Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential
Abstract
Nano- to micro-structured biodegradable poly(L-lactide-co-epsilon-caprolactone) (PLCL) fabrics were prepared by electrospinning. Electrospun microfiber fabrics with different compositions of PLCL (mol% in feed; 70/30, 50/50, and 30/70), poly(L-lactide) (PLL) and poly(epsilon-caprolactone) (PCL) were obtained using methylene chloride (MC) as a solvent. The PLL microfiber exhibited a nanoscale-pore structure with a pore diameter of approximately 200-800 nm at the surface and subsurface regions, whereas such a surface structure was hardly observed in other polymers containing CL. The microfiber fabric made of PLCL 50/50 was elastomeric. Nanoscale-fiber fabrics with PLCL 50/50 (approx. 0.3 or 1.2 microm in diameter) were electrospun using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as a solvent. Mercury porosimetry showed that the decrease in the fiber diameter of the fabric decreased porosity, but increased fiber density and mechanical strength. Human umbilical vein endothelial cells (HUVECs) were adhered well and proliferated on the small-diameter-fiber fabrics (0.3 and 1.2 microm in diameter), both of which are dense fabrics, whereas markedly reduced cell adhesion, restricted cell spreading and no signs of proliferation were observed on the large-diameter-fiber fabric (7.0 microm in diameter). The potential biomedical application of electrospun PLCL 50/50 was discussed.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
PLCL's adaptability through surface modification, blending with bioactive molecules, and processing through electrospinning, 3D printing, and supercritical carbon dioxide foaming has extended its use to multiple fields.
“In addition to its inherent properties, PLCL’s adaptability through surface modification, blending with bioactive molecules, and processing through advanced manufacturing techniques such as electrospinning, 3D printing, and supercritical carbon dioxide (scCO₂) foaming has extended its use to multiple fields [11–13].”
From Application of PLCL as a biodegradable polymer in biomedical engineering (2026) · cites this paper as [11]
Cites
Nanometre diameter fibres of polymer, produced by electrospinning
Reneker, D. H., & Chun, I. (1996) · Nanotechnology · doi:10.1088/0957-4484/7/3/009 · Cited by 3,534 · see citing works
Electrospun nanofibrous structure: A novel scaffold for tissue engineering
Li, W., Laurencin, C. T., Caterson, E. J., Tuan, R. S., & Ko, F. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.10167 · Cited by 2,429 · see citing works
Electrospinning of Collagen Nanofibers
Matthews, J. A., Wnek, G. E., Simpson, D. G., & Bowlin, G. L. (2002) · Biomacromolecules · doi:10.1021/bm015533u · Cited by 2,253 · see citing works
A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering
Yoshimoto, H., Shin, Y.-S., Terai, H., & Vacanti, J. P. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00635-x · Cited by 1,975 · see citing works
Note on a Method of Determining the Distribution of Pore Sizes in a Porous Material
Washburn, E. W. (1921) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.7.4.115 · Cited by 1,890 · see citing works
COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR
Elsdale, T., & Bard, J. (1972) · The Journal of Cell Biology · doi:10.1083/jcb.54.3.626 · Cited by 1,529 · see citing works
Nanostructured Fibers via Electrospinning
Bognitzki, M., Czado, W., Frese, T., Schaper, A., Hellwig, M., Steinhart, M., Greiner, A., & Wendorff, J. H. (2001) · Advanced Materials · doi:10.1002/1521-4095(200101)13:1 · Cited by 1,236 · see citing works
Experimental characterization of electrospinning: the electrically forced jet and instabilities
