Venoms and Isolated Toxins from Snakes of Medical Impact in the Northeast Argentina: State of the Art. Potential Pharmacological Applications

Purification and properties

Cox, B. M., Opheim, K. E., Teschemacher, H., & D, A. G. M. (1975) · Life Sciences · doi:10.1016/0024-3205(75)90272-6 · Cited by 1,708 · see citing works

The venomous reptiles of the Western Hemisphere

(2005) · Choice Reviews Online · doi:10.5860/choice.42-4027 · Cited by 876 · see citing works

Snake venom variability: methods of study, results and interpretation

Chippaux, J., Williams, V. K., & White, J. (1991) · Toxicon · doi:10.1016/0041-0101(91)90116-9 · Cited by 754 · see citing works

Snakebite envenoming

Gutiérrez, J., Calvete, J., Habib, A., Harrison, R., Williams, D. J., & Warrell, D. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.63 · Cited by 752 · see citing works

Snake venoms and the hemostatic system

Markland, F. S. (1998) · Toxicon · doi:10.1016/s0041-0101(98)00126-3 · Cited by 703 · see citing works

Skeletal muscle degeneration induced by venom phospholipases A2: insights into the mechanisms of local and systemic myotoxicity

Gutiérrez, J. M., & Ownby, C. L. (2003) · Toxicon · doi:10.1016/j.toxicon.2003.11.005 · Cited by 443 · see citing works

Snake venom components and their applications in biomedicine

Koh, D., Armugam, A., & Jeyaseelan, K. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6315-0 · Cited by 362 · see citing works

Symptomatology, Pathology, and Treatment of Snake Bites in South America

ROSENFELD, G. (1971) · Elsevier eBooks · doi:10.1016/b978-0-12-138902-4.50021-0 · Cited by 310 · see citing works

Skeletal muscle regeneration

Allbrook, D. B. (1981) · Muscle & Nerve · doi:10.1002/mus.880040311 · Cited by 266 · see citing works

Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases

Escalante, T., Rucavado, A., Fox, J. W., & Gutiérrez, J. M. (2011) · Journal of Proteomics · doi:10.1016/j.jprot.2011.03.026 · Cited by 245 · see citing works

Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America

Calvete, J. J., Sanz, L., Cid, P., de la Torre, P., Flores-Dı́az, M., Santos, M., Borges, A., Bremo, A., Angulo, Y., Lomonte, B., et al. (2009) · Journal of Proteome Research · doi:10.1021/pr9008749 · Cited by 243 · see citing works

Structural domains in venom proteins: Evidence that metalloproteinases and nonenzymatic platelet aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor

Kini, R. M., & Evans, H. J. (1992) · Toxicon · doi:10.1016/0041-0101(92)90869-7 · Cited by 237 · see citing works

Myotoxic components of snake venoms: Their biochemical and biological activities

Mebs, D., & Ownby, C. L. (1990) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(90)90081-c · Cited by 219 · see citing works

Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming

Gutiérrez, J. M., Lomonte, B., León, G., Alape‐Girón, A., Flores-Dı́az, M., Sanz, L., Angulo, Y., & Calvete, J. J. (2009) · Journal of Proteomics · doi:10.1016/j.jprot.2009.01.008 · Cited by 212 · see citing works

Snake venomics and antivenomics of Crotalus durissus subspecies from Brazil: Assessment of geographic variation and its implication on snakebite management

Boldrini-França, J., Corrêa-Netto, C., Silva, M. M. S., Rodrigues, R. S., Torre, P. D. L., Pérez, A., Soares, A. M., Zingali, R. B., Nogueira, R. A., Rodrigues, V. D. M., et al. (2010) · Journal of Proteomics · doi:10.1016/j.jprot.2010.06.001 · Cited by 203 · see citing works

Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering

Calvete, J. J., Moreno-Murciano, P., Theakston, R. D. G., et al. (2003) · Biochemical Journal · doi:10.1042/bj20021739 · Cited by 199 · see citing works

Myonecrosis, myoglobinuria and acute renal failure induced by south american rattlesnake (Crotalus durissus terrificus) envenomation in brazil

Azevedo-Marques, M. M., Cupo, P., Coimbra, T. M., Hering, S. E., Rossi, M. A., & Laure, C. J. (1985) · Toxicon · doi:10.1016/0041-0101(85)90367-8 · Cited by 170 · see citing works

Interspecific variation in venom composition and toxicity of Brazilian snakes from Bothrops genus

