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Analysis of Human Genetic Linkage.

Edwards, A. W. F., Ott, J.·1992·Biometrics

Abstract

The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book. New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to linkage and association analysis. A chapter on two-locus inheritance introduces the reader to many of the intricate aspects of complex traits. Although the book's primary audience is in the field of genetics, physicians and others without sophisticated training in genetics can understand and apply the principles and techniques discussed.

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Metadata

Authors
Edwards, A. W. F., & Ott, J.
Venue
Biometrics
Publisher
JSTOR
Published
1992-09
Volume
48
Issue
3
Pages
975
ISSN
0006-341X (ISSN-L)
OpenAlex
W2089221493
Cited by
1,691
References
0
FWCI
45.01
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Analysis of Human Genetic Linkage. https://app.cochat.ai/papers/10.2307/2532370
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Edwards, A. W. F., & Ott, J. (1992). Analysis of Human Genetic Linkage. Biometrics. https://doi.org/10.2307/2532370

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