006) · Malaria Journal · doi:10.1186/1475-2875-5-74 · Cited by 41
Chloroquine containing liposomes in the chemotherapy of murine malaria
Peeters, P. A. M., Huiskamp, C. W. E. M., Eling, W. M. C., & Crommelin, D. J. A. (1989) · Parasitology · doi:10.1017/s003118200006145x · Cited by 41
Demonstration of specific binding of heparin to Plasmodium falciparum-infected vs. non-infected red blood cells by single-molecule force spectroscopy
Valle‐Delgado, J. J., Urbán, P., & Fernàndez‐Busquets, X. (2012) · Nanoscale · doi:10.1039/c2nr32821f · Cited by 41
Cerebral malaria in children. Comparative study between heparin, dexamethasone and placebo.
Rampengan, T. H. (1991) · PubMed · Cited by 39
Enhancing membrane disruption by targeting and multivalent presentation of antimicrobial peptides
Chamorro, C., Boerman, M. A., Arnusch, C. J., et al. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.04.004 · Cited by 38
In vivo evaluation of arteether liposomes
Bayomi, M. A., Al-Angary, A. A., Al‐Meshal, M. A., et al. (1998) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00182-3 · Cited by 38
MSP-1p42-specific antibodies affect growth and development of intra-erythrocytic parasites of Plasmodium falciparum
Bergmann‐Leitner, E. S., Duncan, E. H., & Angov, E. (2009) · Malaria Journal · doi:10.1186/1475-2875-8-183 · Cited by 38
Polymerase chain reaction–based tests for pan‐species and species‐specific detection of human Plasmodium parasites
Mahajan, B., Zheng, H., Pham, P. T., et al. (2012) · Transfusion · doi:10.1111/j.1537-2995.2011.03541.x · Cited by 37
The challenge of malaria eradication in the twenty-first century: Research linked to operations is the key
Breman, J. G., & Brandling-Bennett, A. D. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.12.003 · Cited by 36
A single‐molecule force spectroscopy nanosensor for the identification of new antibiotics and antimalarials
Sisquella, X., Pourcq, K. D., Alguacil, J., Robles, J., Sanz, F., Anselmetti, D., Imperial, S., & Fernàndez‐Busquets, X. (2010) · The FASEB Journal · doi:10.1096/fj.10-155507 · Cited by 35
A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of Chloroquine
Haynes, R. K., Cheu, K., Li, K., et al. (2011) · ChemMedChem · doi:10.1002/cmdc.201100184 · Cited by 35
Chlorproguanil–Dapsone–Artesunate versus Chlorproguanil–Dapsone: A Randomized, Double-Blind, Phase III Trial in African Children, Adolescents, and Adults with Uncomplicated Plasmodium falciparum Malaria
Tiono, A. B., Dicko, A., Ndububa, D. A., Agbenyega, T., Pitmang, S., Awobusuyi, J. O., Pamba, A., Duparc, S., Goh, L., Harrell, E., et al. (2009) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2009.09-0351 · Cited by 35
Artemether–lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania
Färnert, A., Ursing, J., Tolfvenstam, T., et al. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-176 · Cited by 35
Paul Ehrlich (1854-1915): man with the magic bullet.
Tan, S. Y., & Grimes, S. (2010) · PubMed · Cited by 35
Structural Basis for Binding of Plasmodium falciparum Erythrocyte Membrane Protein 1 to Chondroitin Sulfate and Placental Tissue and the Influence of Protein Polymorphisms on Binding Specificity
Beeson, J. G., Andrews, K. T., Boyle, M. J., Duffy, M. F., Choong, E. K., Byrne, T. J., Chesson, J. M., Lawson, A. M., & Chai, W. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700231200 · Cited by 34
The SPf66 Malaria Vaccine: What is the Evidence for Efficacy?
Graves, P., Gelband, H., & Garner, P. (1998) · Parasitology Today · doi:10.1016/s0169-4758(98)01242-3 · Cited by 32
Band 3 clustering promotes the exposure of neoantigens in Plasmodium falciparum-infected erythrocytes
Winograd, E., Prudhomme, J. G., & Sherman, I. W. (2005) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2005.03.013 · Cited by 32
Treatment with liposome-bound recombinant human tumor necrosis factor-alpha suppresses parasitemia and protects against Plasmodium berghei k173-induced experimental cerebral malaria in mice.
