Cited by 91Tissue Engineering and Regenerative Medicinebiodegradable polymer synthesis and propertiesElectrospun Nanofibers in Biomedical Applications

Polymeric Materials for Tissue Engineering of Arterial Substitutes

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Ravi, Swathi, Qu, Zheng, Chaikof, Elliot L.·2009·Vascular

Abstract

Cardiovascular disease is the leading cause of mortality in the United States. The limited availability of healthy autologous vessels for bypass grafting procedures has led to the fabrication of prosthetic vascular conduits. Synthetic polymeric materials, while providing the appropriate mechanical strength, lack the compliance and biocompatibility that bioresorbable and naturally occurring protein polymers offer. Vascular tissue engineering approaches have emerged in order to meet the challenges of designing a vascular graft with long-term patency. In vitro culture techniques that have been explored with vascular cell seeding of polymeric scaffolds and the use of bioactive polymers for in situ arterial regeneration have yielded promising results. This review describes the development of polymeric materials in various tissue engineering strategies for the improvement in the mechanical and biological performance of an arterial substitute.

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  • Tubular PHB textiles are used to promote tissue healing in large vessels and hollow organs.

    “Tubular PHB textiles are also used to promote tissue healing in large vessels and hollow organs [97].”

    From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [97]

    The Degradable Polymers as Scaffolds section describes PGA/polyhydroxyoctanoate aortic grafts and a PGA/poly-4-hydroxybutyrate construct, not tubular PHB textiles. Searches for PHB textiles and hollow-organ applications found no passage addressing their claimed use; the relevant passages have no page numbers in our copy. (LLM, conf=0.75)

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Authors
Ravi, S., Qu, Z., & Chaikof, E. L.
Affiliations
Georgia Institute of Technology (US)
Corresponding author
Chaikof, Elliot L.
Venue
Vascular
Published
2009-06
Volume
17
Issue
1_suppl
Pages
45-54
ISSN
  • 1708-5381 (ISSN-L)
  • 1708-539X
OpenAlex
W2137267760
Cited by
91
References
1
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FWCI
1.77
Type
journal article
Language
en
Open access
Locations
  • Vascular (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Heart, Lung, and Blood Institute (R01HL060464, R01HL056819, R01HL083867, R01HL071136)
Topics
  • Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
Keywords
arterial substitutes, vascular grafts, polymer scaffolds, tissue engineering, bioresorbable polymers, protein polymers, graft patency, biocompatibility, mechanical properties, bypass grafting
MeSH terms
Animals, Biocompatible Materials, Biopolymers, Blood Vessel Prosthesis, Humans, Peripheral Vascular Diseases, Blood Vessel Prosthesis Implantation, Tissue Engineering, Endothelial Cells, Tissue Scaffolds

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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