Queiroz, G. P., Pessoa, L. A., Portaro, F. C. V., Furtado, M. F., & Tambourgi, D. V. (2008) · Toxicon · doi:10.1016/j.toxicon.2008.10.002 · Cited by 157 · see citing works

Crotoxin, a phospholipase A2 neurotoxin from the South American rattlesnake Crotalus durissus terrificus: purification of several isoforms and comparison of their molecular structure and of their biological activities

Faure, G., & Bon, C. (1988) · Biochemistry · doi:10.1021/bi00402a036 · Cited by 155 · see citing works

Biological activities of venoms from South American snakes

Sánchez, E. F., Freitas, T. V., Ferreira-Alves, D. L., et al. (1992) · Toxicon · doi:10.1016/0041-0101(92)90505-y · Cited by 154 · see citing works

Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper

Gutiérrez, J. M., Ownby, C. L., & Odell, G. V. (1984) · Experimental and Molecular Pathology · doi:10.1016/0014-4800(84)90054-6 · Cited by 144 · see citing works

Fractionation of Sakishima-habu (Trimeresurus elegans) Venom and Lethal, Hemorrhagic, and Edema-Forming Activities of the Fractions

Yamakawa, M., Nozaki, M., & HOKAMA, Z. (1976) · Springer eBooks · doi:10.1007/978-1-4684-0886-7_10 · Cited by 144 · see citing works

Platelet aggregation and antibacterial effects of an l-amino acid oxidase purified from Bothrops alternatus snake venom

Stábeli, R. G., Marcussi, S., Carlos, G. B., Pietro, R. C. L. R., Selistre-de-Araújo, H. S., Giglio, J. R., Oliveira, E. B., & Soares, A. M. (2004) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2004.03.049 · Cited by 139 · see citing works

A brief review of the scientific history of several lesser-known snake venom proteins: l-amino acid oxidases, hyaluronidases and phosphodiesterases

Fox, J. W. (2012) · Toxicon · doi:10.1016/j.toxicon.2012.09.009 · Cited by 124 · see citing works

Snake species of the world : a taxonomic and geographic reference. Vol. 1.

McDiarmid, R. W., Campbell, J. A., & Touré, T. A. (1999) · Cited by 118 · see citing works

Structural and functional characterization of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 from Bothrops jararacussu snake venom

Andrião-Escarso, S. H., Soares, A. M., Fontes, M. R. M., et al. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01210-8 · Cited by 113 · see citing works

Platelet Aggregation and Antibacterial Effects of an L‐Amino Acid Oxidase Purified from Bothrops alternatus Snake Venom.

Stábeli, R. G., Marcussi, S., Carlos, G. B., Pietro, R. C. L. R., Selistre-de-Araújo, H. S., Giglio, J. R., Oliveira, E. B., & Soares, A. M. (2004) · ChemInform · doi:10.1002/chin.200436208 · Cited by 111 · see citing works

Comparison of the biological activities in venoms from three subspecies of the South American rattlesnake (Crotalus durissus terrificus, C. durissus cascavella and C. durissus collilineatus)

Santoro, M. L., Sousa-e-Silva, M. C. C., Gonçalves, L. R. C., et al. (1999) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/s0742-8413(98)10079-8 · Cited by 99 · see citing works

Proteome analysis of snake venom toxins: pharmacological insights

Georgieva, D. N., Arni, R. K., & Betzel, C. (2008) · Expert Review of Proteomics · doi:10.1586/14789450.5.6.787 · Cited by 94 · see citing works

The analgesic activity of crotamine, a neurotoxin from Crotalus durissus terrificus (South American rattlesnake) venom: A biochemical and pharmacological study

Mancin, A. C., Soares, A. M., Andrião-Escarso, S. H., et al. (1998) · Toxicon · doi:10.1016/s0041-0101(98)00117-2 · Cited by 94 · see citing works

Epidemiologia e quadro clínico do acidente por cascavel sul-americana (Crotalus durissus)

Jorge, M. T., & Ribeiro, L. A. (1992) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46651992000400013 · Cited by 90 · see citing works

Evidence for heterogeneous forms of the snake venom metalloproteinase jararhagin: a factor contributing to snake venom variability

Moura-da-Silva, A. M., Della-Casa, M. S., David, A. S., Assakura, M. T., Butera, D., Lebrun, I., Shannon, J. D., Serrano, S. M. T., & Fox, J. W. (2002) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(02)00598-2 · Cited by 87 · see citing works

