Regular Insulin Versus NPH Insulin for Continuous Enteral Tube Feeding in Hospitalized Patients
Open accessAbstract
There is no standard insulin regimen for treating hyperglycemia in patients receiving continuous enteral tube feeding (TF) in the hospital setting. This study compared the use of regular insulin versus NPH insulin for this purpose. Glucose levels were significantly lower in the regular insulin group than in the NPH insulin group, as were the number of days with hyperglycemia or severe hyperglycemia. There were also fewer insulin injections with regular insulin than with NPH insulin. Thus, use of regular insulin yielded better glycemic control than the use of NPH insulin for covering continuous TF.
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A regular insulin-based plan has been associated with better glycemic management with fewer daily injections in individuals receiving continuous tube feeds.
“However, a regular insulin-based plan has been associated with better glycemic management with fewer daily injections in individuals receiving continuous tube feeds (121).”
From 16. Diabetes Care in the Hospital: Standards of Care in Diabetes—2026 (2026) · cites this paper as [121]
Cites
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Self-citationA practical guide for the management of steroid induced hyperglycaemia in the hospital
Aberer, F., Hochfellner, D. A., Sourij, H., & Mader, J. K. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10102154 · Cited by 110 · see citing works
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16. Diabetes Care in the Hospital: Standards of Care in Diabetes—2026
American Diabetes Association Professional Practice Committee for Diabetes*, Bajaj, M., McCoy, R. G., Balapattabi, K., Bannuru, R. R., Bellini, N. J., Bennett, A. K., Beverly, E. A., Briggs Early, K., ChallaSivaKanaka, S., et al. (2026) · Diabetes Care · doi:10.2337/dc26-s016 · Cited by 80 · see citing works
Self-citation
- Authors
- Kalangi, S. T., Bokka, S. M., Anand, S., & Garg, R.
- Affiliations
- Harbor–UCLA Medical Center (US)
- Corresponding author
- Garg, Rajesh
- ORCID
- Garg, Rajesh
- Venue
- Clinical Diabetes
- Publisher
- American Diabetes Association
- Published
- 2025-04-23
- Volume
- 43
- Issue
- 4
- Pages
- 504-512
- ISSN
- 0891-8929 (ISSN-L)
- 1945-4953
- PMC
- PMC12547051
- OpenAlex
- W4410154698
- Cited by
- 1
- References
- 4
- Citations by year
- 2026: 1
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Diabetes (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Keywords
- regular insulin, NPH insulin, hyperglycemia, glycemic control, insulin regimens, hospitalized patients, insulin injection
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