Genetic Data Analysis II.
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The lack of information about haplotype phase weakens the signal of nonrandom association sufficiently that quantifying LD in genotypic data is not often taken.
“The extent of LD in genotypic data2,9 can be quantified, but the lack of information about the haplotype phase weakens the signal of nonrandom association sufficiently that this approach is not often taken.”
From Linkage disequilibrium--understanding the evolutionary past and mapping the medical future. (2008) · cites this paper as [2]
There is no agreement about which LD statistic is best or most useful, in part because different statistics are sensitive to different population genetic processes.
“There is no agreement about which is the best or most useful statistic2,33,34, in part because different statistics are sensitive to different population genetic processes that can cause nonrandom association.”
From Linkage disequilibrium--understanding the evolutionary past and mapping the medical future. (2008) · cites this paper as [2]
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Linkage disequilibrium--understanding the evolutionary past and mapping the medical future.
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Common deletions and SNPs are in linkage disequilibrium in the human genome
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Comparison of Genetic Distance Measures Using Human SNP Genotype Data
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- Authors
- Weir, B. S.
- Corresponding author
- Weir, B. S.
- ORCID
- Weir, B. S.
- Venue
- Biometrics
- Publisher
- JSTOR
- Published
- 1997-03
- Volume
- 53
- Issue
- 1
- Pages
- 392
- ISSN
- 0006-341X (ISSN-L)
- OpenAlex
- W2062026889
- Cited by
- 2,263
- References
- 0
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 14 · 2023: 23 · 2022: 50 · 2021: 34 · 2020: 26 · 2019: 37 · 2018: 26 · 2017: 41 · 2016: 46 · 2015: 57 · 2014: 92 · 2013: 108 · 2012: 113
- FWCI
- 38.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biometrics (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genetics, Bioinformatics, and Biomedical Research
- Keywords
- genetic data analysis, population genetics, linkage analysis
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