Shin, Y.-S., Hohman, M. M., Brenner, M. P., & Rutledge, G. C. (2001) · Polymer · doi:10.1016/s0032-3861(01)00540-7 · Cited by 1,069 · see citing works
Mo, X., Xu, C. Y., Kotaki, M., & Ramakrishna, S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2003.08.042 · Cited by 803 · see citing works
Biodegradable Polymer Scaffolds with Well-Defined Interconnected Spherical Pore Network
Ma, P. X., & Choi, J. (2001) · Tissue Engineering · doi:10.1089/107632701300003269 · Cited by 621 · see citing works
Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation
Mikos, A. G., Bao, Y., Griffith, L. G., Ingber, D. E., Vacanti, J. P., & Langer, R. (1993) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820270207 · Cited by 606 · see citing works
Kidoaki, S., Kwon, I. K., & Matsuda, T. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.01.063 · Cited by 548 · see citing works
Self-citationIn vitro reaction of endothelial cells to polymer demixed nanotopography
Dalby, M. J., Riehle, M. O., Johnstone, H., Affrossman, S., & Curtis, A. S. G. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00424-0 · Cited by 461 · see citing works
Polylactones: 31. Sn(II)octoate-initiated polymerization of L-lactide: a mechanistic study
Kricheldorf, H. R., Kreiser-Saunders, I., & Boettcher, C. (1995) · Polymer · doi:10.1016/0032-3861(95)93928-f · Cited by 411 · see citing works
Park, A., Wu, B. M., & Griffith, L. G. (1998) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856298x00451 · Cited by 322 · see citing works
Lee, K. H., Kim, H. Y., La, Y. M., Lee, D. R., & Sung, N. H. (2002) · Journal of Polymer Science Part B Polymer Physics · doi:10.1002/polb.10293 · Cited by 251 · see citing works
Nanofiber garlands of polycaprolactone by electrospinning
Reneker, D. H., Kataphinan, W., Theron, A., Zussman, E., & Yarin, A. L. (2002) · Polymer · doi:10.1016/s0032-3861(02)00595-5 · Cited by 240 · see citing works
den Braber, E. T., de Ruijter, J. E., Ginsel, L. A., von Recum, A. F., & Jansen, J. A. (1996) · Biomaterials · doi:10.1016/0142-9612(96)00032-4 · Cited by 208 · see citing works
Tissue engineering: the biophysical background
Curtis, A. S. G., & Riehle, M. O. (2001) · Physics in Medicine and Biology · doi:10.1088/0031-9155/46/4/201 · Cited by 199 · see citing works
Grijpma, D. W., Zondervan, G. J., & Pennings, A. J. (1991) · Polymer Bulletin · doi:10.1007/bf00316902 · Cited by 170 · see citing works
den Dunnen, W. F. A., van der Lei, B., Robinson, P. H., Holwerda, A., Pennings, A. J., & Schakenraad, J. M. (1995) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820290612 · Cited by 137 · see citing works
Microtopography and Soft Tissue Response
Campbell, C., & von Recum, A. F. (1989) · Journal of Investigative Surgery · doi:10.3109/08941938909016503 · Cited by 134 · see citing works
Pasch, H., & Rode, K. (1995) · Journal of Chromatography A · doi:10.1016/0021-9673(95)00061-q · Cited by 114 · see citing works
Meniscal tissue regeneration in porous 50/50 copoly(l-lactide/ε-caprolactone) implants
de Groot, J. H., Zijlstra, F. M., Kuipers, H. W., Pennings, A. J., Klompmaker, J., Veth, R. P. H., & Jansen, H. W. B. (1997) · Biomaterials · doi:10.1016/s0142-9612(96)00169-x · Cited by 109 · see citing works
Model of 1,1,1,3,3,3-Hexafluoro-propan-2-ol for Molecular Dynamics Simulations
Fioroni, M., Burger, K., Mark, A. E., & Roccatano, D. (2001) · The Journal of Physical Chemistry B · doi:10.1021/jp012476q · Cited by 79 · see citing works
Kwon, I. K., Park, K. D., Choi, S., Lee, S.-H., Lee, E. B., Na, J. S., Kim, S. H., & Kim, Y. H. (2001) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/15685620152691904 · Cited by 32 · see citing works
Hiljanen-Vainio, M., Karjalainen, T., & Sepp�l�, J. (1996) · Journal of Applied Polymer Science · doi:10.1002/(sici)1097-4628(19960222)59:8
Flagged first, then by citations
