Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

Strawbridge, Rona J., Dupuis, Josée, Prokopenko, Inga, Barker, Adam, Ahlqvist, Emma, Rybin, Denis, Petrie, John R., Travers, Mary E. +100 more·2011·Diabetes

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  14. Prediction of type 2 diabetes mellitus onset using logistic regression-based scorecards
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  18. Fine-tuning of Genome-Wide Polygenic Risk Scores and Prediction of Gestational Diabetes in South Asian Women
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  19. Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations
    Khairul Anwar Zarkasi, Nor Azian Abdul Murad, Norfazilah Ahmad, Rahman Jamal, Noraidatulakma Abdullah · 2022 · International Journal of Environmental Research and Public Health
  20. Personalized cardiovascular medicine: concepts and methodological considerations
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  22. Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing
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    Andrew P. Morris · 2018 · Current Opinion in Genetics & Development
  25. Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice
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    Gaëlle Carrat, Elizabeth Haythorne, Alejandra Tomás, Leena Haataja, Andreas Müller, Peter R. Arvan, Alexandra Piunti, Kaiying Cheng, Mutian Huang, Timothy J. Pullen et al. · 2020 · Molecular Metabolism
  30. Reduction in Tcf7l2 Expression Decreases Diabetic Susceptibility in Mice
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  31. Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes
    Miriam S. Udler, Jaegil Kim, Marcin von Grotthuss, Sílvia Bonàs‐Guarch, Josep Maria Mercader, Joanne B. Cole, Joshua Chiou, Christopher D. Anderson, Michael Boehnke, Markku Laakso et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Association of KCNQ1 and KLF14 polymorphisms and risk of type 2 diabetes mellitus: A global meta-analysis
    Jinjin Wang, Jianfeng Zhang, Jie Shen, Dongsheng Hu, Guoli Yan, Xiaohui Liu, Xueqin Xu, Lanying Pei, Yanfang Li, Chunyang Sun · 2014 · Human Immunology
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    Zheng Ye, Christopher Gillson, Matt Sims, Kay‐Tee Khaw, Magdalena Płotka, Joanna Poulton, Claudia Langenberg, Nicholas J. Wareham · 2013 · Diabetologia
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    Suzuki Ken, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Nigel W. Rayner, Ozvan Bocher et al. · 2023 · Yearbook of pediatric endocrinology
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  37. New insights from monogenic diabetes for “common” type 2 diabetes
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  38. Identification of Novel Type 2 Diabetes Candidate Genes Involved in the Crosstalk between the Mitochondrial and the Insulin Signaling Systems
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  39. Functional Consequences of a Novel Variant of PCSK1
    Lindsay A. Pickett, Michael Yourshaw, Valeria Albornoz, Zijun Chen, R. Sergio Solórzano-Vargas, Stanley F. Nelson, Martı́n G. Martı́n, Iris Lindberg · 2013 · PLoS ONE
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    Li, Yang Eric, Preissl, Sebastian, Hou, Xiaomeng, Zhang, Ziyang, Zhang, Kai, Fang, Rongxin, Qiu, Yunjiang, Poirion, Olivier, Li, Bin, Liu, Hanqing et al. · 2020
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    Chunbo Yang, Sophia Kelaini, Rachel Caines, Andriana Margariti · 2018 · Frontiers in Physiology
  43. Gaining insight into metabolic diseases from human genetic discoveries
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  44. Altered islet prohormone processing: a cause or consequence of diabetes?
