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Cited by 328

The DOI matches its Crossref record.

Exact Significance Testing to Establish Treatment Equivalence with Ordered Categorical Data

Mehta, Cyrus R., Patel, Nitin R., Tsiatis, Anastasios A.·1984·Biometrics
DOI 10.2307/2530927
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Abstract

This communication concerns the problem of establishing the therapeutic equivalence of two treatments that are being compared on the basis of ordered categorical data. The problem is formulated as a significance test in which the null hypothesis specifies a treatment difference. An efficient numerical algorithm for computing the exact significance level is provided, along with a simple method for obtaining the asymptotic significance level. Both methods are applied to a clinical trial of a new agent versus an active control. Guidelines for when to use the exact procedure and when to rely on asymptotic theory are provided.

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Metadata

Authors
Mehta, C. R., Patel, N. R., & Tsiatis, A. A.
Venue
Biometrics
Publisher
JSTOR
Published
1984-09
Volume
40
Issue
3
Pages
819
ISSN
0006-341X (ISSN-L)
DOI
10.2307/2530927
OpenAlex
W2090653702
Cited by
328
References
0
FWCI
4.37
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Exact Significance Testing to Establish Treatment Equivalence with Ordered Categorical Data. https://app.cochat.ai/papers/10.2307/2530927
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Mehta, C. R., Patel, N. R., & Tsiatis, A. A. (1984). Exact Significance Testing to Establish Treatment Equivalence with Ordered Categorical Data. Biometrics. https://doi.org/10.2307/2530927

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.