Cited by 176Diet and metabolism studiesDiabetes Management and ResearchDietary Effects on Health

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A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes

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McKenzie, Amy L, Hallberg, Sarah J, Creighton, Brent C, Volk, Brittanie M, Link, Theresa M, Abner, Marcy K, Glon, Roberta M, McCarter, James P, Volek, Jeff S, Phinney, Stephen D·2017·JMIR Diabetes

DOI 10.2196/diabetes.6981PMC PMC6238887

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Abstract

BACKGROUND: Type 2 diabetes (T2D) is typically managed with a reduced fat diet plus glucose-lowering medications, the latter often promoting weight gain. OBJECTIVE: We evaluated whether individuals with T2D could be taught by either on-site group or remote means to sustain adequate carbohydrate restriction to achieve nutritional ketosis as part of a comprehensive intervention, thereby improving glycemic control, decreasing medication use, and allowing clinically relevant weight loss. METHODS: ) and related biomarkers of T2D were evaluated at baseline and 10-week follow-up. RESULTS: =1.503, P=.22). CONCLUSIONS: These initial results indicate that an individualized program delivered and supported remotely that incorporates nutritional ketosis can be highly effective in improving glycemic control and weight loss in adults with T2D while significantly decreasing medication use.

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Authors: McKenzie, A. L., Hallberg, S. J., Creighton, B. C., Volk, B. M., Link, T. M., Abner, M. K., Glon, R. M., McCarter, J. P., Volek, J. S., & Phinney, S. D.
Affiliations: Indiana University Health (US)
Corresponding author: Phinney, Stephen D
ORCID: McKenzie, Amy L
Hallberg, Sarah J
Creighton, Brent C
Volk, Brittanie M
Link, Theresa M
Abner, Marcy K
Glon, Roberta M
McCarter, James P
Volek, Jeff S
Phinney, Stephen D
Venue: JMIR Diabetes
Publisher: JMIR Publications Inc.
Published: 2017-03-07
Volume: 2
Issue: 1
Pages: e5
ISSN: 2371-4379 (ISSN-L)
DOI: 10.2196/diabetes.6981
PMC: PMC6238887
OpenAlex: W2593555386
Cited by: 176
References: 42
Citations by year: 2026: 6 · 2025: 9 · 2024: 33 · 2023: 14 · 2022: 23 · 2021: 25 · 2020: 23 · 2019: 19 · 2018: 19 · 2017: 5
FWCI: 13.36
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
Locations: JMIR Diabetes (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Keywords: type 2 diabetes, nutritional ketosis, carbohydrate restriction, glycemic control, HbA1c, weight loss, medication reduction, remote intervention, group intervention, diabetes self-management

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A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes

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