Human β-Cell Proliferation and Intracellular Signaling: Part 3

Stewart, Andrew F., Hussain, Mehboob A., García-Ocaña, Adolfo, Vasavada, Rupangi C., Bhushan, Anil, Bernal-Mizrachi, Ernesto, Kulkarni, Rohit N.·2015·Diabetes

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  1. SPOCK2 controls the proliferation and function of immature pancreatic β-cells through MMP2
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  2. Recent advances in pancreatic α-cell transdifferentiation for diabetes therapy
    Yanjiao Li, Jinyu Zhu, Congyang Yue, Siyuan Song, Limin Tian, Yi Wang · 2025 · Frontiers in Immunology
  3. SNAPIN Regulates Cell Cycle Progression to Promote Pancreatic β Cell Growth
    Mengxue Jiang, Zhijian Kuang, Yaohui He, Yin Cao, Ting-Yan Yu, Jidong Cheng, Wen Liu, Wei Wang · 2021 · Frontiers in Endocrinology
  4. Beta-Cell Golgi Stress Response to Lipotoxicity and Glucolipotoxicity: A Preliminary Study of a Potential Mechanism of Beta-Cell Failure in Posttransplant Diabetes and Intraportal Islet Transplant
    Neslihan Başçıl Tütüncü, Hasibe Verdi, Yaprak Yalçın, Hatice Pınar Baysan Çebi, Sibel Tulgar Kınık, Tanju Tütüncü, Fatma Belgin Ataç · 2022 · Experimental and Clinical Transplantation
  5. Chemerin as an Inducer of β Cell Proliferation Mediates Mitochondrial Homeostasis and Promotes β Cell Mass Expansion
    Min Li, Ruifan Zhang, Qian Ge, Lingzhi Yue, Dan Ma, Firas Khattab, Wenhua Xie, Yewei Cui, Patrick Gilon, Xueya Zhao et al. · 2023 · International Journal of Molecular Sciences
  6. New-found brake calibrates insulin action in β-cells
    Rohit Kulkarni · 2021 · Nature
  7. The Values and Perspectives of Organoids in the Field of Metabolic Syndrome
    Tan Chen, Min Ding, Yun‐Wen Zheng · 2023 · International Journal of Molecular Sciences
  8. Regeneration of β-cells of the islet apparatus of the pancreas. Literature review
    Timofey E. Pylaev, Irina V. Smyshlyaeva, Era B. Popyhova · 2022 · Diabetes Mellitus
  9. The protein deacetylase SIRT2 exerts metabolic control over adaptive β cell proliferation
    Matthew Wortham, Bastian Ramms, Chun Zeng, Jacqueline R. Benthuysen, Somesh Sai, Dennis P. Pollow, Fenfen Liu, Michael Schlichting, Austin R. Harrington, Bradley Liu et al. · 2025 · Journal of Clinical Investigation
  10. Various strategies to induce beta cell neogenesis: a comprehensive review for unravelling the potential future therapy for curing diabetes
    Anjali S. Patel, B. Rajgopal, Manisha Jaiswal · 2025 · Growth Factors
  11. Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis
    Jeongkyung Lee, Ruya Liu, Byung S. Kim, Yiqun Zhang, Feng Li, Rajaganapti Jagannathan, Ping Yang, Vinny Negi, Joseph Danvers, Eliana Melissa Perez-Garcia et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety
    Okka Scholz, Elena Huß, Silke Otter, Diran Herebıan, Anna B. Hamacher, Laura M. Levy, Stanimira Hristeva, Miguel Sanz, Haresh Ajani, Alfredo Rodriguez Puentes et al. · 2023 · Molecular Metabolism
  13. 3D evaluation of the extracellular matrix of hypoxic pancreatic islets using light sheet fluorescence microscopy
    Matias Ramirez, Estelle Bastien, Heeyoung Chae, Pierre Gianello, Patrick Gilon, Caroline Bouzin · 2024 · Islets
  14. Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice
    Kristy Ou, Jia Zhang, Yang Jiao, Zhao V. Wang, P. E. Scherer, Klaus H. Kaestner · 2018 · Molecular Metabolism
  15. Insulin/IGF signaling in islet biology and its therapeutic implications
    Hyunki Kim, Rohit N. Kulkarni · 2026 · Endocrine Reviews
  16. Harnessing Immune Cells to Enhance β-Cell Mass in Type 1 Diabetes
    Ercument Dirice, Rohit Kulkarni · 2016 · Journal of Investigative Medicine
  17. Alpha- and Beta-Cell Proliferation and Extracellular Signaling - A Hypothesis
    Cyril J Craven · 2015 · International Journal of Diabetes and Clinical Research
  18. β-Cell Regeneration Is Driven by Pancreatic Plasticity
    Adrián Holguín-Horcajo, Rocı́o Sancho, Meritxell Rovira · 2024 · Advances in anatomy, embryology and cell biology