Postma, N. S., Crommelin, D. J. A., Eling, W. M. C., et al. (1999) · PubMed · Cited by 32
Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies
Bonnet, M., van den Broek, I., Herp, M. V., et al. (2009) · Malaria Journal · doi:10.1186/1475-2875-8-192 · Cited by 32
Disruption of Rosetting in Plasmodium falciparum Malaria with Chemically Modified Heparin and Low Molecular Weight Derivatives Possessing Reduced Anticoagulant and Other Serine Protease Inhibition Activities
Skidmore, M. A., Dumax-Vorzet, A. F., Guimond, S. E., et al. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm701337t · Cited by 31
Artemether-Lumefantrine: An Option for Malaria
Stover, K. R., King, S. T., & Robinson, J. (2012) · Annals of Pharmacotherapy · doi:10.1345/aph.1q539 · Cited by 31
M alaria Intervention Policies and Pharmaceutical Nanotechnology as a Potential Tool for Malaria Management
Kuntworbe, N., Martini, N. D., Shaw, J., & Al‐Kassas, R. (2012) · Drug Development Research · doi:10.1002/ddr.21010 · Cited by 30
Free-flow electrophoresis for the separation of malaria infected and uninfected mouse erythrocytes and for the isolation of free parasites (Plasmodium vinckei): A new rapid technique for the liberation of malaria parasites from their host cells
Heidrich, H., Rüssmann, L., Bayer, B., et al. (1979) · Parasitology Research · doi:10.1007/bf01951339 · Cited by 30
Chemical Force Microscopy with Active Enzymes
Fiorini, M. T., McKendry, R. A., Cooper, M. A., et al. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)76215-7 · Cited by 30
Pharmacovigilance of artemether-lumefantrine in pregnant women followed until delivery in Rwanda
Rulisa, S., Kaligirwa, N., Agaba, S., Karema, C., Mens, P. F., & de Vries, P. J. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-225 · Cited by 30
Vaccines for preventing malaria
Graves, P. M., & Gelband, H. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000129.pub2 · Cited by 29
Plasmodium Cell Biology Should Inform Strategies Used In The Development Of Antimalarial Transmission-Blocking Drugs
Delves, M. J. (2012) · Future Medicinal Chemistry · doi:10.4155/fmc.12.182 · Cited by 29
The First Cadmium-Specific Enzyme
Strasdeit, H. (2001) · Angewandte Chemie International Edition · doi:10.1002/1521-3773(20010216)40:4 · Cited by 29
Malaria: deploying a candidate vaccine (RTS,S/AS02A) for an old scourge of humankind.
Alonso, P. L. (2006) · PubMed · Cited by 29
Liposomes as a Drug Delivery System: Optimization Studies
Gregoriadis, G. C. (1988) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-7908-9_12 · Cited by 28
Biochemical and biophysical characterisation of DBL1α1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum
Juillerat, A., Igonet, S., Vigan-Womas, I., Guillotte-Blisnick, M., Gangnard, S., Faure, G., Baron, B., Raynal, B. D. E., Mercereau‐Puijalon, O., & Bentley, G. A. (2010) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2009.12.008 · Cited by 28
Sulfated glycoconjugates enhance CD36-dependent adhesion ofPlasmodium falciparum–infected erythrocytes to human microvascular endothelial cells
McCormick, C. J., Newbold, C., & Berendt, A. R. (2000) · Blood · doi:10.1182/blood.v96.1.327 · Cited by 27
Transient transfection of Plasmodium vivax blood-stage parasites.