    Adam Ramzy, Timothy J. Kieffer · 2021 · Physiological Reviews
  45. PCSK1 rs6232 Is Associated with Childhood and Adult Class III Obesity in the Mexican Population
    Marisela Villalobos‐Comparán, Hugo Villamil‐Ramírez, María Teresa Villarreal-Molina, Elena Larrieta‐Carrasco, Paola León‐Mimila, Sandra Romero‐Hidalgo, Leonor Jacobo‐Albavera, Adriana E Liceaga-Fuentes, Francisco Campos‐Pérez, Blanca Estela López-Contreras et al. · 2012 · PLoS ONE
  46. GARFIELD - GWAS Analysis of Regulatory or Functional Information Enrichment with LD correction
    Valentina Iotchkova, Graham R. S. Ritchie, Matthias Geihs, Sandro Morganella, Josine L. Min, Klaudia Walter, Nicholas John Timpson, Ian Dunham, Ewan Birney, Nicole Soranzo · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
  47. Single cell chromatin accessibility reveals pancreatic islet cell type- and state-specific regulatory programs of diabetes risk
    Chiou, Joshua, Zeng, Chun, Cheng, Zhang, Han, Jee Yun, Schlichting, Michael, Huang, Serina, Wang, Jinzhao, Sui, Yinghui, Deogaygay, Allison, Okino, Mei-Lin et al. · 2019
  48. Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion
    Hanieh Yaghootkar, Alena Stančáková, Rachel M. Freathy, Jagadish Vangipurapu, Michael N. Weedon, Weijia Xie, Andrew R. Wood, Ele Ferrannini, Andrea Mari, Susan M. Ring et al. · 2015 · Diabetes
  49. Five stages of progressive β-cell dysfunction in the laboratory Nile rat model of type 2 diabetes
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  50. Negative Effects of Age at Menarche on Risk of Cardiometabolic Diseases in Adulthood: A Mendelian Randomization Study
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    Michelle M. J. Mens, Silvana C. E. Maas, Jaco M. Klap, Gerrit Jan Weverling, Paul R. Klatser, Just P. J. Brakenhoff, Joyce B. J. van Meurs, André Gerardus Uitterlinden, M. Arfan Ikram, Maryam Kavousi et al. · 2020 · Frontiers in Genetics
  52. Nutrient regulation of the islet epigenome controls adaptive insulin secretion
    Matthew Wortham, Fenfen Liu, Austin R. Harrington, Johanna Y. Fleischman, Martina Wallace, Francesca Mulas, Medhavi Mallick, Nicholas K. Vinckier, Benjamin R. Cross, Joshua Chiou et al. · 2023 · Journal of Clinical Investigation
  53. GWAS on prolonged gestation (post-term birth): analysis of successive Finnish birth cohorts
    William S. Schierding, Jisha Antony, Ville Karhunen, Marja Vääräsmäki, Steve Franks, Paul Elliott, Eero Kajantie, Sylvain P Sebert, Alexandra I. F. Blakemore, Julia A. Horsfield et al. · 2017 · Journal of Medical Genetics
  54. Defining type 2 diabetes polygenic risk scores through colocalization and network-based clustering of metabolic trait genetic associations
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  55. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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  56. Omics Approaches in Adipose Tissue and Skeletal Muscle Addressing the Role of Extracellular Matrix in Obesity and Metabolic Dysfunction
    Augusto Anguita‐Ruiz, Mireia Bustos‐Aibar, Julio Plaza‐Díaz, Andrea Méndez-Gutiérrez, Jesús Alcalá‐Fdez, Concepción María Aguilera, Francisco Javier Ruiz‐Ojeda · 2021 · International Journal of Molecular Sciences
  57. Genetic underpinnings of left superior temporal gyrus thickness in patients with schizophrenia
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  58. IG20/MADDPlays a Critical Role in Glucose-Induced Insulin Secretion
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  60. Genetics of canine myxomatous mitral valve disease
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  61. The PARK2 gene is involved in the maintenance of pancreatic β-cell functions related to insulin production and secretion
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  62. Association of the rs6235 variant in the proprotein convertase subtilisin/kexin type 1 (PCSK1) gene with obesity and related traits in a Taiwanese population
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  65. Effects of ZnT8 on epithelial-to-mesenchymal transition and tubulointerstitial fibrosis in diabetic kidney disease
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  66. Genetics of Type 2 Diabetes: Opportunities for Precision Medicine
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  67. Association between type 2 diabetes and amyotrophic lateral sclerosis
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  68. Discovery and Validation of Prognostic Biomarker Models to Guide Triage among Adult Dengue Patients at Early Infection
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  69. The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis
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  70. A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes
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  71. Genetically determined schizophrenia is not associated with impaired glucose homeostasis
    Renato A Polimanti, Joel E. Gelernter, Dan Joseph Stein · 2017 · Schizophrenia Research
  72. Genetic Approaches to the Study of Gene Variants and Their Impact on the Pathophysiology of Type 2 Diabetes
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  73. Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits
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  74. Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes
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  75. Interactions between genetic background, insulin resistance and β‐cell function
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  76. Inhibition of secreted frizzled-related protein 5 improves glucose metabolism
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  77. Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice
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  78. Genetic advances of type 2 diabetes in Chinese populations
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  79. Is experimentally induced pain associated with socioeconomic status? Do poor people hurt more?