1 of the 28 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Electrospinning: A Fascinating Method for the Preparation of Ultrathin Fibers
Greiner, A., & Wendorff, J. H. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200604646 · Cited by 4,260 · see citing works
Nanofiber technology: Designing the next generation of tissue engineering scaffolds
Barnes, C. P., Sell, S. A., Boland, E. D., Simpson, D. G., & Bowlin, G. L. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.04.022 · Cited by 1,137 · see citing works
Biodegradable polymer matrix nanocomposites for tissue engineering: A review
Armentano, I., Dottori, M., Fortunati, E., Mattioli, S., & Kenny, J. M. (2010) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2010.06.007 · Cited by 1,001 · see citing works
Functional electrospun nanofibrous scaffolds for biomedical applications
Liang, D., Hsiao, B. S., & Chu, B. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.04.021 · Cited by 974 · see citing works
Pham, Q. P., Sharma, U., & Mikos, A. G. (2006) · Biomacromolecules · doi:10.1021/bm060680j · Cited by 951 · see citing works
Effect of electrospinning parameters on the nanofiber diameter and length
Beachley, V. Z., & Wen, X. (2008) · Materials Science and Engineering C · doi:10.1016/j.msec.2008.10.037 · Cited by 706 · see citing works
Electrospinning for tissue engineering scaffolds
Lannutti, J., Reneker, D., Ma, T., Tomasko, D., & Farson, D. (2007) · Materials Science and Engineering: C · doi:10.1016/j.msec.2006.05.019 · Cited by 693 · see citing works
Recent advance in surface modification for regulating cell adhesion and behaviors
Cai, S., Wu, C., Yang, W., Liang, W., Yu, H., & Liu, L. (2020) · Nanotechnology Reviews · doi:10.1515/ntrev-2020-0076 · Cited by 656 · see citing works
Multifunctional nanostructured PLA materials for packaging and tissue engineering
Armentano, I., Bitinis, N., Fortunati, E., Mattioli, S., Rescignano, N., Verdejo, R., López-Manchado, M., & Kenny, J. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2013.05.010 · Cited by 592 · see citing works
Design, fabrication and characterization of PCL electrospun scaffolds—a review
Cipitria, A., Skelton, A., Dargaville, T. R., Dalton, P. D., & Hutmacher, D. W. (2011) · Journal of Materials Chemistry · doi:10.1039/c0jm04502k · Cited by 628 · see citing works
Elastomeric biomaterials for tissue engineering
Chen, Q., Liang, S., & Thouas, G. A. (2013) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.05.003 · Cited by 564 · see citing works
A review of key challenges of electrospun scaffolds for tissue-engineering applications
Khorshidi, S., Solouk, A., Mirzadeh, H., Mazinani, S., Lagaron, J. M., Sharifi, S., & Ramakrishna, S. (2015) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1978 · Cited by 545 · see citing works
Melt electrospinning today: An opportune time for an emerging polymer process
Brown, T. D., Dalton, P. D., & Hutmacher, D. W. (2016) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2016.01.001 · Cited by 544 · see citing works
DiameterJ: A validated open source nanofiber diameter measurement tool
Hotaling, N. A., Bharti, K., Kriel, H., & Simon, C. G. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.05.015 · Cited by 531 · see citing works
Electrospinning of polymer nanofibers for tissue regeneration
Jiang, T., Carbone, E. J., Lo, K. W. ‐., & Laurencin, C. T. (2014) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2014.12.001 · Cited by 488 · see citing works
He, W., Ma, Z., Yong, T., Teo, W. E., & Ramakrishna, S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.05.049 · Cited by 469 · see citing works
Effects of Humidity and Solution Viscosity on Electrospun Fiber Morphology