A comparative study of biological activities of crotoxin and CB fraction of venoms from Crotalus durissus terrificus, Crotalus durissus cascavella and Crotalus durissus collilineatus

Rangel-Santos, A., dos-Santos, E. C., Lopes‐Ferreira, M., et al. (2004) · Toxicon · doi:10.1016/j.toxicon.2004.03.011 · Cited by 85 · see citing works

Chemical and functional homology of myotoxin a from prairie rattlesnake venom and crotamine from south american rattlesnake venom

Cameron, D. L., & Tu, A. T. (1978) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(78)90457-9 · Cited by 85 · see citing works

The Venomics of Bothrops alternatus is a Pool of Acidic Proteins with Predominant Hemorrhagic and Coagulopathic Activities

Öhler, M., Georgieva, D. N., Seifert, J., von Bergen�, M., Arni, R. K., Genov, N. C., & Betzel, C. (2010) · Journal of Proteome Research · doi:10.1021/pr901128x · Cited by 81 · see citing works

Venoms to Drugs

(2015) · RSC drug discovery/RSC drug discovery series · doi:10.1039/9781849737876 · Cited by 79 · see citing works

Synergistic strategies of predominant toxins in snake venoms

Xiong, S., & Huang, C. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2018.02.004 · Cited by 78 · see citing works

Isolation and Preliminary Enzymatic Characterization of a Novel PLA2 from Crotalus durissus collilineatus Venom

Ponce-Soto, L. A., Toyama, M. H., Hyslop, S., Novello, J. C., & Marangoni, S. (2002) · Journal of Protein Chemistry · doi:10.1023/a:1015332314389 · Cited by 75 · see citing works

Venomous snakes and climate change: ophidism as a dynamic problem

Nori, J., Carrasco, P. A., & Leynaud, G. C. (2013) · Climatic Change · doi:10.1007/s10584-013-1019-6 · Cited by 75 · see citing works

A transcriptomic analysis of gene expression in the venom gland of the snake Bothrops alternatus (urutu)

Cardoso, K. C., da Silva, M. J., Costa, G. G., et al. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-605 · Cited by 74 · see citing works

Venomous Animals and their Venoms

(1971) · Elsevier eBooks · doi:10.1016/c2013-0-10436-9 · Cited by 73 · see citing works

Snake Venomic of Crotalus durissus terrificus—Correlation with Pharmacological Activities

Georgieva, D. N., Öhler, M., Seifert, J., von Bergen�, M., Arni, R. K., Genov, N. C., & Betzel, C. (2010) · Journal of Proteome Research · doi:10.1021/pr901042p · Cited by 72 · see citing works

Proteolytic, edematogenic and myotoxic activities of a hemorrhagic metalloproteinase isolated from Bothrops alternatus venom

Gay, C., Leiva, L. C., Maruñak, S. L., Teibler, P., & de Pérez, O. A. (2005) · Toxicon · doi:10.1016/j.toxicon.2005.06.019 · Cited by 69 · see citing works

Rattlesnake venoms, their actions and treatment

Tu, A. T. (1982) · Marcel Dekker eBooks · Cited by 67 · see citing works

Clinical and laboratory features of South American rattlesnake (Crotalus durissus terrificus) envenomation in children

Cupo, P., Azevedo-Marques, M. M., & Hering, S. E. (1988) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(88)90044-2 · Cited by 67 · see citing works

Revisão taxonômica do complexo Bothrops neuwiedi (Serpentes, Viperidae) com descrição de uma nova espécie

da Silva, V. X., & Rodrigues, M. T. (2008) · Phyllomedusa Journal of Herpetology · doi:10.11606/issn.2316-9079.v7i1p45-90 · Cited by 66 · see citing works

Isolation and characterization of a thrombin-like enzyme from the venom of Crotalus durissus terrificus.

Raw, I., Rocha, M., Esteves, M. I., et al. (1986) · PubMed · Cited by 66 · see citing works

Toxin synergism in snake venoms

Laustsen, A. H. (2016) · Toxin Reviews · doi:10.1080/15569543.2016.1220397 · Cited by 65 · see citing works

Cross-reactivity and heterologous neutralization of crotaline antivenoms used in Argentina

de Roodt, A. R., Dolab, J. A., Fernández, T., et al. (1998) · Toxicon · doi:10.1016/s0041-0101(97)00111-6 · Cited by 63 · see citing works

A Novel Phospholipase A2, BJ-PLA2, from the Venom of the Snake Bothrops jararaca: Purification, Primary Structure Analysis, and Its Characterization as a Platelet-Aggregation-Inhibiting Factor

