The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Purinergic Receptors and Pain
Abstract
There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, of ATP storage, release and ectoenzymatic breakdown and of the current classification of receptor subtypes for purines and pyrimidines. The review then focuses on purinergic mechanosensory transduction involved in visceral, cutaneous and musculoskeletal nociception and on the roles played by P2X-(3), P2Y(2/3), P2X(4), P2X(7) and P2Y(12) receptors in neuropathic and inflammatory pain. Current developments of compounds for the therapeutic treatment of both visceral and neuropathic pain are discussed.
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Citations
Cites
Molecular Physiology of P2X Receptors
North, R. A. (2002) · Physiological Reviews · doi:10.1152/physrev.00015.2002 · Cited by 2,919
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
Coull, J. A. M., Beggs, S., Boudreau, D., Boivin, D., Tsuda, M., Inoue, K., Gravel, C., Salter, M. W., & De Koninck, Y. (2005) · Nature · doi:10.1038/nature04223 · Cited by 1,965
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Haynes, S. E., Hollopeter, G., Yang, G., Kurpius, D., Dailey, M. E., Gan, W.-B., & Julius, D. (2006) · Nature Neuroscience · doi:10.1038/nn1805 · Cited by 1,542
Adenosine Receptors as Therapeutic Targets
Jacobson, K. A., & Gao, Z.-G. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd1983 · Cited by 1,431 · cited 1×
“Specific agonists and antagonists are available for the P1 receptor subtypes [54].”
BackgroundCellular localization of P2X7 receptor mRNA in the rat brain
Yu, Y., Ugawa, S., Ueda, T., Ishida, Y., Inoue, K., Kyaw Nyunt, A., Umemura, A., Mase, M., Yamada, K., & Shimada, S. (2008) · Brain Research · doi:10.1016/j.brainres.2007.11.064 · Cited by 132
Properties of the pore‐forming P2X7 purinoceptor in mouse NTW8 microglial cells
Chessell, I. P., Michel, A. D., & Humphrey, P. P. A. (1997) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0701278 · Cited by 126
Cited by
P2X Receptors in Health and Disease
Burnstock, G., & Kennedy, C. (2011) · Advances in Pharmacology · doi:10.1016/b978-0-12-385526-8.00011-4 · Cited by 213
Self-citationThe postsynaptic function of type II cochlear afferents
Weisz, C., Glowatzki, E., & Fuchs, P. (2009) · Nature · doi:10.1038/nature08487 · Cited by 160
Metadata
- Authors
- Burnstock, G.
- Venue
- Current Pharmaceutical Design
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2009-05-01
- Volume
- 15
- Issue
- 15
- Pages
- 1717-1735
- ISSN
- 1381-6128 (ISSN-L)
- OpenAlex
- W2073451266
- Cited by
- 195
- References
- 6
- FWCI
- 11.59
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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