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Finasteride Metabolism and Pharmacogenetics: New Approaches to Personalized Prevention of Prostate Cancer
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“The uridine diphosphoglucuronosyl transferase (UGT) enzymes also participate in finasteride metabolism, but there is little literature to suggest which UGT protein(s) are involved in its glucuronidation [26].”
From Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride (2023) · cites this paper as [26]
In the citing paper
“Nonetheless, two studies identified associations between variants in different genes (i.e., CYP3A4, SRD5A2) with variations in finasteride serum concentrations [25] or drug’s affinity for its target [26].”
From Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride (2023) · cites this paper as [26]
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Brown, G., Albers, J. J., Fisher, L. D., Schaefer, S. M., Lin, J.-T., Kaplan, C., Zhao, X.-Q., Bisson, B. D., Fitzpatrick, V. F., & Dodge, H. T. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011083231901 · Cited by 2,159
Rare Variants Create Synthetic Genome-Wide Associations
Dickson, S. P., Wang, K., Krantz, I., Hakonarson, H., & Goldstein, D. B. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000294 · Cited by 857
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
Hofland, J., van Weerden, W. M., Dits, N. F. J., Steenbergen, J., van Leenders, G. J. L. H., Jenster, G., Schröder, F. H., & de Jong, F. H. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-2092 · Cited by 176
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Cited by
Villapalos-García, G., Zubiaur, P., Marián-Revilla, C., Soria-Chacartegui, P., Navares-Gómez, M., Mejía-Abril, G., Rodríguez-Lopez, A., González-Iglesias, E., Martín-Vílchez, S., Román, M., et al. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13111566 · Cited by 4
Metadata
- Authors
- Hulin-Curtis, S. L., Petit, D., Figg, W. D., Hsing, A. W., & Reichardt, J. K.
- Affiliations
- University of Sydney, Bosch Institute, Camperdown, New South Wales, Australia: School of Pharmacy & Molecular Sciences, James Cook University, Townsville, Queensland, Australia.
- Molecular Pharmacology Section, Medical Oncology Branch, National Cancer Institute, MD, USA
- Division of Cancer Epidemiology & Genetics, National Cancer Institute, MD, USA
- Venue
- Future Oncology
- Publisher
- Informa UK Limited
- Published
- 2010-12-13
- Volume
- 6
- Issue
- 12
- Pages
- 1897-1913
- ISSN
- 1479-6694
- 1744-8301
- Cited by
- 19
- References
- 3
- Language
- en
- Funders
- National Cancer Institute (PO1 CA108964)
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.