Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 757

The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

Omentin Plasma Levels and Gene Expression Are Decreased in Obesity

Open access
de Souza Batista, Celia M., Yang, Rong-Ze, Lee, Mi-Jeong, Glynn, Nicole M., Yu, Dao-Zhan, Pray, Jessica, Ndubuizu, Kelechi, Patil, Susheel, Schwartz, Alan, Kligman, Mark, Fried, Susan K., Gong, Da-Wei, Shuldiner, Alan R., Pollin, Toni I., McLenithan, John C.·2007·Diabetes

Abstract

Central obesity and the accumulation of visceral fat are risk factors for the development of type 2 diabetes and cardiovascular disease. Omentin is a protein expressed and secreted from visceral but not subcutaneous adipose tissue that increases insulin sensitivity in human adipocytes. To determine the impact of obesity-dependent insulin resistance on the regulation of two omentin isoforms, gene expression and plasma levels were measured in lean, overweight, and obese subjects. Omentin 1 was shown to be the major circulating isoform in human plasma. Lean subjects had significantly higher plasma omentin 1 levels than obese and overweight subjects. In addition, higher plasma omentin 1 levels were detected in women compared with men. Plasma omentin 1 levels were inversely correlated with BMI, waist circumference, leptin levels, and insulin resistance as measured by homeostasis model assessment and positively correlated with adiponectin and HDL levels. Both omentin 1 and omentin 2 gene expression were decreased with obesity and were highly correlated with each other in visceral adipose tissue. In summary, decreased omentin levels are associated with increasing obesity and insulin resistance. Therefore, omentin levels may be predictive of the metabolic consequences or co-morbidities associated with obesity.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.2337/db06-1506

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 44 references

Cited by

See all 757

Metadata

Authors
de Souza Batista, C. M., Yang, R.-Z., Lee, M.-J., Glynn, N. M., Yu, D.-Z., Pray, J., Ndubuizu, K., Patil, S., Schwartz, A., Kligman, M., Fried, S. K., Gong, D.-W., Shuldiner, A. R., Pollin, T. I., & McLenithan, J. C.
Venue
Diabetes
Published
2007-06-01
Volume
56
Issue
6
Pages
1655-1661
ISSN
  • 0012-1797 (ISSN-L)
  • 1939-327X
OpenAlex
W2124589753
Cited by
757
References
44
FWCI
11.93
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Omentin Plasma Levels and Gene Expression Are Decreased in Obesity. https://app.cochat.ai/papers/10.2337/db06-1506
The paper
de Souza Batista, C. M., Yang, R.-Z., Lee, M.-J., Glynn, N. M., Yu, D.-Z., Pray, J., Ndubuizu, K., Patil, S., Schwartz, A., Kligman, M., Fried, S. K., Gong, D.-W., Shuldiner, A. R., Pollin, T. I., & McLenithan, J. C. (2007). Omentin Plasma Levels and Gene Expression Are Decreased in Obesity. Diabetes. https://doi.org/10.2337/db06-1506

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.