Serrano, S. M. T., Reichl, A. P., Mentele, R., et al. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1230 · Cited by 63 · see citing works

Poor Regenerative Outcome after Skeletal Muscle Necrosis Induced by Bothrops asper Venom: Alterations in Microvasculature and Nerves

Hernández, R., Cabalceta, C., Saravia‐Otten, P., Chaves, A., Gutiérrez, J. M., & Rucavado, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019834 · Cited by 60 · see citing works

BaG, a new dimeric metalloproteinase/disintegrin from the Bothrops alternatus snake venom that interacts with α5β1 integrin

Cominetti, M. R., Ribeiro, J. U., Fox, J. W., & Selistre-de-Araújo, H. S. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(03)00298-4 · Cited by 59 · see citing works

Systemic skeletal muscle necrosis induced by crotoxin

Salvini, T. F., Amaral, A. C., Miyabara, E. H., et al. (2001) · Toxicon · doi:10.1016/s0041-0101(00)00245-2 · Cited by 58 · see citing works

Efectos proteolitico, hemorragico y mionecrotico de los venenos de serpientes costarricenses de los generos Bothrops, Crotalus y Lachesis

Gutiérrez, J. M., & Chaves, F. (1980) · Toxicon · doi:10.1016/0041-0101(80)90011-2 · Cited by 57 · see citing works

Isolation and functional characterization of a new acidic PLA2 Ba SpII RP4 of the Bothrops alternatus snake venom from Argentina

Denegri, M. E. G., Acosta, O., Huancahuire‐Vega, S., Martins‐de‐Souza, D., Marangoni, S., Maruñak, S. L., Teibler, P., Leiva, L. C., & Ponce-Soto, L. A. (2010) · Toxicon · doi:10.1016/j.toxicon.2010.02.031 · Cited by 56 · see citing works

The active components of crotoxin

Horst, J., Hendon, R. A., & Fraenkel‐Conrat, H. (1972) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(72)80077-9 · Cited by 56 · see citing works

Synergism between baltergin metalloproteinase and Ba SPII RP4 PLA2 from Bothrops alternatus venom on skeletal muscle (C2C12) cells

Bustillo, S., Gay, C., Denegri, M. E. G., Ponce-Soto, L. A., Joffé, E. B. D. K., Acosta, O., & Leiva, L. C. (2011) · Toxicon · doi:10.1016/j.toxicon.2011.11.007 · Cited by 55 · see citing works

Structural and functional properties of BaTX, a new Lys49 phospholipase A2 homologue isolated from the venom of the snake Bothrops alternatus

Ponce-Soto, L. A., Lomonte, B., Gutiérrez, J. M., et al. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.11.015 · Cited by 53 · see citing works

Rattlesnake Venoms: Their Actions and Treatment

STJERNHOLM, R. L. (1983) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1983.32.200 · Cited by 53 · see citing works

Purification and partial characterization of a thrombin-like enzyme, balterobin, from the venom of Bothrops alternatus

Smolka, M. B., Marangoni, S., Oliveira, B., et al. (1998) · Toxicon · doi:10.1016/s0041-0101(98)80008-1 · Cited by 50 · see citing works

[Regeneration and myogenesis of striated muscle].

Plaghki, L. (1985) · PubMed · Cited by 49 · see citing works

Bhalternin: Functional and structural characterization of a new thrombin-like enzyme from Bothrops alternatus snake venom

Costa, J. D. O., Fonseca, K. C., Mamede, C. C. N., et al. (2010) · Toxicon · doi:10.1016/j.toxicon.2010.02.014 · Cited by 48 · see citing works

Caracterizacion de las actividades biologicas de los venenos ‘amarillo’ y ‘blanco’ de Crotalus durissus ruruima comparados con el veneno de Crotalus durissus terrificus. Poder neutralizante de los antivenenos frente a los venenos de Crotalus durissus ruruima

Dos‐Santos, M. C., Ferreira, L. C. L., da Silva, W. D., et al. (1993) · Toxicon · doi:10.1016/0041-0101(93)90211-z · Cited by 47 · see citing works

Individual venom profiling of Crotalus durissus terrificus specimens from a geographically limited region: Crotamine assessment and captivity evaluation on the biological activities

Lourenço, A., Creste, C. F. Z., de Barros, L. C., et al. (2013) · Toxicon · doi:10.1016/j.toxicon.2013.01.006 · Cited by 47 · see citing works