Nezarati, R. M., Eifert, M. B., & Cosgriff‐Hernandez, E. (2013) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2012.0671 · Cited by 459 · see citing works
Lowery, J. L., Datta, N., & Rutledge, G. C. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.09.072 · Cited by 448 · see citing works
Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy
Courtney, T. D., Sacks, M. S., Stankus, J. J., Guan, J., & Wagner, W. R. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.02.024 · Cited by 414 · see citing works
Bashur, C. A., Dahlgren, L. A., & Goldstein, A. S. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.07.005 · Cited by 394 · see citing works
Biomaterials for Vascular Tissue Engineering
Ravi, S., & Chaikof, E. L. (2009) · Regenerative Medicine · doi:10.2217/rme.09.77 · Cited by 389 · see citing works
Blakeney, B. A., Tambralli, A., Anderson, J. M., Andukuri, A., Lim, D., Dean, D. R., & Jun, H. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.10.056 · Cited by 370 · see citing works
Chitosan-halloysite Nanotubes Nanocomposite Scaffolds for Tissue Engineering
Liu, M., Wu, C., Jiao, Y., Xiong, S., & Zhou, C. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20084a · Cited by 365 · see citing works
Recent Advances in Analytical Chemistry by 3D Printing
Gross, B., Lockwood, S. Y., & Spence, D. M. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04344 · Cited by 359 · see citing works
Polymeric Nanofibers in Tissue Engineering
Dahlin, R. L., Kasper, F. K., & Mikos, A. G. (2011) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2011.0238 · Cited by 343 · see citing works
Electrospun Micro- and Nanofibers for Sustained Delivery of Paclitaxel to Treat C6 Glioma in Vitro
Xie, J., & Wang, C. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9036-z · Cited by 339 · see citing works
Yordem, O. S., Papila, M., & Menceloǵlu, Y. Z. (2007) · Materials & Design (1980-2015) · doi:10.1016/j.matdes.2006.12.013 · Cited by 336 · see citing works
Applications of electrospun nanofibers
Fang, J., Niu, H., Lin, T., & Wang, X. (2008) · 中国科学通报：英文版 · doi:10.1007/s11434-008-0319-0 · Cited by 321 · see citing works
Supercapacitive Iontronic Nanofabric Sensing
Li, R., Si, Y., Zhu, Z., Guo, Y., Zhang, Y., Pan, N., Sun, G. Z., & Pan, T. (2017) · Advanced Materials · doi:10.1002/adma.201700253 · Cited by 297 · see citing works
A bilayered elastomeric scaffold for tissue engineering of small diameter vascular grafts
Soletti, L., Hong, Y., Guan, J., Stankus, J. J., El‐Kurdi, M. S., Wagner, W. R., & Vorp, D. A. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.06.026 · Cited by 289 · see citing works
Kai, D., Prabhakaran, M. P., Jin, G., & Ramakrishna, S. (2011) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31862 · Cited by 288 · see citing works
The Role of Electrospinning in the Emerging Field of Nanomedicine
Chew, S. Y., Wen, Y., Dzenis, Y. A., & Leong, K. W. (2006) · Current Pharmaceutical Design · doi:10.2174/138161206779026326 · Cited by 278 · see citing works
Current approaches to electrospun nanofibers for tissue engineering
Rim, N. G., Shin, C. S., & Shin, H. (2013) · Biomedical Materials · doi:10.1088/1748-6041/8/1/014102 · Cited by 277 · see citing works
A nanofibrous composite membrane of PLGA–chitosan/PVA prepared by electrospinning
Duan, B., Yuan, X., Zhu, Y. N., Zhang, Y., Li, X., Zhang, Y., & Yao, K. (2006) · European Polymer Journal · doi:10.1016/j.eurpolymj.2006.04.021 · Cited by 271 · see citing works
Hernandez, J. L., & Woodrow, K. A. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202102087 · Cited by 270 · see citing works
Electrospinning for regenerative medicine: a review of the main topics
Braghirolli, D. I., Steffens, D., & Pranke, P. H. L. (2014) · Drug Discovery Today · doi:10.1016/j.drudis.2014.03.024 · Cited by 265 · see citing works
