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A Presenilin 1 Mutation Associated with Familial Frontotemporal Dementia Inhibits γ-Secretase Cleavage of APP and Notch

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Quantitative assessment of possible age-related change in synaptic numbers in the human frontal cortex

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Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

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Human apolipoprotein E4 accelerates β‐amyloid deposition in APPsw transgenic mouse brain

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Macrophage-Mediated Degradation of β-Amyloid via an Apolipoprotein E Isoform-Dependent Mechanism

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Modulation of Cell Death by Mouse Genotype: Differential Vulnerability to Excitatory Amino Acid-Induced Lesions

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Caspase-Mediated Degeneration in Alzheimer's Disease

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The proteins BACE1 and BACE2 and β-secretase activity in normal and Alzheimer's disease brain

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Expression of APP in Brains of Transgenic Mice Containing the Entire Human APP Gene

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Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death

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Management and design of the maintenance of sam mouse strains: an animal model for accelerated senescence and age-associated disorders

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Formation of Tau Inclusions in Knock-in Mice with Familial Alzheimer Disease (FAD) Mutation of Presenilin 1 (PS1)

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Oral Treatment with a γ-Secretase Inhibitor Improves Long-Term Potentiation in a Mouse Model of Alzheimer's Disease

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A polymorphism of the interleukin-1 beta gene at position +3953 influences progression and neuro-pathological hallmarks of Alzheimer’s disease

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Frontotemporal dementia and tauopathy

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Transgenic Mouse Models of Tauopathy in Drug Discovery

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Behavioral deficits in APPV717F transgenic mice decient for the apolipoprotein E gene

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Genetically Altering Aβ Distribution from the Brain to the Vasculature Ameliorates Tau Pathology

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Apolipoprotein E alters the processing of the β-amyloid precursor protein in APPV717F transgenic mice

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EARLY-ONSET ALZHEIMERS-DISEASE CAUSED BY MUTATIONS AT CODON-717 OF THE BETA-AMYLOID PRECURSOR PROTEIN GENE

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Alternative transcripts of presenilin-1 associated with frontotemporal dementia

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Reduction of amyloid β-peptide accumulation in Tg2576 transgenic mice by oral vaccination

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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

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Tau Filament Formation and Associative Memory Deficit in Aged Mice Expressing Mutant (R406W) Human Tau

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A new era for understanding amyloid structures and disease

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The case for rejecting the amyloid cascade hypothesis

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Transcription factor-mediated differentiation of human iPSCs into neurons

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Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease.

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Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent

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Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis

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