BE-I-PLA2, a novel acidic phospholipase A2 from Bothrops erythromelas venom: Isolation, cloning and characterization as potent anti-platelet and inductor of prostaglandin I2 release by endothelial cells

Modesto, J. C. D. A., Spencer, P. J., Fritzen, M., et al. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.04.032 · Cited by 46 · see citing works

Bothroalternin, a thrombin inhibitor from the venom of Bothrops alternatus

Castro, H. C., Dutra, D. L. S., Oliveira-Carvalho, A. L., et al. (1998) · Toxicon · doi:10.1016/s0041-0101(98)00111-1 · Cited by 45 · see citing works

Phospholipase A2 enhances the endothelial cell detachment effect of a snake venom metalloproteinase in the absence of catalysis

Bustillo, S., Denegri, M. E. G., Gay, C., de Velde, A. C. V., Acosta, O., Angulo, Y., Lomonte, B., Gutiérrez, J. M., & Leiva, L. C. (2015) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2015.08.002 · Cited by 44 · see citing works

A bright future for integrative venomics

Calvete, J. J., & Lomonte, B. (2015) · Toxicon · doi:10.1016/j.toxicon.2015.10.024 · Cited by 43 · see citing works

Purification and Characterization of a Phosphodiesterase from Bothrops alternatus Snake Venom

Valério, A. A., Corradini, A. C., Panunto, P. C., et al. (2002) · Journal of Protein Chemistry · doi:10.1023/a:1022414503995 · Cited by 42 · see citing works

Degenerative and regenerative changes in murine skeletal muscle after injection of venom from the snake Bothrops asper: a histochemical and immunocytochemical study.

Arce, V., Brenes, F., & Gutiérrez, J. M. (1991) · Americanae (AECID Library) · Cited by 42 · see citing works

A new phospholipase a2 isoform isolated from Bothrops neuwiedii (yarará chica) venom with novel kinetic and chromatographic properties

Daniele, J. J., Bianco, I. D., Delgado, C., et al. (1997) · Toxicon · doi:10.1016/s0041-0101(97)00023-8 · Cited by 42 · see citing works

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina

Gay, C., Sanz, L., Calvete, J. J., et al. (2015) · Toxins · doi:10.3390/toxins8010009 · Cited by 42 · see citing works

Systemic alterations induced by a Bothrops alternatus hemorrhagic metalloproteinase (baltergin) in mice

Gay, C., Maruñak, S. L., Teibler, P., et al. (2008) · Toxicon · doi:10.1016/j.toxicon.2008.10.010 · Cited by 40 · see citing works

Gyroxin fails to modify in vitro release of labelled dopamine and acetylcholine from rat and mouse striatal tissue

Camillo, M. A. P., Paes, P. C. A., Troncone, L. R. P., & Rogero, J. R. (2001) · Toxicon · doi:10.1016/s0041-0101(00)00222-1 · Cited by 37 · see citing works

Evaluation of pro-inflammatory events induced by Bothrops alternatus snake venom

Echeverría, S., Leiguez, E., Guijas, C., Nascimento, N. G., Acosta, O., Teixeira, C., Leiva, L. C., & Rodríguez, J. P. (2017) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2017.12.022 · Cited by 37 · see citing works

Phosphodiesterase from Daboia russelli russelli venom: Purification, partial characterization and inhibition of platelet aggregation

Mitra, J., & Bhattacharyya, D. (2014) · Toxicon · doi:10.1016/j.toxicon.2014.06.004 · Cited by 34 · see citing works

Toxins as tools in the study of sodium channel distribution in the muscle fibre membrane

Brazil, O. V., & Fontana, M. D. (1993) · Toxicon · doi:10.1016/0041-0101(93)90124-2 · Cited by 34 · see citing works

South American rattlesnake bite in a Brazilian teaching hospital. Clinical and epidemiological study of 87 cases, with analysis of factors predictive of renal failure

Silveira, P. V. P., & Nishioka, S. D. A. (1992) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(92)90114-r · Cited by 34 · see citing works

Quantification of crotamine, a small basic myotoxin, in South American rattlesnake (Crotalus durissus terrificus) venom by enzyme-linked immunosorbent assay with parallel-lines analysis

Oguiura, N., Meléndez-Camargo, M. E., da Silva, A. R. P., et al. (2000) · Toxicon · doi:10.1016/s0041-0101(99)00157-9 · Cited by 33 · see citing works

Hematological, hemostatic and clinical chemistry disturbances induced by Crotalus durissus terrificus snake venom in dogs

