Cellular localization of P2X7 receptor mRNA in the rat brain

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P2X7 receptor inhibition improves recovery after spinal cord injury

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ADP and AMP Induce Interleukin-1β Release from Microglial Cells through Activation of ATP-Primed P2X7 Receptor Channels

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Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release

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Activation of Presynaptic P2X7-Like Receptors Depresses Mossy Fiber–CA3 Synaptic Transmission through p38 Mitogen-Activated Protein Kinase

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P2 receptor modulation and cytotoxic function in cultured CNS neurons

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Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection

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P2X7 Receptors in Rat Brain: Presence in Synaptic Terminals and Granule Cells

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Interaction of ATP and Calcium on the Rat Mast Cell: Effect on Histamine Release

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In situ hybridization evidence for the coexistence of ASIC and TRPV1 within rat single sensory neurons

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ATP stimulation of P2X7 receptors activates three different ionic conductances on cultured mouse Schwann cells

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Physiology of Microglia

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The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

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Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

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The P2X ₇ Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X ₇ R Pore

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P2X7 Receptors: Channels, Pores and More

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Altered P2X7‐receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration

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Purinoceptors on Neuroglia

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Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

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Purinergic Receptors and Pain

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Adenosine and ATP Receptors in the Brain

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P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia

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Neuronal P2X7 Receptors Revisited: Do They Really Exist?

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Purinergic Mechanisms and Pain

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Neuroglial Transmission

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Chronic Pain States: Pharmacological Strategies to Restore Diminished Inhibitory Spinal Pain Control

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The P2X7 Receptor: Central Hub of Brain Diseases

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Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy

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Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology

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Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology

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Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis

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P2X7 Receptor Signaling in Stress and Depression

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The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis

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Purinergic mechanisms and pain—An update

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Involvement of microglial P2X7 receptors and downstream signaling pathways in long-term potentiation of spinal nociceptive responses

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Astrocyte-Mediated Ischemic Tolerance

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Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

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Spinal P2X7 receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model

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Impaired Interleukin-1β and c-Fos Expression in the Hippocampus Is Associated with a Spatial Memory Deficit in P2X7 Receptor-Deficient Mice

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Involvement of Spinal Microglial P2X7 Receptor in Generation of Tolerance to Morphine Analgesia in Rats

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P2X7 receptor antagonists: a patent review (2010–2015)

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NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation by 17β‐Estradiol

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Role of P2X7 Receptor-Mediated IL-18/IL-18R Signaling in Morphine Tolerance: Multiple Glial-Neuronal Dialogues in the Rat Spinal Cord

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Physiological and pathological functions of P2X7 receptor in the spinal cord

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Emerging role of P2X7 receptors in CNS health and disease

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Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response

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P2X7 Receptors in Oligodendrocytes: A Novel Target for Neuroprotection

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Cellular and molecular mechanisms driving neuropathic pain: recent advancements and challenges

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Downregulation of P2X7receptor expression in rat oligodendrocyte precursor cells after hypoxia ischemia

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P2X7 Receptor Inhibition Interrupts the Progression of Seizures in Immature Rats and Reduces Hippocampal Damage

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A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334

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Central sensitization of nociceptive neurons in rat medullary dorsal horn involves purinergic P2X7 receptors

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Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse

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Involvement of RVM-expressed P2X7 receptor in bone cancer pain: Mechanism of descending facilitation

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P2X7 receptor in multifaceted cellular signalling and its relevance as a potential therapeutic target in different diseases

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ATP‐P2X7receptor signaling controls basal and TNFα‐stimulated glial cell proliferation

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Receptor localization, native tissue binding and ex vivo occupancy for centrally penetrant P2X7 antagonists in the rat

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P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus

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Administration of an antagonist of P2X7 receptor to EAE rats prevents a decrease of expression of claudin-5 in cerebral capillaries

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P2X receptors in neuroglia

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Ependymal cells along the lateral ventricle express functional P2X7 receptors

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Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death

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Membrane compartments and purinergic signalling: P2X receptors in neurodegenerative and neuroinflammatory events

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P2 receptor interaction and signalling cascades in neuroprotection