  19. Incretin Mimetics Vildagliptin and Exenatide Improve Pedicle Skin Flap Survival in Rats.
    Л. М. Даниленко, Alla P. Tarasova, Mikhail V. Pokrovskiy, Konstantin S. Trunov, Yulia V. Stepenko, Elena Borisovna Artyushkova, Олег Сергеевич Гудырев · 2019 · Journal of World s Poultry Research
  20. Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2
    Matthew Wortham, Bastian Ramms, Chun Zeng, Jacqueline R. Benthuysen, Somesh Sai, Dennis P. Pollow, Fenfen Liu, Michael Schlichting, Austin R. Harrington, Bradley Liu et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis
    Jeongkyung Lee, Ruya Liu, Byung S. Kim, Yiqun Zhang, Feng Li, Rajaganapti Jagannathan, Ping Yang, Vinny Negi, Joseph Danvers, Eliana Melissa Perez-Garcia et al. · 2024 · eLife
  22. Transcriptome-wide N6-methyladenosine methylation dynamic profile in type 1 diabetes progression
    Duan Wu, Ziyi Peng, KUN YU YANG, Mengyuan Hu, Xuefeng Yu, Benping Zhang, Li Liu · 2025 · Epigenomics
  23. Prolactin: An Effective Partner for Anti-CD3 in Treating Type 1 Diabetes
    Xiangwei Xiao · 2015 · Endocrinology
  24. Incretin-Based Therapies: Revisiting Their Mode of Action
    Brian Thomas Layden, Barton L. Wicksteed, Franck Mauvais‐Jarvis · 2017 · Endocrinology
  25. Regenerative Medicine
    S.G. Davies, Peter D. Kennewell, Angela J. Russell, Laurence Silpa, Robert Westwood, Graham M. Wynne · 2016 · Elsevier eBooks
  26. A new shortened protocol to obtain islet-like cells from hESC-derived ductal cells
    Mehrdad Vakilian, Abdelkrim Hmadcha, Bernat Soria, Kamran Ghaedi · 2021 · In Vitro Cellular & Developmental Biology - Animal
  27. Effect of Herbal Medicine on Insulin Signaling Pathways and Insulin Resistance in Metabolic Dysfunction-associated Fatty Liver Disease: A Review
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  28. The regenerating gene (Reg) family genes in inflammatory bowel disease (IBD)
    Shin Takasawa, Tomoko Uchiyama, Maiko Takeda · 2025 · Exploration of Medicine
  29. Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially
    Sarah Akbib, Jordy Stichelmans, Geert M. Stangé, Zhidong Ling, Zerihun Assefa, Karine Hellemans · 2019 · PLoS ONE
  30. Strategies to promote beta-cell replication and regeneration
    Xiangwei Xiao · 2019 · Elsevier eBooks
  31. Induction of ß Cell Replication by Small Molecule-Mediated Menin Inhibition and Combined PKC Activation and TGF‑ß Inhibition as Revealed by A Refined Primary Culture Screening.
    Saghar Pahlavanneshan, Mehrdad Behmanesh, Yaser Tahamtani, Ensiyeh Hajizadeh‐Saffar, Mohsen Basiri, Hossein Baharvand · 2021 · PubMed Central
  32. Neue Ansätze zur Regeneration der insulinproduzierenden β-Zelle
    Elke Schlüssel, Heiko Lickert · 2022 · Die Diabetologie
  33. Studies of Rare Human Diseases Lead to Insights into Regulation of Human Beta-cell Proliferation
    MAUREEN A. GANNON · 2024 · Endocrinology
  34. Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis
    Jeongkyung Lee, Ruya Liu, Byung S. Kim, Yiqun Zhang, Feng Li, Rajaganapti Jagannathan, Ping Yang, Vinny Negi, Joseph Danvers, Eliana Melissa Perez-Garcia et al. · 2024 · eLife
  35. An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplant
    Rebecca A. Lee, Deeksha Gambhir, Vinh Q Nguyen, Xi‐Ping Huang, Yaohuan Zhang, Kaavian Shariati, Nicholas Yiv, Rebecca C. Schugar, Justin P. Annes, Bryan L. Roth et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Global research trends on diabetic islet regeneration (2012–2022): a ten-year bibliometric study
    Yulin Sun, Lingling Jia, Ying Wang, Rong Guo, Tingting Xi, Hua Jiang, Jiachao Xiong · 2024 · International Journal of Diabetes in Developing Countries
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  38. Insulinotropic and Beta-Cell Proliferative Effects of Unripe Artocarpus heterophyllus Extract Ameliorate Glucose Dysregulation in High-Fat-Fed Diet-Induced Obese Mice
    Prawej Ansari, Sara S. Islam, Asif Ali, Md. Samim R. Masud, Alexa D. Reberio, Joyeeta Tahseen Khan, J. M. A. Hannan, Peter R. Flatt, Yasser H.A. Abdel‐Wahab · 2025 · Diabetology
  39. Introduction to Free Radicals
    Biswajit Mukherjee, Alankar Mukherjee, Rima Chandra, Srijita Gope, Sefali Halder Hota, Sohini Chakraborty · 2025 · Springer eBooks
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    Lynne Cherchia, Scott E. Fraser, Stacey D. Finley, Falk Schneider · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  41. Enzymatically Crosslinked Chitosan–Hyaluronic Acid Layer-by-Layer Microcapsules with Controlled Permeability and Enhanced Stability for Cell Encapsulation
    Ririko Terada, Shinji Sakai · 2026 · Polymers
  42. eIF4A1 enhances p70S6K mRNA translation and promotes nuclear β-catenin levels to augment stemness and metastasis in gastric cancer cells
    Xiangyu Su, Yingming Zhu, Xuemin Song, Zhengcheng Yun, Yueqi He, Yiting Wu, Chanchan Gao · 2026 · Biochemical Pharmacology