The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery
Abstract
We examine the relationship between firm size and research productivity in the pharmaceutical industry. Using detailed internal firm data, we find that larger research efforts are more productive, not only because they enjoy economies of scale, but also because they realize economies of scope by sustaining diverse portfolios of research projects that capture internal and external knowledge spillovers. In pharmaceuticals, economies of scope in research are important in shaping the boundaries of the firm, and it may be worth tolerating the static efficiency loss attributable to the market power of large firms in exchange for their superior innovative performance.
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Cites
Innovation and Learning: The Two Faces of R & D
Cohen, W. M., & Levinthal, D. A. (1989) · The Economic Journal · doi:10.2307/2233763 · Cited by 7,530
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Hay, M., Thomas, D. W., Craighead, J. L., Economides, C., & Rosenthal, J. (2014) · Nature Biotechnology · doi:10.1038/nbt.2786 · Cited by 2,536
Dahlander, L., & Gann, D. M. (2010) · Research Policy · doi:10.1016/j.respol.2010.01.013 · Cited by 2,435
Innovation objectives, knowledge sources, and the benefits of breadth
Leiponen, A., & Helfat, C. E. (2010) · Strategic Management Journal · doi:10.1002/smj.807 · Cited by 1,341
The Burden of Knowledge and the “Death of the Renaissance Man”: Is Innovation Getting Harder?
JONES, B. F. (2009) · Review of Economic Studies · doi:10.1111/j.1467-937x.2008.00531.x · Cited by 1,058
The productivity crisis in pharmaceutical R&D
Pammolli, F., Magazzini, L., & Riccaboni, M. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3405 · Cited by 918
The Emergence of Organizations and Markets
Padgett, J. F., & Powell, W. W. (2012) · doi:10.23943/princeton/9780691148670.001.0001 · Cited by 745
Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules
Azoulay, P., Graff Zivin, J. S., Li, D., & Sampat, B. N. (2019) · The Review of Economic Studies · doi:10.1093/restud/rdy034 · Cited by 349
Metadata
- Authors
- Henderson, R., & Cockburn, I.
- Venue
- The RAND Journal of Economics
- Publisher
- Wiley
- Published
- 1996
- Volume
- 27
- Issue
- 1
- Pages
- 32
- ISSN
- 0741-6261 (ISSN-L)
- OpenAlex
- W3123271837
- Cited by
- 1,388
- References
- 1
- FWCI
- 38.25
- Type
- journal article
- Language
- en
- Open access
- closed
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