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Electroacupuncture ameliorating post-stroke cognitive impairments via inhibition of peri-infarct astroglial and microglial/macrophage P2 purinoceptors-mediated neuroinflammation and hyperplasia

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Microglia‐derived purines modulate mossy fibre synaptic transmission and plasticity through P2X4 and A1 receptors

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Purinergic signalling at the plasma membrane: a multipurpose and multidirectional mode to deal with amyotrophic lateral sclerosis and multiple sclerosis

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Microglial P2 Purinergic Receptor and Immunomodulatory Gene Transcripts Vary By Region, Sex, and Age in the Healthy Mouse CNS

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MiR-187-3p mimic alleviates ischemia-reperfusion-induced pain hypersensitivity through inhibiting spinal P2X7R and subsequent mature IL-1β release in mice

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Purinergic Receptors in Basal Ganglia Diseases: Shared Molecular Mechanisms between Huntington’s and Parkinson’s Disease

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regenerative-loop potentiation of glutamate synaptic transmission by microglia and astrocytes

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Neonatal Maternal Deprivation Enhances Presynaptic P2X7 Receptor Transmission in Insular Cortex in an Adult Rat Model of Visceral Hypersensitivity

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P2X7 Receptor Inhibition Increases CNTF in the Subventricular Zone, But Not Neurogenesis or Neuroprotection After Stroke in Adult Mice

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Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors

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Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X7-ROS-ASK1-p38 Axis in Microglial Cell Lines

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Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22

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Oxidative phosphorylation in HIV-1 infection: impacts on cellular metabolism and immune function

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P2X7 receptors in cerebral ischemia

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P2X7 Receptor: an Emerging Target in Alzheimer’s Disease

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Purinergic signaling in cognitive impairment and neuropsychiatric symptoms of Alzheimer's disease

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Purinergic signalling in a latent stem cell niche of the rat spinal cord

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Purinergic-associated immune responses in neurodegenerative diseases

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Characterization of the Novel P2X7 Receptor Radioligand [3H]JNJ-64413739 in Human Brain Tissue

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Intrinsic organization of the corpus callosum

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Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development

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Indispensable role of factor for adipocyte differentiation 104 (fad104) in lung maturation

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Estrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection.

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Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs

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P2RX7 in Dopaminergic Neurons of Ventral Periaqueductal Gray Mediates HTWP Acupuncture-Induced Consciousness in Traumatic Brain Injury

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P2X7 receptor activation mediates superoxide dismutase 1 (SOD1) release from murine NSC-34 motor neurons

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P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases

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Increase of intracellular Ca2+by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat

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D-serine in the midbrain periaqueductal gray contributes to morphine tolerance in rats

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Alterations of Purinergic Receptors Levels and Their Involvement in the Glial Cell Morphology in a Pre-Clinical Model of Autism Spectrum Disorders

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Activation of P2X7 receptors in the midbrain periaqueductal gray of rats facilitates morphine tolerance

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P2X7 purinergic receptor modulates dentate gyrus excitatory neurotransmission and alleviates schizophrenia-like symptoms in mouse

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P2X7 receptor activation awakes a dormant stem cell niche in the adult spinal cord

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Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis

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Purinergic and extracellular vesicle signaling in alcohol-induced blood–brain barrier breakdown and neuroimmune activation

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The role of extracellular ATP and P2X receptors in the pathogenesis of HIV-1

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A patent review of P2X7 receptor antagonists to treat inflammatory diseases (2018–present)

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Upregulation of the P2X7 receptor after cryogenic injury to rat brain

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Contribution of the spinal microglia to bee venom-induced inflammatory pain in conscious rats

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P2X7 receptor knockout mice display less aggressive biting behaviour correlating with increased brain activation in the piriform cortex

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Druggable targets for Parkinson’s disease: transcriptomics based Mendelian randomization study

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Tissue distribution of the P2X7 receptor

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Localization of P2X7 receptor immunoreactivity in the dorsal root ganglia of guinea pig

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p75NTR immunoreactivity in the rat dentate gyrus is mostly within presynaptic profiles but is also found in some astrocytic and postsynaptic profiles

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Neuronal P2X₇Receptors Are Targeted to Presynaptic Terminals in the Central and Peripheral Nervous Systems

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