Polypyrrole‐contained electrospun conductive nanofibrous membranes for cardiac tissue engineering
Kai, D., Prabhakaran, M. P., Jin, G., & Ramakrishna, S. (2011) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.33200 · Cited by 258 · see citing works
Moroni, L., Licht, R., de Boer, J., de Wijn, J. R., & van Blitterswijk, C. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.05.027 · Cited by 254 · see citing works
Surface modification of polyester biomaterials for tissue engineering
Jiao, Y., & Cui, F. (2007) · Biomedical Materials · doi:10.1088/1748-6041/2/4/r02 · Cited by 253 · see citing works
Wise, J. K., Yarin, A. L., Megaridis, C. M., & Cho, M. (2008) · Tissue Engineering Part A · doi:10.1089/ten.tea.2008.0109 · Cited by 242 · see citing works
Chen, Q., Zhu, C., & Thouas, G. A. (2012) · Progress in Biomaterials · doi:10.1186/2194-0517-1-2 · Cited by 241 · see citing works
Polyester elastomers for soft tissue engineering
Ye, H., Zhang, K., Kai, D., Li, Z., & Loh, X. J. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00161h · Cited by 240 · see citing works
Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System
Míčková, A., Buzgo, M., Benada, O., Rampichová, M., Fišar, Z., Filová, E., Tesařová, M., Lukáš, D., & Amler, E. (2012) · Biomacromolecules · doi:10.1021/bm2018118 · Cited by 237 · see citing works
Potential of Electrospun Nanofibers for Biomedical and Dental Applications
Zafar, M. S., Najeeb, S., Khurshid, Z., Vazirzadeh, M., Zohaib, S., Najeeb, B., & Sefat, F. (2016) · Materials · doi:10.3390/ma9020073 · Cited by 233 · see citing works
Bioactive scaffolds for bone and ligament tissue
Guarino, V., Causa, F., & Ambrosio, L. (2007) · Expert Review of Medical Devices · doi:10.1586/17434440.4.3.405 · Cited by 226 · see citing works
Milleret, V., Hefti, T., Hall, H., Viola Vogel, B., & Eberli, D. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.07.032 · Cited by 225 · see citing works
Fernández, J., Etxeberria, A., & Sarasua, J.-R. (2012) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2012.01.003 · Cited by 217 · see citing works
Electrospinning of Nanofibers for Tissue Engineering Applications
Liu, H., Ding, X., Zhou, G., Li, P., Wei, X., & Fan, Y. (2013) · Journal of Nanomaterials · doi:10.1155/2013/495708 · Cited by 216 · see citing works
Integrating novel technologies to fabricate smart scaffolds
Moroni, L., de Wijn, J. R., & van Blitterswijk, C. (2008) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856208784089571 · Cited by 215 · see citing works
Mauck, R. L., Baker, B. M., Nerurkar, N. L., Burdick, J. A., Li, W.-J., Tuan, R. S., & Elliott, D. M. (2009) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2008.0652 · Cited by 213 · see citing works
Anisotropic electrical conductivity of MWCNT/PAN nanofiber paper
Ju, E. C., An, K.-H., Kim, K. K., Jeong, S. Y., & Lee, Y. H. (2005) · Chemical Physics Letters · doi:10.1016/j.cplett.2005.07.061 · Cited by 212 · see citing works
Electrospinning of Highly Porous Scaffolds for Cartilage Regeneration
Thorvaldsson, A., Stenhamre, H., Gatenholm, P., & Walkenström, P. (2008) · Biomacromolecules · doi:10.1021/bm701225a · Cited by 211 · see citing works
Fabrication of Large Pores in Electrospun Nanofibrous Scaffolds for Cellular Infiltration: A Review
Zhong, S., Zhang, Y., & Lim, C. T. (2011) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2011.0390 · Cited by 210 · see citing works
Hierarchical starch-based fibrous scaffold for bone tissue engineering applications
Martins, A. M., Chung, S., Pedro, A. J., Sousa, R. A., Marques, A. P., Reis, R. L., & Neves, N. M. (2008) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.132 · Cited by 207 · see citing works
Kwon, I. K., & Matsuda, T. (2005) · Biomacromolecules · doi:10.1021/bm050086u · Cited by 207 · see citing works