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  80. Dissecting the association of autophagy-related genes with cardiovascular diseases and intermediate vascular traits: A population-based approach
    Eliana Portilla-Fernández, Mohsen Ghanbari, Joyce B. J. van Meurs, A.H. Jan Danser, Oscar H. Franco, Taulant Muka, Anton J.M. Roks, Abbas Dehghan · 2019 · PLoS ONE
  81. Yeast as a Model to Find New Drugs and Drug Targets for VPS13-Dependent Neurodegenerative Diseases
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  82. Dietary Insulin Index and Insulin Load in Relation to Endometrial Cancer Risk in the Nurses' Health Study
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  83. Mendelian randomization studies of biomarkers and type 2 diabetes
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  84. Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research
    Ming Hu, Ines Cherkaoui, Shivani Misra, Guy A. Rutter · 2020 · Frontiers in Endocrinology
  85. Identifying causality, genetic correlation, priority and pathways of large-scale complex exposures of breast and ovarian cancers
    Shucheng Si, Jiqing Li, Marlvin Anemey Tewara, Hongkai Li, Xinhui Liu, Yunxia Li, Xiaolu Chen, Congcong Liu, Tonghui Yuan, Wenchao Li et al. · 2021 · British Journal of Cancer
  86. Defective Transport of the Obesity Mutant PC1/3 N222D Contributes to Loss of Function
    Yogikala Prabhu, Elías H. Blanco, Ming Rong Liu, Juan R. Peinado, Matthew C. Wheeler, Nicholas Gekakis, Peter R. Arvan, Iris Lindberg · 2014 · Endocrinology
  87. Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine
    Silvia Sookoian, Carlos Jose Pirola · 2013 · Current Diabetes Reports
  88. Common Genetic Variants of Surfactant Protein-D (SP-D) Are Associated with Type 2 Diabetes
    Neus Pueyo, Francisco José Ortega, Josep Maria Mercader, José María Moreno‐Navarrete, Mònica Sabater, Sílvia Bonàs‐Guarch, Patricia Botas, Elías Delgado, Wifredo Ricart, María T. Martinez-Larrad et al. · 2013 · PLoS ONE
  89. Association of four new candidate genetic variants with Parkinson's disease in a Han Chinese population
    Ling Wang, Lan Cheng, Nan‐Nan Li, Wen‐Juan Yu, Xiao‐Yi Sun, Rong Peng · 2015 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  90. Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin
    Md Rafiqul Islam, Dale R. Nyholt · 2023 · Human Genetics
  91. La-related protein 6 controls ciliated cell differentiation
    Zarko Manojlovic, Ryan Earwood, Akiko Kato, Diana Laura García Pérez, Oscar A. Cabrera, Ruth Didier, Timothy L. Megraw, Branko Stefanovic, Yoichi Kato · 2017 · Cilia
  92. Functional characteristics of novel pancreatic Pax6 regulatory elements
    Adam Buckle, Ryu-Suke Nozawa, D. Kleinjan, N. Gilbert · 2018 · Human Molecular Genetics
  93. Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity
    Pieter Stijnen, Bas Brouwers, Ellen Dirkx, Bruno Ramos‐Molina, Leentje Van Lommel, Frans C Schuit, Lieven Thorrez, Jeroen Declercq, John W.M. Creemers · 2016 · International Journal of Obesity
  94. Human physiology of genetic defects causing beta-cell dysfunction.
    J. Kettunen, T. Tuomi · 2020 · Journal of Molecular Biology
  95. From Mice to Humans
    Fiona McMurray, Lee Moir, Roger Cox · 2012 · Current Diabetes Reports
  96. Genome-Wide Association Study Identifies Possible Genetic Risk Factors for Colorectal Adenomas
    Todd L. Edwards, Martha J. Shrubsole, Qiuyin Cai, Guoliang Li, Qi Dai, Douglas Kevin Rex, Thomas M. Ulbright, Zhenming Fu, Ryan H. Delahanty, Harvey J. Murff et al. · 2013 · Cancer Epidemiology Biomarkers & Prevention
  97. New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats
    Daiki Sasaki, Jun Kotoh, Risa Watadani, Kozo Matsumoto · 2015 · Mammalian Genome
  98. Cumulative Effect and Predictive Value of Genetic Variants Associated with Type 2 Diabetes in Han Chinese: A Case-Control Study
    Yun Qian, Feng Lu, Meihua Dong, Yudi Lin, Huizhang Li, Juncheng Dai, Guangfu Jin, Zhibin Hu, Hongbing Shen · 2015 · PLoS ONE
  99. PICK1 is essential for insulin production and the maintenance of glucose homeostasis
    Jia Li, Zhuo Mao, Jiandong Huang, Jun Xia · 2018 · Molecular Biology of the Cell
  100. Gene-Physical Activity Interactions and Their Impact on Diabetes
    Tuomas O. Kilpeläinen, Paul W. Franks · 2014 · Medicine and sport science/Medicine and sport