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Huntington's Disease
Abstract
ted by both sexes. Each child of an afflicted parent has a 50 percent chance of inheriting the disease. This risk continues uninterrupted from one generation to the next. Occasionally, a parent dies before the age when the symptoms characteristically appear, and this may give the impression, incorrectly, that Huntington's disease has skipped a generation(2). The age of onset of symptoms is extraordinarily inconsistent. Although most individuals first develop symptoms between the ages of 30 and 40 years, symptoms can occur between 20 and 60, a span of four decades. Rare cases have been
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Citations
Cited by
MACDONALD, M. (1993) · Cell · doi:10.1016/0092-8674(93)90585-e · Cited by 8,366
The roles of intracellular protein-degradation pathways in neurodegeneration
Rubinsztein, D. C. (2006) · Nature · doi:10.1038/nature05291 · Cited by 1,625
Tabrizi, S. J., Langbehn, D. R., Leavitt, B. R., Roos, R. A., Durr, A., Craufurd, D., Kennard, C., Hicks, S. L., Fox, N. C., Scahill, R. I., et al. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70170-x · Cited by 984
Nuclear and Neuropil Aggregates in Huntington’s Disease: Relationship to Neuropathology
Gutekunst, C.-A., Li, S.-H., Yi, H., Mulroy, J. S., Kuemmerle, S., Jones, R., Rye, D., Ferrante, R. J., Hersch, S. M., & Li, X.-J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02522.1999 · Cited by 914
Apoptosis and Caspases in Neurodegenerative Diseases
Friedlander, R. M. (2003) · New England Journal of Medicine · doi:10.1056/nejmra022366 · Cited by 873
Metadata
- Authors
- Stipe, J., White, D., & Arsdale, E. V.
- Venue
- The American Journal of Nursing
- Publisher
- JSTOR
- Published
- 1979-08
- Volume
- 79
- Issue
- 8
- Pages
- 1428
- ISSN
- 0002-936X (ISSN-L)
- OpenAlex
- W2769888961
- Cited by
- 602
- References
- 0
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- Stipe, J., White, D., & Arsdale, E. V. (1979). Huntington's Disease. The American Journal of Nursing. https://doi.org/10.2307/3424618
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