Self-citationTijing, L. D., Ruelo, M. T. G., Amarjargal, A., Pant, H. R., Park, C. H., Kim, D., & Kim, C. S. (2012) · Chemical Engineering Journal · doi:10.1016/j.cej.2012.05.005 · Cited by 207 · see citing works
Mechanical properties of single electrospun drug-encapsulated nanofibres
Chew, S. Y., Hufnagel, T. C., Lim, C. T., & Leong, K. W. (2006) · Nanotechnology · doi:10.1088/0957-4484/17/15/045 · Cited by 207 · see citing works
Electrospun Nanostructured Scaffolds for Tissue Engineering Applications
Martins, A. M., Araújo, J. V., Reis, R. L., & Neves, N. M. (2007) · Nanomedicine · doi:10.2217/17435889.2.6.929 · Cited by 206 · see citing works
3D Fiber‐Deposited Electrospun Integrated Scaffolds Enhance Cartilage Tissue Formation
Moroni, L., Schotel, R., Hamann, D., de Wijn, J. R., & van Blitterswijk, C. (2007) · Advanced Functional Materials · doi:10.1002/adfm.200601158 · Cited by 203 · see citing works
Advances in Polymeric Systems for Tissue Engineering and Biomedical Applications
Ravichandran, R., Sundarrajan, S., Venugopal, J. R., Mukherjee, S., & Ramakrishna, S. (2012) · Macromolecular Bioscience · doi:10.1002/mabi.201100325 · Cited by 202 · see citing works
Braided Nanofibrous Scaffold for Tendon and Ligament Tissue Engineering
Barber, J. G., Handorf, A. M., Allee, T. J., & Li, W. (2011) · Tissue Engineering Part A · doi:10.1089/ten.tea.2010.0538 · Cited by 201 · see citing works
Lee, J., Tae, G., Kim, Y. H., Park, I. S., Kim, S.-H., & Kim, S. H. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2007.12.029 · Cited by 200 · see citing works
Degradation Behaviors of Electrospun Resorbable Polyester Nanofibers
Dong, Y., Liao, S., Ngiam, M., Chan, C. K., & Ramakrishna, S. (2009) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2008.0619 · Cited by 200 · see citing works
Balguid, A., Mol, A., van Marion, M. H., Bank, R. A., Bouten, C. V. C., & Baaijens, F. F. (2008) · Tissue Engineering Part A · doi:10.1089/ten.tea.2007.0294 · Cited by 195 · see citing works
Sadeghi, A., Moztarzadeh, F., & Mohandesi, J. A. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.10.022 · Cited by 195 · see citing works
Santos, M. I., Tuzlakoğlu, K., Fuchs, S., Gomes, M. E., Peters, K., Unger, R. E., Pişkın, E., Reis, R. L., & Kirkpatrick, C. J. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.07.033 · Cited by 181 · see citing works
Formation and properties of nylon-6 and nylon-6/montmorillonite composite nanofibers
Li, L., Bellan, L. M., Craighead, H. G., & Frey, M. W. (2006) · Polymer · doi:10.1016/j.polymer.2006.06.049 · Cited by 175 · see citing works
Electrospinning: processing technique for tissue engineering scaffolding
Martins, A. M., Reis, R. L., & Neves, N. M. (2008) · International Materials Reviews · doi:10.1179/174328008x353547 · Cited by 173 · see citing works
Highly Porous Electrospun Nanofibers Enhanced by Ultrasonication for Improved Cellular Infiltration
Lee, J. B., Jeong, S. I., Bae, M. S., Yang, D. H., Heo, D. N., Kim, C. H., Alsberg, E., & Kwon, I. K. (2011) · Tissue Engineering Part A · doi:10.1089/ten.tea.2010.0709 · Cited by 171 · see citing works
Inoguchi, H., Kwon, I. K., Inoue, E., Takamizawa, K., Maehara, Y., & Matsuda, T. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.08.029 · Cited by 166 · see citing works
Self-citationChung, S., Ingle, N. P., Montero, G. A., Kim, S. H., & King, M. W. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.12.007 · Cited by 165 · see citing works
Long term degradation of poly(ɛ-caprolactone) films in biologically related fluids
Peña, J., Corrales, T., Izquierdo-Barba, I., Doadrio, A. L., & Vallet-Regí, M. (2006) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2005.10.016 · Cited by 157 · see citing works
