The DOI matches its Crossref record; 93 of the 93 references it cites were found in a registry or an index.
Regulation of Potassium Homeostasis
Open accessAbstract
Potassium is the most abundant cation in the intracellular fluid, and maintaining the proper distribution of potassium across the cell membrane is critical for normal cell function. Long-term maintenance of potassium homeostasis is achieved by alterations in renal excretion of potassium in response to variations in intake. Understanding the mechanism and regulatory influences governing the internal distribution and renal clearance of potassium under normal circumstances can provide a framework for approaching disorders of potassium commonly encountered in clinical practice. This paper reviews key aspects of the normal regulation of potassium metabolism and is designed to serve as a readily accessible review for the well informed clinician as well as a resource for teaching trainees and medical students.
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“An increase in ALD concentration leads to a modest increase in Na+-K+-ATPase abundance, which increases K+ flux into cells [30–32].”
From A mathematical model of potassium homeostasis: Effect of feedforward and feedback controls (2022) · cites this paper as [31]
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Citations
Cites
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
Nauli, S. M., Alenghat, F. J., Luo, Y., Williams, E., Vassilev, P., Li, X., Elia, A. E. H., Lu, W., Brown, E. M., Quinn, S. J., et al. (2003) · Nature Genetics · doi:10.1038/ng1076 · Cited by 2,057
Appel, L. J., Brands, M. W., Daniels, S. R., Karanja, N., Elmer, P. J., & Sacks, F. M. (2006) · Hypertension · doi:10.1161/01.hyp.0000202568.01167.b6 · Cited by 1,304
Lalioti, M. D., Zhang, J., Volkman, H. M., Kahle, K. T., Hoffmann, K. E., Toka, H. R., Nelson-Williams, C. J., Ellison, D. H., Flavell, R. A., Booth, C. J., et al. (2006) · Nature Genetics · doi:10.1038/ng1877 · Cited by 368
Sørensen, M. V., Großmann, S., Roesinger, M., Gresko, N., Todkar, A., Barmettler, G., Ziegler, U., Odermatt, A., Loffing‐Cueni, D., & Loffing, J. (2013) · Kidney International · doi:10.1038/ki.2013.14 · Cited by 360
Molecular diversity and regulation of renal potassium channels.
Hebert, S., Desir, G., Giebisch, G., & Wang, W.-H. (2005) · Physiological Reviews · doi:10.1152/physrev.00051.2003 · Cited by 323
Yang, S., Morimoto, T., Rai, T., Chiga, M., Sohara, E., Ohno, M., Uchida, K., Lin, S., Moriguchi, T., Shibuyà, H., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.03.009 · Cited by 315
Molecular clock is involved in predictive circadian adjustment of renal function
Zuber, A. M., Centeno, G., Pradervand, S., Nikolaeva, S., Maquelin, L., Cardinaux, L., Bonny, O., & Firsov, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904890106 · Cited by 274
Muscle K+, Na+, and Cl− disturbances and Na+-K+ pump inactivation: implications for fatigue
McKenna, M. J., Bangsbo, J., & Renaud, J. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01037.2007 · Cited by 272
Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins
Yamauchi, K., Rai, T., Kobayashi, K., Sohara, E., Suzuki, T., Itoh, T., Suda, S., Hayama, A., Sasaki, S., & Uchida, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306924101 · Cited by 270
Activation of the renal Na + :Cl − cotransporter by angiotensin II is a WNK4-dependent process
Castañeda‐Bueno, M., Cervantes-Pérez, L. G., Vázquez, N. H., Uribe, N., Kantesaria, S., Morla, L., Bobadilla, N. A., Doucet, A., Alessi, D. R., & Gamba, G. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200947109 · Cited by 261
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Collins, A. J., Pitt, B., Reaven, N. L., Funk, S. E., McGaughey, K. J., Wilson, D. J., & Bushinsky, D. A. (2017) · American Journal of Nephrology · doi:10.1159/000479802 · Cited by 411
On the Metabolism of Exogenous Ketones in Humans
Stubbs, B. J., Cox, P. J., Evans, R. D., Santer, P., Miller, J. J. J. J., Harrison, O. K., Magor‐Elliott, S. R. M., Hiyama, S., Stirling, M. J., & Clarke, K. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00848 · Cited by 417
Hypokalemia: a clinical update
Kardalas, E., Paschou, S. Α., Anagnostis, P. G., Muscogiuri, G., Siasos, G., & Vryonidou, A. (2018) · Endocrine Connections · doi:10.1530/ec-18-0109 · Cited by 364
Plant-based diets to manage the risks and complications of chronic kidney disease
Carrero, J. J., González-Ortíz, A., Avesani, C. M., Bakker, S. J. L., Bellizzi, V., Chauveau, P., Clase, C. M., Cupisti, A., Espinosa-Cuevas, Á., Molina, P., et al. (2020) · Nature Reviews Nephrology · doi:10.1038/s41581-020-0297-2 · Cited by 340
Vaidya, A., Mulatero, P., Baudrand, R. F., & Adler, G. K. (2018) · Endocrine Reviews · doi:10.1210/er.2018-00139 · Cited by 314
Metadata
- Authors
- Palmer, B. F.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Palmer, Biff F.
- ORCID
- Palmer, Biff F.
- Venue
- Clinical Journal of the American Society of Nephrology
- Published
- 2015-06
- Volume
- 10
- Issue
- 6
- Pages
- 1050-1060
- ISSN
- 1555-9041 (ISSN-L)
- PMC
- PMC4455213
- OpenAlex
- W2147621031
- Cited by
- 535
- References
- 93
- Citations by year
- 2026: 51 · 2025: 40 · 2024: 59 · 2023: 65 · 2022: 63 · 2021: 46 · 2020: 57 · 2019: 47 · 2018: 36 · 2017: 42 · 2016: 20 · 2015: 8
- FWCI
- 4.05
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Journal of the American Society of Nephrology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Nephrology › Potassium and Related Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
- Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
- Keywords
- potassium homeostasis, potassium metabolism, renal potassium excretion, intracellular fluid, potassium disorders
- MeSH terms
- Aldosterone, Animals, Circadian Rhythm, Homeostasis, Humans, Hypertension, Kidney, Potassium, Renin-Angiotensin System, Renal Elimination
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