Sousa-e-Silva, M. C. C., Tomy, S. C., Tavares, F. L., et al. (2003) · Human & Experimental Toxicology · doi:10.1191/0960327103ht392oa · Cited by 33 · see citing works

Kinetic and Pharmacological Characterization of Phospholipases A2 from Bothrops neuwiedii Venom

Daniele, J. J., Bianco, I. D., & Fidelio, G. D. (1995) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1995.1205 · Cited by 32 · see citing works

Estudo histopatológico das lesões causadas pelo veneno de urutu (Bothrops alternatus) em músculo esquelético de camundongos

Queiroz, L. S., & Petta, C. A. (1984) · Revista do Instituto de Medicina Tropical de São Paulo · doi:10.1590/s0036-46651984000500004 · Cited by 30 · see citing works

A study on the venom of Bothrops alternatus Duméril, Bibron and Duméril, from different regions of Argentina

Lanari, L. C., Rosset, S. D., González, M. E., et al. (2010) · Toxicon · doi:10.1016/j.toxicon.2010.01.015 · Cited by 29 · see citing works

Afibrinogenemia Following Snake Bite (Crotalus Durissus Terrificus)

Amaral, C. F. S., da Silva, O. A., López, M., et al. (1980) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1980.29.1453 · Cited by 28 · see citing works

Action of two phospholipases A2 purified from Bothrops alternatus snake venom on macrophages

Setúbal, S. D. S., Pontes, A. S., Furtado, J., Xavier, C. V., Silva, F. L., Kayano, A. M., Izidoro, L. F. M., Soares, A. M., Calderón, L. A., Stábeli, R. G., et al. (2013) · Biochemistry (Moscow) · doi:10.1134/s0006297913020089 · Cited by 28 · see citing works

Cytotoxicity and morphological analysis of cell death induced by Bothrops venoms from the northeast of Argentina

Bustillo, S., Lucero, H., Leiva, L., et al. (2009) · ˜The œJournal of venomous animals and toxins including tropical diseases · doi:10.1590/s1678-91992009000100004 · Cited by 28 · see citing works

South American snake venom proteins antigenically related to Bothrops asper myotoxins.

Lomonte, B., Mf, F., Me, R., et al. (1990) · PubMed · Cited by 27 · see citing works

Neutralization of Bothrops alternatus regional venom pools and individual venoms by antivenom: A systematic comparison

de Roodt, A. R., Lanari, L. C., de Oliveira, V. C., et al. (2011) · Toxicon · doi:10.1016/j.toxicon.2011.04.013 · Cited by 26 · see citing works

Actividades hemorrágica y edematizante y alteraciones histológicas en almohadilla plantar del ratón inducidas por venenos de serpientes de los géneros Bothrops y Crotalus de Argentina

de Pérez, O. C. A., Koscinczuk, P., Teibler, P., et al. (1998) · Toxicon · doi:10.1016/s0041-0101(98)00007-5 · Cited by 25 · see citing works

The role of complex formation in the neurotoxicity of crotoxin components A and B

Hendon, R. A., & Fraenkel‐Conrat, H. (1976) · Toxicon · doi:10.1016/0041-0101(76)90024-6 · Cited by 24 · see citing works

Regeneration and change of muscle fiber types after injury induced by a hemorrhagic fraction isolated from Agkistrodon contortrix laticinctus venom

Salvini, T. F., Belluzzo, S. S., Selistre-de-Araújo, H. S., et al. (2001) · Toxicon · doi:10.1016/s0041-0101(00)00188-4 · Cited by 23 · see citing works

New immunization protocol to produce crotalic antivenom combining Crotalus durissus terrificus venom and its PLA2

Fusco, L., Rodríguez, J. P., Teibler, P., et al. (2014) · Biologicals · doi:10.1016/j.biologicals.2014.09.001 · Cited by 23 · see citing works

Characterization of a basic phospholipase A2-homologue myotoxin isolated from the venom of the snake Bothrops neuwiedii (yarará chica) from Argentina

Geoghegan, P. A., Angulo, Y., Cangelosi, A., et al. (1999) · Toxicon · doi:10.1016/s0041-0101(99)00115-4 · Cited by 23 · see citing works

Accessibility of the active site of crotoxin B in the crotoxin complex

Canziani, G., Seki, C., & Vidal, J. C. (1982) · Toxicon · doi:10.1016/0041-0101(82)90068-x · Cited by 22 · see citing works

Rapid purification of serine proteinases from Bothrops alternatus and Bothrops moojeni venoms

de Oliveira, L. M. F., Ullah, A., Masood, R., et al. (2013) · Toxicon · doi:10.1016/j.toxicon.2013.10.016 · Cited by 22 · see citing works

SAXS study of the snake toxin ?-crotamine

Beltran, J. R., Mascarenhas, Y. P., Craievich, A. F., et al. (1990) · European Biophysics Journal · doi:10.1007/bf00258381 · Cited by 21 · see citing works

Rabbit IgG antibodies against phospholipase A2 from Crotalus durissus terrificus neutralize the lethal activity of the venom.