Kuppan, P., Vasanthan, K. S., Sundaramurthi, D., Krishnan, U. M., & Sethuraman, S. (2011) · Biomacromolecules · doi:10.1021/bm200618w · Cited by 157 · see citing works
He, L., Liao, S., Quan, D., Ma, K., Chan, C. K., Ramakrishna, S., & Lu, J. (2010) · Acta Biomaterialia · doi:10.1016/j.actbio.2010.02.039 · Cited by 155 · see citing works
Hajiali, H., Shahgasempour, Naimi-Jamal, M. R., & Peirovi (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s24312 · Cited by 154 · see citing works
Electrospun Gelatin Fibers: Effect of Solvent System on Morphology and Fiber Diameters
Choktaweesap, N., Arayanarakul, K., Aht‐Ong, D., Meechaisue, C., & Supaphol, P. (2007) · Polymer Journal · doi:10.1295/polymj.pj2006190 · Cited by 152 · see citing works
Superamphiphobic nanofibrous membranes for effective filtration of fine particles
Wang, N., Zhu, Z., Sheng, J., Al-Deyab, S. S., Yu, J., & Ding, B. (2014) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2014.04.026 · Cited by 152 · see citing works
Tubular nanofiber scaffolds for tissue engineered small‐diameter vascular grafts
He, W., Ma, Z., Teo, W. E., Dong, Y. X., Robless, P. A., Lim, T. C., & Ramakrishna, S. (2008) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32081 · Cited by 152 · see citing works
Anisotropic Fibrous Scaffolds for Articular Cartilage Regeneration
McCullen, S. D., Autefage, H., Callanan, A., Gentleman, E., & Stevens, M. M. (2012) · Tissue Engineering Part A · doi:10.1089/ten.tea.2011.0606 · Cited by 152 · see citing works
Morphological Characterization of Nanofibers: Methods and Application in Practice
Širc, J., Hobzová, R., Kostina, N. Y., Munzarová, M., Juklíčková, M., Lhotka, M., Kubinová, Š., Zajı́cová, A., & Michálek, J. (2012) · Journal of Nanomaterials · doi:10.1155/2012/327369 · Cited by 152 · see citing works
Xie, J., Peng, C., Zhao, Q., Wang, X., Yuan, H., Yang, L., Li, K., Lou, X., & Zhang, Y. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.10.007 · Cited by 151 · see citing works
Fabrication of silk fibroin blended P(LLA‐CL) nanofibrous scaffolds for tissue engineering
Zhang, K., Wang, H., Huang, C., Su, Y., Mo, X., & Ikada, Y. (2009) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32504 · Cited by 151 · see citing works
Fadaie, M., Mirzaei, E., Geramizadeh, B., & Asvar, Z. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.07.061 · Cited by 150 · see citing works
Materials selection and residual solvent retention in biodegradable electrospun fibers
Nam, J., Huang, Y., Agarwal, S., & Lannutti, J. J. (2007) · Journal of Applied Polymer Science · doi:10.1002/app.27063 · Cited by 149 · see citing works
Kim, H. H., Kim, M. J., Ryu, S. J., Ki, C. S., & Park, Y. H. (2016) · Fibers and Polymers · doi:10.1007/s12221-016-6350-x · Cited by 142 · see citing works
Combinatorial scaffold morphologies for zonal articular cartilage engineering
Steele, J. A. M., McCullen, S. D., Callanan, A., Autefage, H., Accardi, M. A., Dini, D., & Stevens, M. M. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.12.030 · Cited by 140 · see citing works
Biodegradable, thermoplastic polyurethane grafts for small diameter vascular replacements
Bergmeister, H., Seyidova, N., Schreiber, C., Strobl, M., Grasl, C., Walter, I., Meßner, B., Baudis, S., Fröhlich, S. M., Marchetti‐Deschmann, M., et al. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.09.003 · Cited by 132 · see citing works
Stylianopoulos, T., Bashur, C. A., Goldstein, A. S., Guelcher, S. A., & Barocas, V. H. (2008) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2008.01.003 · Cited by 131 · see citing works
Xu, Y., Wu, J., Wang, H., Li, H., Di, N., Song, L., Li, S., Li, D., Xiang, Y., Liu, W., et al. (2013) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2012.0328 · Cited by 129 · see citing works