Pfahler, J. M., Galinski, M., Barnwell, J., & Lanzer, M. (2006) · Methods in molecular biology · doi:10.1016/j.molbiopara.2006.03.018 · Cited by 27
Liposomes Incorporating a Plasmodium Amino Acid Sequence Target Heparan Sulfate Binding Sites in Liver
Robertson, R. T., Baratta, J. L., Haynes, S. M., & Longmuir, K. J. (2007) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21211 · Cited by 26
The transport of chloroquine across human erythrocyte membranes is mediated by a simple symmetric carrier
Yayon, A., & Ginsburg, H. (1982) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(82)90113-4 · Cited by 26
New Chemotherapeutic Strategies Against Malaria, Leishmaniasis and Trypanosomiases
Zucca, M., Scutera, S., & Savoia, D. (2013) · Current Medicinal Chemistry · doi:10.2174/0929867311320040003 · Cited by 26
Plasmodium berghei ookinete formation in vitro
Yoeli, M., & Upmanis, R. S. (1968) · Experimental Parasitology · doi:10.1016/0014-4894(68)90085-4 · Cited by 25
Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India
Gargano, N., Ubben, D., Tommasini, S., Bacchieri, A., Corsi, M., Bhattacharyya, P. C., Rao, B. H. K., Dubashi, N., Dev, V., Ghosh, S. K., et al. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-233 · Cited by 25
The ‘Do Unto Others’ Malaria Vaccine
Vogel, G. (2010) · Science · doi:10.1126/science.328.5980.847 · Cited by 24
Cardiotoxicity after low-dose chloroquine antimalarial therapy
Fragasso, G., Sanvito, F., Baratto, F., et al. (2009) · Heart and Vessels · doi:10.1007/s00380-008-1144-8 · Cited by 23
Arginine vasopressin mediates the chloroquine induced increase in renal sodium excretion
Musabayane, C. T., Windle, R. J., Forsling, M. L., et al. (1996) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.1996.d01-81.x · Cited by 23
Synthetic vaccine update: Applying lessons learned from recent SPf66 malarial vaccine physicochemical, structural and immunological characterization
Bermúdez, A., Reyes, C., Guzmán, F., et al. (2007) · Vaccine · doi:10.1016/j.vaccine.2007.03.016 · Cited by 21
Plasmodium vinckei:Optimization of Desferrioxamine B Delivery in the Treatment of Murine Malaria
Postma, N. S., Hermsen, C. C., Zuidema, J., & Eling, W. M. C. (1998) · Experimental Parasitology · doi:10.1006/expr.1998.4282 · Cited by 20
Merozoite surface protein-1 epitopes recognized by antibodies that inhibit Plasmodium falciparum merozoite dispersal
Lyon, J. A., Carter, J. M., Thomas, A. W., et al. (1997) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(97)00155-2 · Cited by 19
Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine
Adjei, G. O., Oduro-Boatey, C., Rodrigues, O. P., Hoegberg, L. C. G., Alifrangis, M., Kurtzhals, J. A. L., & Goka, B. Q. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-420 · Cited by 19
In vitroandin vivoevaluation of albumin-encapsulated primaquine diphosphate prepared by nebulization into heated oil
Green, M. D., D’Souza, M. J., Holbrook, J. M., et al. (2004) · Journal of Microencapsulation · doi:10.1080/02652040410001729232 · Cited by 19
Estimating Kinetic and Thermodynamic Parameters from Single Molecule Enzyme−Inhibitor Interactions
Porter-Peden, L., Kamper, S. G., Wal, M. V., et al. (2008) · Langmuir · doi:10.1021/la801477a · Cited by 18
Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria
Malderen, C. V., Geertruyden, J. V., Machevo, S., González, R., Bassat, Q., Talisuna, A. O., Yeka, A., Nabasumba, C., Piola, P., Atwine, D., et al. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-139 · Cited by 18
Mefloquine: the benefits outweigh the risks
Winstanley, P. (1996) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1996.04754.x · Cited by 17
Mapping enzymatic functionalities of mannuronan C-5 epimerases and their modular units by dynamic force spectroscopy
Sletmoen, M., Skjåk‐Bræk, G., & Stokke, B. T. (2005) · Carbohydrate Research · doi:10.1016/j.carres.2005.09.020 · Cited by 16
Efficacy of artemether-lumefantrine as a treatment for uncomplicated Plasmodium vivax malaria in eastern Sudan
Abdallah, T. M., Ali, A. A. A., Bakri, M., et al. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-404 · Cited by 16