Rodríguez, J. P., Marzi, M. C. D., Maruñak, S. L., et al. (2006) · PubMed · Cited by 21 · see citing works

The Bothrops legacy: Vasoactive peptides from Brazil

Luft, F. C. (2008) · Journal of the Renin-Angiotensin-Aldosterone System · doi:10.3317/jraas.2008.009 · Cited by 19 · see citing works

Toxicity of Bothrops neuwiedi complex (“yarará chica”) venom from different regions of Argentina (Serpentes, Viperidae)

de Oliveira, V. C., Lanari, L. C., Hajos, S. E., et al. (2011) · Toxicon · doi:10.1016/j.toxicon.2011.01.012 · Cited by 19 · see citing works

Neurotoxicological effects of a thrombin-like enzyme isolated from Crotalus durissus terrificus venom (preliminary study)

de Torrent, R. M. R., Bongiovanni, B., Leiva, L. C., et al. (2007) · Toxicon · doi:10.1016/j.toxicon.2007.03.009 · Cited by 18 · see citing works

Purification and functional characterization of two fibrinogenolytic enzymes from Bothrops alternatus venom

Costa, J. D. O., Petric, C. B., Hamaguchi, A., et al. (2007) · ˜The œJournal of venomous animals and toxins including tropical diseases · doi:10.1590/s1678-91992007000300007 · Cited by 15 · see citing works

Serpientes Venenosas de Santa Fe, Argentina: Conocimientos sobre su Historia Natural Aplicados para la Prevención de Ofidismo

Giraudo, A. R., Arzamendia, V., López, S., et al. (2008) · FABICIB · doi:10.14409/fabicib.v12i1.819 · Cited by 14 · see citing works

Purification of a fragment obtained by autolysis of a PIIIb-SVMP from Bothrops alternatus venom

de Velde, A. C. V., Gay, C. C., Moritz, M. N. D. O., et al. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.02.063 · Cited by 14 · see citing works

Cloning and functional expression of secreted phospholipases A2 from Bothrops diporus (Yarará Chica)

Quartino, P. J. Y., Barra, J. L., & Fidelio, G. D. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.09.051 · Cited by 13 · see citing works

Cross-neutralization of the coagulant activity of Crotalus durissus terrificus venom from the northeast of Argentina by bivalent bothropic antivenom

Rodríguez, J. P., Gay, C., Fusco, L., et al. (2012) · ˜The œJournal of venomous animals and toxins including tropical diseases · doi:10.1590/s1678-91992012000100015 · Cited by 13 · see citing works

Local and systemic effects of BdipTX-I, a Lys-49 phospholipase A2 isolated from Bothrops diporus snake venom

Teixeira, L. F., de Carvalho, L. H., de Castro, O. B., Bastos, J. S. F., Néry, N. M., de Oliveira, G. A., Kayano, A. M., Soares, A. M., & Zuliani, J. P. (2017) · Toxicon · doi:10.1016/j.toxicon.2017.11.007 · Cited by 13 · see citing works

P9a(Cdt-PLA2) from Crotalus durissus terrificus as good immunogen to be employed in the production of crotalic anti-PLA2 IgG

Fusco, L., Rodríguez, J. P., Torres-Huaco, F. D., et al. (2015) · Toxicology Letters · doi:10.1016/j.toxlet.2015.06.528 · Cited by 11 · see citing works

Effect of monospecific antibodies against baltergin in myotoxicity induced by Bothrops alternatus venom from northeast of Argentina. Role of metalloproteinases in muscle damage

Gay, C., Maruñak, S. L., Teibler, P., et al. (2012) · Toxicon · doi:10.1016/j.toxicon.2012.11.028 · Cited by 11 · see citing works

Efficient muscle regeneration after highly haemorrhagic Bothrops alternatus venom injection

