The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Misunderstanding in Clinical Research: Distinguishing Therapeutic Misconception, Therapeutic Misestimation, & Therapeutic Optimism
Abstract
Sam Horng, Christine Grady, Misunderstanding in Clinical Research: Distinguishing Therapeutic Misconception, Therapeutic Misestimation, & Therapeutic Optimism, IRB: Ethics & Human Research, Vol. 25, No. 1 (Jan. - Feb., 2003), pp. 11-16
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“The consent of the prospective parents may also be compromised through a misunderstanding of the nature of the research, whether through ‘therapeutic misconception’ or ‘therapeutic misestimation’ (Horng and Grady 2003).”
From Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic (2023) · cites this paper as Horng and Grady 2003
Citations
Cites
What Makes Clinical Research Ethical?
Emanuel, E. J. (2000) · JAMA · doi:10.1001/jama.283.20.2701 · Cited by 2,710
A history and theory of informed consent
Kapp, M. B. (1986) · Journal of Legal Medicine · doi:10.1080/01947648609513478 · Cited by 2,331
False Hopes and Best Data: Consent to Research and the Therapeutic Misconception
Appelbaum, P. S., Roth, L. H., Lidz, C. W., Benson, P., & Winslade, W. (1987) · The Hastings Center Report · doi:10.2307/3562038 · Cited by 954
Quality of informed consent in cancer clinical trials: a cross-sectional survey
Joffe, S., Cook, E. F., Cleary, P. D., Clark, J. W., & Weeks, J. C. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06805-2 · Cited by 655
Communicating Statistical Information
Hoffrage, U., Lindsey, S., Hertwig, R., & Gigerenzer, G. (2000) · Science · doi:10.1126/science.290.5500.2261 · Cited by 651
Explaining risks: turning numerical data into meaningful pictures
Edwards, A., Elwyn, G., & Mulley, A. (2002) · BMJ · doi:10.1136/bmj.324.7341.827 · Cited by 644
Perceptions of cancer patients and their physicians involved in phase I trials.
Daugherty, C., Ratain, M. J., Grochowski, E., Stocking, C., Kodish, E., Mick, R., & Siegler, M. (1995) · Journal of Clinical Oncology · doi:10.1200/jco.1995.13.5.1062 · Cited by 515
Understanding patients' decisions. Cognitive and emotional perspectives
Redelmeier, D. A. (1993) · JAMA · doi:10.1001/jama.270.1.72 · Cited by 392
Defining and Describing Benefit Appropriately in Clinical Trials
King, N. M. P. (2000) · Journal of Law, Medicine & Ethics · doi:10.1111/j.1748-720x.2000.tb00685.x · Cited by 226
Professional Integrity in Clinical Research
Miller, F. G. (1998) · JAMA · doi:10.1001/jama.280.16.1449 · Cited by 201
Cited by
Clinical Trials and Medical Care: Defining the Therapeutic Misconception
Henderson, G. E., Churchill, L. R., Davis, A. M., Easter, M. M., Grady, C., Joffe, S., Kass, N., King, N. M. P., Lidz, C. W., Miller, F. G., et al. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040324 · Cited by 466
Self-citationHalpern, J., Paolo, D., & Huang, A. (2019) · Journal of Medical Ethics · doi:10.1136/medethics-2018-105226 · Cited by 34
Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic
Ranisch, R., Trettenbach, K., & Arnason, G. (2023) · Medicine, Health Care and Philosophy · doi:10.1007/s11019-022-10115-x · Cited by 19
How well informed is the informed consent for cancer clinical trials?
Malik, L., Kuo, J., Yip, D., & Mejia, A. (2014) · Clinical Trials · doi:10.1177/1740774514548734 · Cited by 18
Metadata
- Authors
- Horng, S., & Grady, C.
- Venue
- IRB: Ethics and Human Research
- Publisher
- Wiley
- Published
- 2003-01
- Volume
- 25
- Issue
- 1
- Pages
- 11
- ISSN
- 0193-7758
- Cited by
- 243
- References
- 15
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- CoChat. (2026). Citation check: Misunderstanding in Clinical Research: Distinguishing Therapeutic Misconception, Therapeutic Misestimation, & Therapeutic Optimism. https://app.cochat.ai/papers/10.2307/3564408
- The paper
- Horng, S., & Grady, C. (2003). Misunderstanding in Clinical Research: Distinguishing Therapeutic Misconception, Therapeutic Misestimation, & Therapeutic Optimism. IRB: Ethics and Human Research. https://doi.org/10.2307/3564408
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.