Inoguchi, H., Tanaka, T., Maehara, Y., & Matsuda, T. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.09.020 · Cited by 129 · see citing works
Self-citationZhang, Y., Venugopal, J. R., Wong, S. Y., Xu, L., Su, B., Ramakrishna, S., & Lim, C. T. (2010) · Tissue Engineering Part A · doi:10.1089/ten.tea.2009.0221 · Cited by 126 · see citing works
A glimpse of biodegradable polymers and their biomedical applications
Shah, T. V., & Vasava, D. V. (2019) · e-Polymers · doi:10.1515/epoly-2019-0041 · Cited by 126 · see citing works
Liu, Y., Ji, Y., Ghosh, K., Clark, R. A. F., Huang, L., & Rafailovich, M. H. (2008) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32165 · Cited by 124 · see citing works
Extraction and Assembly of Tissue-Derived Gels for Cell Culture and Tissue Engineering
Uriel, S., Labay, E., Francis-Sedlak, M. E., Moya, M. L., Weichselbaum, R. R., Ervin, N., Cankova, Z., & Brey, E. M. (2008) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2008.0309 · Cited by 119 · see citing works
Design concepts and strategies for tissue engineering scaffolds
Chung, S., & King, M. W. (2011) · Biotechnology and Applied Biochemistry · doi:10.1002/bab.60 · Cited by 119 · see citing works
Biodegradable Polymer Nanofiber Mesh to Maintain Functions of Endothelial Cells
He, W., Yong, T., Ma, Z. W., Inai, R., Teo, W. E., & Ramakrishna, S. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.2457 · Cited by 118 · see citing works
Healing characteristics of electrospun polyurethane grafts with various porosities
Bergmeister, H., Schreiber, C., Grasl, C., Walter, I., Plasenzotti, R., Stoiber, M., Bernhard, D., & Schima, H. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.12.009 · Cited by 117 · see citing works
Yoshida, M., Roh, K., Mandal, S., Bhaskar, S., Lim, D., Nandivada, H., Deng, X., & Lahann, J. (2009) · Advanced Materials · doi:10.1002/adma.200901971 · Cited by 115 · see citing works
Nanofibrous Poly(lactic acid)/Hydroxyapatite Composite Scaffolds for Guided Tissue Regeneration
Jeong, S. I., Ko, E. K., Yum, J., Jung, C. H., Lee, Y. M., & Shin, H. (2007) · Macromolecular Bioscience · doi:10.1002/mabi.200700107 · Cited by 115 · see citing works
Vaquette, C., Kahn, C. J. F., Frochot, C., Nouvel, C., Six, J., de Isla, N., Luo, L., Cooper-White, J. J., Rahouadj, R., & Wang, X. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32801 · Cited by 114 · see citing works
- Authors
- Keun Kwon, I., Kidoaki, S., & Matsuda, T.
- Affiliations
- Kyushu University (JP)
- Corresponding author
- Matsuda, Takehisa
- ORCID
- Kidoaki, Satoru
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2005-06
- Volume
- 26
- Issue
- 18
- Pages
- 3929-3939
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W1974798445
- Cited by
- 607
- References
- 28
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 12 · 2023: 11 · 2022: 24 · 2021: 16 · 2020: 24 · 2019: 17 · 2018: 30 · 2017: 33 · 2016: 41 · 2015: 32 · 2014: 37 · 2013: 38 · 2012: 47
- FWCI
- 11.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biomaterials (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Topics
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Keywords
- nanofibers, biodegradable copolyesters, poly(L-lactide-co-ε-caprolactone), poly(L-lactic acid), polycaprolactone, fiber diameter, porosity, mechanical properties, cell adhesion, human umbilical vein endothelial cells, endothelial cell proliferation, cell spreading, biomedical applications
- MeSH terms
- Biocompatible Materials, Cell Adhesion, Cells, Cultured, Elasticity, Electrochemistry, Humans, Materials Testing, Particle Size, Polyesters, Tensile Strength, Textiles, Porosity, Cell Culture Techniques, Absorbable Implants, Tissue Engineering, Endothelial Cells, Nanotubes, Cell Proliferation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