Denegri, M. E. G., Teibler, P., Maruñak, S. L., et al. (2016) · Toxicon · doi:10.1016/j.toxicon.2016.10.005 · Cited by 11 · see citing works

IgG antibodies against phospholipase A2 from Crotalus durissus terrificus: cross-reaction with venoms from Bothrops species from Argentina

Rodríguez, J. P., Marzi, M. D., Maruñak, S. L., et al. (2009) · ˜The œJournal of venomous animals and toxins including tropical diseases · doi:10.1590/s1678-91992009000300008 · Cited by 10 · see citing works

Histological and Ultrastructural Analyses of Muscle Damage Induced by a Myotoxin Isolated from Bothrops alternatus Snake Venom

Mamede, C. C. N., de Queiroz, M. R., Fonseca, K. C., et al. (2012) · Protein and Peptide Letters · doi:10.2174/092986613804725352 · Cited by 9 · see citing works

Neutralisation of the pharmacological activities of Bothrops alternatus venom by anti-PLA2 IgGs

Denegri, M. E. G., Maruñak, S. L., Todaro, J. S., et al. (2014) · Toxicon · doi:10.1016/j.toxicon.2014.05.016 · Cited by 7 · see citing works

Crystallization and high-resolution X-ray diffraction data collection of an Asp49 PLA2 from Bothrops jararacussu venom both in the presence and absence of Ca2+ ions

Murakami, M. T., Michelan‐Duarte, S., Cintra, A. C. O., et al. (2004) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2004.08.008 · Cited by 5 · see citing works

Acción del veneno de Bothrops diporus (yarará chica) del nordeste argentino sobre la hemostasia en diferentes mamíferos

Maruñak, S. L., Nuñez, S., Fernandez, C., et al. (2010) · Revista Veterinaria · doi:10.30972/vet.2111849 · Cited by 5 · see citing works

[Effects of Bothrops alternatus venom of Argentina on muscle and different organs in mices].

de Pérez, O. A., Koscinczuk, P., Negrette, M. S., et al. (1996) · PubMed · Cited by 4 · see citing works

Actividades farmacológicas de la fosfolipasa A2 Ba SpII RP4 del veneno de Bothrops alternatus

Denegri, M. E. G., Bustillo, S., Romero-Vargas, F. F., et al. (2012) · Revista Veterinaria · doi:10.30972/vet.2311801 · Cited by 2 · see citing works

Cambios microscópicos en ganglios linfáticos de ratones inoculados con veneno de Bothrops alternatus

Echeverría, S., Teibler, P., Maruñak, S. L., et al. (2016) · Revista Veterinaria · doi:10.30972/vet.262219 · Cited by 2 · see citing works

Pharmacological activities of Ba SpII RP4 PLA2 from Bothrops alternatus snake venom.

Denegri, M. E. G., Bustillo, S., Romero-Vargas, F. F., et al. (2012) · Revista Veterinaria · Cited by 1 · see citing works

Histological changes in lymphatic nodes of mice inoculated with venom of Bothrops alternatus.

Echeverría, S., Teibler, P., Maruñak, S. L., et al. (2015) · Revista Veterinaria · Cited by 1 · see citing works

QSAR without borders

Muratov, E. N., Bajorath, J., Sheridan, R. P., Tetko, I. V., Filimonov, D., Poroikov, V., Oprea, T. I., Baskin, I. I., Varnek, A., Roitberg, A., et al. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00098a · Cited by 913 · see citing works

Southern Pacific Rattlesnake bite: A unique clinical challenge

Wasserberger, J., Ordog, G. J., & Merkin, T. E. (2006) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2005.09.018 · Cited by 16 · see citing works

Snake venom hemorrhagins: Neutralization by commercial antivenoms

Mebs, D., Pohlmann, S., & Tenspolde, W. V. (1988) · Toxicon · doi:10.1016/0041-0101(88)90184-5 · Cited by 33 · see citing works

Acute phase reactions in patients bitten by Bothrops and Crotalus snakes

Barraviera, B. (1993) · Toxicon · doi:10.1016/0041-0101(93)90244-d · Cited by 2 · see citing works

Estimation of neurotoxic and myotoxic activities of snake venoms using a simple in vitro assay

Harvey, A. L., & Thomson, E. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)92343-h

Acute-phase reactions, including cytokines, in patients bitten by Bothrops and Crotalus snakes in Brazil

Barraviera, B., Lomonte, B., Tarkowski, A., et al. (1996) · Toxicon · doi:10.1016/s0041-0101(96)90018-5 · Cited by 4 · see citing works