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Cited by 733

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Random-Effects Models for Serial Observations with Binary Response

Stiratelli, Robert, Laird, Nan, Ware, James H.·1984·Biometrics

Abstract

This paper presents a general mixed model for the analysis of serial dichotomous responses provided by a panel of study participants. Each subject's serial responses are assumed to arise from a logistic model, but with regression coefficients that vary between subjects. The logistic regression parameters are assumed to be normally distributed in the population. Inference is based upon maximum likelihood estimation of fixed effects and variance components, and empirical Bayes estimation of random effects. Exact solutions are analytically and computationally infeasible, but an approximation based on the mode of the posterior distribution of the random parameters is proposed, and is implemented by means of the EM algorithm. This approximate method is compared with a simpler two-step method proposed by Korn and Whittemore (1979, Biometrics 35, 795-804), using data from a panel study of asthmatics originally described in that paper. One advantage of the estimation strategy described here is the ability to use all of the data, including that from subjects with insufficient data to permit fitting of a separate logistic regression model, as required by the Korn and Whittemore method. However, the new method is computationally intensive.

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Metadata

Authors
Stiratelli, R., Laird, N., & Ware, J. H.
Venue
Biometrics
Publisher
JSTOR
Published
1984-12
Volume
40
Issue
4
Pages
961
ISSN
0006-341X (ISSN-L)
OpenAlex
W2024085858
Cited by
733
References
16
FWCI
7.42
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Random-Effects Models for Serial Observations with Binary Response. https://app.cochat.ai/papers/10.2307/2531147
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Stiratelli, R., Laird, N., & Ware, J. H. (1984). Random-Effects Models for Serial Observations with Binary Response. Biometrics. https://doi.org/10.2307/2531147

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