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Cited by 224

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Biocompatibility and Toxicity of Graphene Quantum Dots for Potential Application in Photodynamic Therapy

Open access
Tabish, Tanveer A, Scotton, Chris J, J Ferguson, Daniel C, Lin, Liangxu, der Veen, Anienke van, Lowry, Sophie, Ali, Muhammad, Jabeen, Farhat, Ali, Muhammad, Winyard, Paul G, Zhang, Shaowei·2018·Nanomedicine

Abstract

AIM: Achieving reliably high production of reactive oxygen species (ROS) in photodynamic therapy (PDT) remains challenging. Graphene quantum dots (GQDs) hold great promise for PDT. However, the photochemical processes leading to GQD-derived ROS generation have not yet been fully elucidated. MATERIALS & METHODS: Physicochemical characteristics of GQDs were comprehensively investigated, including electron paramagnetic resonance analysis of singlet oxygen production. Dark toxicity was assessed in vitro and in vivo. RESULTS: GQDs demonstrated excellent photoluminescent features, corrosion resistance, high water solubility, high photo/pH-stability, in vitro and in vivo biocompatibility and very efficient singlet oxygen/ROS generation. CONCLUSION: The enhanced ROS generation, combined with good biocompatibility and minimal toxicity in vitro and in vivo support the potential of GQDs for future PDT application.

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Metadata

Authors
Tabish, T. A., Scotton, C. J., J Ferguson, D. C., Lin, L., der Veen, A. V., Lowry, S., Ali, M., Jabeen, F., Ali, M., Winyard, P. G., & Zhang, S.
Venue
Nanomedicine
Published
2018-08
Volume
13
Issue
15
Pages
1923-1937
ISSN
  • 1743-5889 (ISSN-L)
  • 1748-6963
OpenAlex
W2887909456
Cited by
224
References
3
FWCI
7.32
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Biocompatibility and Toxicity of Graphene Quantum Dots for Potential Application in Photodynamic Therapy. https://app.cochat.ai/papers/10.2217/nnm-2018-0018
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Tabish, T. A., Scotton, C. J., J Ferguson, D. C., Lin, L., der Veen, A. V., Lowry, S., Ali, M., Jabeen, F., Ali, M., Winyard, P. G., & Zhang, S. (2018). Biocompatibility and Toxicity of Graphene Quantum Dots for Potential Application in Photodynamic Therapy. Nanomedicine. https://doi.org/10.2217/nnm-2018-0018

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