Optimized In Vitro Production of Plasmodium vivax Ookinetes
McClean, C. M., Alvarado, H. G., Neyra, V., et al. (2010) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2010.10-0195 · Cited by 15
Artesunate/Amodiaquine Malaria Treatment for Equatorial Guinea (Central Africa)
Charle‐Cuéllar, P., Berzosa, P. J., de Lucio, A., et al. (2013) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.12-0290 · Cited by 15
Investigating the Specific Interactions between Carbonic Anhydrase and a Sulfonamide Inhibitor by Single-Molecule Force Spectroscopy
Kamper, S. G., Porter-Peden, L., Blankespoor, R. L., et al. (2007) · Langmuir · doi:10.1021/la702148v · Cited by 14
Microfabricated tip arrays for improving force measurements
Green, J. D., Novoradovsky, A., Park, D., et al. (1999) · Applied Physics Letters · doi:10.1063/1.123590 · Cited by 13
Drug Delivery in the BME Curricula
Saltzman, W. M., & Desai, T. A. (2006) · Annals of Biomedical Engineering · doi:10.1007/s10439-005-9020-5 · Cited by 12
Toxicity Related to Chloroquine Treatment of Resistant Vivax Malaria
Davis, T. M. E., Syed, D. A., Ilett, K. F., et al. (2003) · Annals of Pharmacotherapy · doi:10.1345/aph.1c311 · Cited by 12
Heparin-Functionalized Nanocapsules: Enabling Targeted Delivery of Antimalarial Drugs
Fernàndez‐Busquets, X. (2013) · Future Medicinal Chemistry · doi:10.4155/fmc.13.53 · Cited by 10
Force Spectroscopy between Acetylcholine and Single Acetylcholinesterase Molecules and the Effects of Inhibitors and Reactivators Studied by Atomic Force Microscopy
Yingge, Z., Bai, C., Chen, W., et al. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)29599-9 · Cited by 10
Developmental Stage- and Cell Cycle Number-Dependent Changes in Characteristics of Plasmodium falciparum -Infected Erythrocyte Adherence to Placental Chondroitin-4-Sulfate Proteoglycan
Madhunapantula, S. V., Achur, R. N., & Gowda, D. C. (2007) · Infection and Immunity · doi:10.1128/iai.00478-07 · Cited by 9
Neurological, cardiovascular and metabolic effects of mefloquine in healthy volunteers: a double-blind, placebo-controlled trial.
Evans, S., & Pc, W. (1997) · PubMed · Cited by 8
Sustained release implants of chloroquine phosphate for possible use in chemoprophylaxis of malaria.
Saparia, B., Solanki, A., & Murthy, R. (2001) · PubMed · Cited by 8
Actionable theranostics for global maternal health: a focus on HIV and malaria
Madadi, P., Enato, E. F. O., & Walfisch, A. (2012) · Expert Review of Molecular Diagnostics · doi:10.1586/erm.12.118 · Cited by 2

Sorted by citations

Nanotechnology approaches for global infectious diseases
Kirtane, A. R., Verma, M., Karandikar, P., Furin, J., Langer, R., & Traverso, G. (2021) · Nature Nanotechnology · doi:10.1038/s41565-021-00866-8 · Cited by 520
Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery
Marques, J., Valle-Delgado, J. J., Urbán, P., Baró, E., Prohens, R., Mayor, A., Cisteró, P., Delves, M., Sinden, R. E., Grandfils, C., et al. (2017) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2016.09.010 · Cited by 64

See all 39

Authors: Urban, P., & Fernandez-Busquets, X.
Venue: Current Medicinal Chemistry
Publisher: Bentham Science Publishers Ltd.
Published: 2014-01-31
Volume: 21
Issue: 5
Pages: 605-629
ISSN: 0929-8673 (ISSN-L)
DOI: 10.2174/09298673113206660292
OpenAlex: W2325546659
Cited by: 39
References: 313
Citations by year: 2026: 1 · 2025: 2 · 2024: 6 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 4 · 2015: 2 · 2014: 3
FWCI: 4.29
Type: journal article
Language: en
Open access: closed
Locations: Current Medicinal Chemistry (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Pharmacology and Nanomedicine Research
Keywords: malaria, Plasmodium, nanomedicine, targeted drug delivery, nanocapsules, antimalarial drugs, single-molecule manipulation, drug discovery, malaria diagnosis, microfluidics, parasite developmental stages, developing countries
MeSH terms: Amino Alcohols, Antimalarials, Drug Carriers, Humans, Malaria, Plasmodium, Quinolines, Drug Design, Dendrimers, Nanomedicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nanomedicine Against Malaria

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks