Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes

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Items 301–400 of 569

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2. Role of Skeletal Muscle Mitochondrial Density on Exercise‐Stimulated Lipid Oxidation
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3. The effect of exercise on skeletal muscle fibre type distribution in obesity: From cellular levels to clinical application
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4. Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age‐specific manner
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5. Exercise in the Prevention and Treatment of Type 2 Diabetes
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6. Skeletal muscle performance in metabolic disease: Microvascular or mitochondrial limitation or both?
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7. Twenty-Four Hour Total and Dietary Fat Oxidation in Lean, Obese and Reduced-Obese Adults with and without a Bout of Exercise
   Audrey Bergouignan, Elizabeth H. Kealey, Stacy L. Schmidt, Matthew R. Jackman, Daniel H. Bessesen · 2014 · PLoS ONE
8. Progression of type 2 diabetes in GK rats affects muscle and liver mitochondria differently: pronounced reduction of complex II flux is observed in liver only
   Wenche Jørgensen, Peter Jelnes, Kasper A. Rud, Lillian L. Hansen, Niels Grunnet, Bjørn Quistorff · 2012 · American Journal of Physiology-Endocrinology and Metabolism
9. Reduced skeletal muscle phosphocreatine concentration in type 2 diabetic patients: a quantitative image-based phosphorus-31 MR spectroscopy study
   Erika M. Ripley, Geoffrey D. Clarke, Vala Hamidi, ROBERT A. MARTINEZ, F Settles, Carolina Solis‐Herrera, Shengwen Deng, Muhammad A Abdul‐Ghani, Devjit Tripathy, Ralph A. DeFronzo · 2018 · American Journal of Physiology-Endocrinology and Metabolism
10. Single‐leg exercise training augments in vivo skeletal muscle oxidative flux and vascular content and function in adults with type 2 diabetes
    Rebecca L. Scalzo, Irene E. Schauer, Deirdre Rafferty, Leslie A. Knaub, Nina Kvaratskhelia, Taro Kaelix Johnson, Gregory B. Pott, Layla A. Abushamat, Mary O. Whipple, Amy G. Huebschmann et al. · 2021 · The Journal of Physiology
11. RNA Sequencing Reveals a Slow to Fast Muscle Fiber Type Transition after Olanzapine Infusion in Rats
    Christopher J. Lynch, Yuping Xu, András Sándor Hajnal, Anna C. Salzberg, Yuka Imamura Kawasawa · 2015 · PLoS ONE
12. The Pathophysiology of Obesity and Obesity-Related Disease
    Robert W. O’Rourke · 2019 · Springer eBooks
13. The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders
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14. A Narrative Review of Non-Pharmacological Strategies for Managing Sarcopenia in Older Adults with Cardiovascular and Metabolic Diseases
    T. Ispoglou, Oliver J. Wilson, D. McCullough, Luke Aldrich, P. Ferentinos, G. Lyall, A. Stavropoulos-Kalinoglou, L. Duckworth, Meghan A. Brown, L. Sutton et al. · 2023 · Biology
15. Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity
    Katie L. Whytock, Maria F. Pino, Yifei Sun, Gongxin Yu, Flávia Giolo de Carvalho, Reichelle X. Yeo, Rick B. Vega, Gaganvir Parmar, Adeline Divoux, N Kapoor et al. · 2023 · American Journal of Physiology-Endocrinology and Metabolism
16. Muscle-UCP3 in the regulation of energy metabolism
    Lucio Della Guardia, Livio Luzi, Roberto Codella · 2024 · Mitochondrion
17. Subcellular lipid droplet distribution in red and white muscles in the obese Zucker rat
    James Lally, Laelie A. Snook, Xiao Han, Adrian Chabowski, Arend Bonen, Graham P. Holloway · 2011 · Diabetologia
18. No Influence of Overweight/Obesity on Exercise Lipid Oxidation: A Systematic Review
    Avigdor D. Arad, Anthony J. Basile, Jeanine Albu, Fred J. DiMenna · 2020 · International Journal of Molecular Sciences
19. Pathophysiology of the Metabolic Syndrome
    John J. Nolan, Donal J. O’Gorman · 2013 · Springer eBooks
20. Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia
    Steen Larsen, Celena Scheede‐Bergdahl, Thomas Whitesell, Robert Boushel, Andreas Bergdahl · 2015 · Physiological Reports
21. Enhanced Skeletal Muscle Lipid Oxidative Efficiency in Insulin-Resistant vs Insulin-Sensitive Nondiabetic, Nonobese Humans
    José Eduardo Galgani, Karla Yohannessen Vásquez, Guillermo Watkins, Aude Dupuy, Justine Bertrand‐Michel, Thierry Levade, Cédric Moro · 2013 · The Journal of Clinical Endocrinology & Metabolism
22. Losartan modulates muscular capillary density and reverses thiazide diuretic-exacerbated insulin resistance in fructose-fed rats
    Qi Guo, Takefumi Mori, Yue Jiang, Chunyan Hu, Yusuke Ohsaki, Yoshimi Yoneki, Takashi Nakamichi, Susumu Ogawa, Hiroshi Sato, Sadayoshi Ito · 2011 · Hypertension Research
23. Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise
    Paula Michelle Miotto, Gregory R. Steinberg, Graham P. Holloway · 2016 · Biochemical Journal
24. Heat exposure does not alter eccentric exercise-induced increases in mitochondrial calcium and respiratory dysfunction
    Ben Rattray, Corinne Caillaud, Patricia A. Ruell, M. W. Thompson · 2011 · European Journal of Applied Physiology
25. A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in Type 2 diabetes mellitus
    Ines Pagel, Daniel R. Schwartz, Ross A Arena, Diane C. Minerbi, D. Johnson, Myron A. Waclawiw, Richard O. Cannon, Robert S. Balaban, Dorothy J. Tripodi, Michael N. Sack · 2007 · American Journal of Physiology-Heart and Circulatory Physiology
26. Decrement in resting and insulin‐stimulated soleus muscle mitochondrial respiration is an early event in diet‐induced obesity in mice
    Henver S. Brunetta, Gabriela Cristina de Paula, Jade de Oliveira, Eduarda Lopes Martins, Gustavo Jorge dos Santos, Antônio Galina, Alex Rafacho, Andreza Fabro De Bem, Everson Araújo Nunes · 2018 · Experimental Physiology
27. Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities
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28. Specific NOX4 Inhibition Preserves Mitochondrial Function and Dampens Kidney Dysfunction Following Ischemia–Reperfusion-Induced Kidney Injury
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29. Maximal Fat Oxidation Rate during Exercise in Korean Women with Type 2 Diabetes Mellitus
    Min Hwa Suk, Yeo-Jin Moon, Sung Woo Park, Cheol‐Young Park, Yun A Shin · 2015 · Diabetes & Metabolism Journal
30. Is GPR119 agonism an appropriate treatment modality for the safe amelioration of metabolic diseases?
    Lauren M. Cornall, Michael L. Mathai, Deanne Helena Hryciw, Andrew J. McAinch · 2013 · Expert Opinion on Investigational Drugs
31. 31P MR Spectroscopy and Computational Modeling Identify a Direct Relation between Pi Content of an Alkaline Compartment in Resting Muscle and Phosphocreatine Resynthesis Kinetics in Active Muscle in Humans
    Joep W. M. van Oorschot, Joep P. J. Schmitz, ANDREW G. WEBB, Klaas Nicolay, Jeroen A. L. Jeneson, Hermien E. Kan · 2013 · PLoS ONE
32. Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men
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33. Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors
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34. Inhibitory Regulation of FOXO1 in PPARδ Expression Drives Mitochondrial Dysfunction and Insulin Resistance
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35. Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine
    Silvia Sookoian, Carlos Jose Pirola · 2013 · Current Diabetes Reports
36. A transient increase in lipid peroxidation primes preadipocytes for delayed mitochondrial inner membrane permeabilization and ATP depletion during prolonged exposure to fatty acids
    Carlyle Rogers, Barbara Davis, Peter Darrell Neufer, Michael P. Murphy, Ethan J. Anderson, Jacques Robidoux · 2013 · Free Radical Biology and Medicine
37. The effect of blood glucose regulation on sarcopenia parameters in obese and diabetic patients
    Zeynel Abidin Öztürk · 2017 · Turkish Journal of Physical Medicine and Rehabilitation
38. Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction
    Takahiro Abe, Takashi Yokota, Arata Fukushima, Naoya Kakutani, Takashi Katayama, Ryosuke Shirakawa, Satoshi Maekawa, Hideo Nambu, Yoshikuni Obata, Katsuma Yamanashi et al. · 2020 · Cardiovascular Diabetology
39. Proteomic study of skeletal muscle in obesity and type 2 diabetes: progress and potential
    Rikke Kruse, Kurt Højlund · 2018 · Expert Review of Proteomics
40. Skeletal Muscle Consequences of Phosphatidylethanolamine Synthesis Deficiency
    Sophie Grapentine, Rathnesh K. Singh, Marica Bakovic · 2023 · Function
41. Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress
    Mahesh Kumar Verma, Aggunda Nagaraju Yateesh, Korrapati Neelima, Niketa Pawar, Kandoor Sandhya, Jayaram Poornima, Mudigere N Lakshmi, Sivakumaran Yogeshwari, Puttrevana M Pallavi, Anup Mammen Oommen et al. · 2014 · SpringerPlus
42. The Mitochondrial Proteomic Signatures of Human Skeletal Muscle Linked to Insulin Resistance
    Rikke Kruse, Navid Sahebekhtiari, Kurt Højlund · 2020 · International Journal of Molecular Sciences
43. Depressed mitochondrial function and electron transport Complex II-mediated H 2 O 2 production in the cortex of type 1 diabetic rodents
    Subir Roy Chowdhury, Jelena Djordjevic, Ella A. Thomson, Darrell R. Smith, Benedict C. Albensi, Paul Fernyhough · 2018 · Molecular and Cellular Neuroscience
44. Effect of Acute Aerobic Exercise and Rapamycin Treatment on Autophagy in Peripheral Blood Mononuclear Cells of Adults With Prediabetes
    James J. McCormick, Kelli E. King, Karol Dokładny, Christine M. Mermier · 2019 · Canadian Journal of Diabetes
45. Skeletal muscle mitochondrial dysfunction is associated with increased Gdf15 expression and circulating GDF15 levels in aged mice
    J. Chen, JAKE KASTROLL, Fiona M. Bello, Martha M. Pangburn, A. Murali, P. M. Smith, K. Rychcik, Kelly E. Loughridge, Amber M. Vandevender, Nikolaos L. Dedousis et al. · 2025 · Scientific Reports
