Do Social Isolation and Loneliness Kill People with Alzheimer's Disease?
Open accessAbstract
Patients with AD have shortened life expectancy than the general older population is well established. Loneliness may be another risk factor to consider if we wish to understand and improve the premature mortality of AD.
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Several studies have shown an association of SDoH factors such as education level, isolation, and loneliness with the onset of Alzheimer's disease and related dementias (ADRD) in older adults.
“Several studies have shown the association of SDoH factors such as education level, isolation, and loneliness with the onset of Alzheimer’s disease and related dementias (ADRD) in older adults84–86.”
From Social determinants of health extraction from clinical notes across institutions using large language models (2025) · cites this paper as [86]
In “Do Social Isolation and Loneliness Kill People with Alzheimer's Disease?” (page unavailable), the paper describes social isolation as a risk factor for developing AD and reports an association between loneliness and incident mild cognitive impairment in older adults. It does not address education level, and its loneliness finding concerns MCI rather than the onset of AD or dementia. (LLM, conf=0.86)
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Cites
Survival in dementia and predictors of mortality: a review
Todd, S., Barr, S., Roberts, M., & Passmore, A. P. (2013) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.3946 · Cited by 417 · see citing works
Holwerda, T. J., van Tilburg, T. G., Deeg, D. J. H., Schutter, N., Van, R., Dekker, J., Stek, M. L., Beekman, A. T. F., & Schoevers, R. A. (2016) · British Journal of Psychiatry · doi:10.1192/bjp.bp.115.168005 · Cited by 153 · see citing works
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Research works printed but not linked: 11
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- Hinton WL, Levkoff S. Constructing Alzheimer's: narratives of lost identities, confusion and loneliness in old age. Cult Med Psychiatry. 1999; 23: 453-475. Enjoy OBM Geriatrics by: 1. Submitting a manuscript 2. Joining in volunteer reviewer bank 3. Joining Editorial Board 4. Guest editing a special issue For more details, please visit: http://www.lidsen.com/journals/geriatrics OBM Geriatrics
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Keloth, V. K., Selek, S., Chen, Q., Gilman, C., Fu, S., Dang, Y., Chen, X., Hu, X., Zhou, Y., He, H., et al. (2025) · npj Digital Medicine · doi:10.1038/s41746-025-01645-8 · Cited by 24 · see citing works
- Authors
- Barak, Y., & Glue, P.
- Affiliations
- University of Otago (NZ)
- Corresponding author
- Barak, Yoram
- Venue
- OBM Geriatrics
- Publisher
- LIDSEN Publishing Inc
- Published
- 2018-11-26
- Volume
- 02
- Issue
- 04
- Pages
- 1-5
- ISSN
- 2638-1311 (ISSN-L)
- OpenAlex
- W2902065466
- Cited by
- 4
- References
- 2
- Citations by year
- 2025: 2 · 2024: 1 · 2020: 1
- FWCI
- 0.20
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- OBM Geriatrics (publishedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- Alzheimer's disease, social isolation, loneliness, premature mortality, life expectancy, risk factors
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