46. Effects of two workload-matched high intensity interval training protocols on regulatory factors associated with mitochondrial biogenesis in the soleus muscle of diabetic rats
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47. Improvement of Platelet Respiration by Cell–Permeable Succinate in Diabetic Patients Treated with Statins
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48. Strength training improves insulin resistance and differently affects mitochondria in skeletal muscle and visceral adipose tissue in high-fat fed mice
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49. Gintonin-enriched fraction protects against sarcopenic obesity by promoting energy expenditure and attenuating skeletal muscle atrophy in high-fat diet-fed mice
    Heegu Jin, Hyun‐Ji Oh, Seung-Yeol Nah, Boo-Yong Lee · 2021 · Journal of Ginseng Research
50. Insulin-stimulated mitochondrial adenosine triphosphate synthesis is blunted in skeletal muscles of high-fat–fed rats
    Brittany Yerby, Richard W. Deacon, Valérie Beaulieu, Jinsheng Liang, Jiaping Gao, Didier Laurent · 2008 · Metabolism
51. Adipose Mitochondrial Complex I Deficiency Modulates Inflammation and Glucose Homeostasis in a Sex-Dependent Manner
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52. BrainPhys Neuronal Media Support Physiological Function of Mitochondria in Mouse Primary Neuronal Cultures
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53. Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan
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54. Tissue-Specific Effects of Bariatric Surgery Including Mitochondrial Function
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55. Autophagy activation, not peroxisome proliferator‐activated receptor γ coactivator 1α, may mediate exercise‐induced improvements in glucose handling during diet‐induced obesity
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56. Role of CaMKII in the regulation of fatty acids and lipid metabolism
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57. White adipose tissue mitochondrial bioenergetics in metabolic diseases
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58. Targeting Intramyocellular Lipids to Improve Aging Muscle Function
    Russ, David W., Manickam, Ravikumar, Tipparaju, Srinivas M. · 2025 · Lipids in Health and Disease
59. The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome
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60. A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle
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61. The Epidemic of Type 2 Diabetes Mellitus: Its Links to Obesity, Insulin Resistance, and Lipotoxicity
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62. Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications
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63. HORMONE-DEPENDENT AND HORMONE-INDEPENDENT CONTROL OF METABOLIC AND DEVELOPMENTAL FUNCTIONS OF MALATE DEHYDROGENASE – Review
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64. Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes
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65. The dynamic equilibrium between ATP synthesis and ATP consumption is lower in isolated mitochondria from myotubes established from type 2 diabetic subjects compared to lean control
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66. Application of mass spectrometry based proteomics to understand diabetes: A special focus on interactomics
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68. High-throughput muscle fiber typing from RNA sequencing data
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69. Role of Quercetin in DNA Repair: Possible Target to Combat Drug Resistance in Diabetes
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70. Rats Bred for Low Aerobic Capacity Become Promptly Fatigued and Have Slow Metabolic Recovery after Stimulated, Maximal Muscle Contractions
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71. Revisiting the contribution of mitochondrial biology to the pathophysiology of skeletal muscle insulin resistance
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73. Effects of Combined Inorganic Nitrate and Nitrite Supplementation on Cardiorespiratory Fitness and Skeletal Muscle Oxidative Capacity in Type 2 Diabetes: A Pilot Randomized Controlled Trial
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76. Pathogenesis of Type 2 Diabetes Mellitus
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78. The Response of Mitochondrial Respiration and Quantity in Skeletal Muscle and Adipose Tissue to Exercise in Humans with Prediabetes
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81. Deteriorated regional calf microcirculation measured by contrast-free MRI in patients with diabetes mellitus and relation with physical activity
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