Adipocyte metrnl antagonizes insulin resistance through PPARγ signaling
Li, Zhi-Yong, Song, Jie, Zheng, Si-Li, Fan, Mao-Bing, Guan, Yun-Feng, Qu, Yi, Xu, Jian, Wang, Pei +1 more·2015·Diabetes
Cited by (204)
Items 101–200 of 204
- Serum Metrnl is Decreased in Metabolic Dysfunction-Associated Fatty Liver Disease: A Case-Control StudyMei Liu, Xiangqian Gao, Yang Tian, Huiwei Li, Ziqi Yin, Lei Han, Lei Zhang · 2024 · Diabetes Metabolic Syndrome and Obesity
- Suksdorfin Promotes Adipocyte Differentiation and Improves Abnormalities in Glucose Metabolism via PPARγ ActivationMari Iwase, Takayuki Yamamoto, Kanako Nishimura, Haruya Takahashi, Shinsuke Mohri, Yongjia Li, Huei‐Fen Jheng, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim et al. · 2017 · Lipids
- The blooming intersection of subfatin and metabolic syndromeShenglei Huang, Lei Cao, Hongwei Cheng, Dongliang Li, Yi W. Li, Zhixian Wu · 2021 · Reviews in Cardiovascular Medicine
- Changes Induced by Aging and Long-Term Exercise and/or DHA Supplementation in Muscle of Obese Female MiceAlejandro Martínez-Gayo, Elisa Félix‐Soriano, Neira Sáinź, Pedro González‐Muniesa, María Jesús Moreno-Aliaga · 2022 · Nutrients
- Chronic vascular pathogenesis results in the reduced serum Metrnl levels in ischemic stroke patientsZhu‐Wei Miao, Nuo Wang, Wenjun Hu, Si‐Li Zheng, Dongsheng Wang, Fu-qiang Chang, Zhi Wang, Jia‐Sheng Tian, Xiaohui Dong, Tao Wu et al. · 2024 · Acta Pharmacologica Sinica
- IL-39 Reduces Proliferation and Promotes Apoptosis of Bladder Cancer by Altering the Activity of Cyclin E and FasHuaping Xiao, HAMZA ALISIC, BRANDON T. REIMAN, Zuliang Deng, ZIWEN ZHU, Nathan T. Givens, Qian Bai, ANDREW TAIT, Mark R. Wakefield, Yujiang Fang · 2021 · Anticancer Research
- Myokines as potential mediators of changes in glucose homeostasis and muscle mass after bariatric surgeryLaura Orioli, Jean‐Paul Thissen · 2025 · Frontiers in Endocrinology
- Acute/Chronic Responses of Combined Training on Serum Pro-thermogenic/Anti-inflammatory Inducers and Its Relation With Fed and Fasting State in Overweight Type 2 Diabetic IndividualsIvan Luiz Padilha Bonfante, Renata Garbellini Duft, Keryma Chaves da Silva Mateus, Joice Cristina dos Santos Trombeta, Enrico Antonio Rautenberg Finardi, Ana Paula Boito Ramkrapes, Diego Trevisan Brunelli, Marcelo A. Mori, Mara Patrícia Traina Chacon‐Mikahil, Licio Augusto Velloso et al. · 2022 · Frontiers in Physiology
- Hepatic Nampt Deficiency Aggravates Dyslipidemia and Fatty Liver in High Fat Diet Fed MiceDaoxin Wang, Sheng-li Qing, Zhu‐Wei Miao, Heng-Yu Luo, Jia‐Sheng Tian, Xiuping Zhang, Shu‐Na Wang, Tian-Guang Zhang, Chao‐Yu Miao · 2023 · Cells
- Unveiling the Effects of Interval Resistance Training and Chlorella Vulgaris Supplementation on Meteorin-like Protein and Oxidative Stress in Obese MenDelfan, Maryam, Radkia, Fatemeh, Juybari, Raheleh Amadeh, Daneshyar, Saeed, Willems, Mark ET, Saeidi, Ayoub, Hackney, Anthony C, Laher, Ismail, Zouhal, Hassane · 2024 · Current Developments in Nutrition
- Metrnl protects intestinal barrier function by regulating tight junctions via the IKKβ/IκBα/NFκB/MLCK/MLC signaling pathwayZhiyong Li, Heng-Yu Luo, Fei Xu, Yao Xu, Chunhui Ma, Sai-Long Zhang, Sheng Xu, Yuan-Yuan Ma, Nan Li, Chao‐Yu Miao · 2025 · Cell Death Discovery
- Maternal obesity and gestational diabetes decrease Metrnl concentrations in cord plasmaMartha Lappas · 2019 · The Journal of Maternal-Fetal & Neonatal Medicine
- Protective effects of METRNL overexpression against pathological cardiac remodelingCao Huang, Yiming Liao, Junmou Hong · 2024 · Gene
- The Function and Mechanism of Anti-Inflammatory Factor Metrnl Prevents the Progression of Inflammatory-Mediated Pathological Bone Osteolytic DiseasesNan Liu, Jinlei Dong, Lianxin Li, Dongsheng Zhou, Fanxiao Liu · 2024 · Journal of Inflammation Research
- Meteorin-like protein (Metrnl): a key exerkine in exercise-mediated cardiovascular healthHamid Alizadeh, Ahmad Parsaeifar, Roohollah Mohammadi Mirzaei · 2025 · Archives of Physiology and Biochemistry
- Meteorin-like levels are associated with active brown adipose tissue in early infancyCristina García-Beltrán, Artur Navarro‐Gascon, Abel López‐Bermejo, Tania Quesada‐López, Francis de Zegher, Lourdes Ibáñez, Francesc Villarroya · 2023 · Frontiers in Endocrinology
- Immunomodulation through Nutrition Should Be a Key Trend in Type 2 Diabetes TreatmentKatarzyna Napiórkowska-Baran, Paweł Treichel, Marta Czarnowska, Magdalena Drozd, Kinga Koperska, Agata Węglarz, Oskar Schmidt, Samira Darwish, Bartłomiej Szymczak, Zbigniew Bartuzi · 2024 · International Journal of Molecular Sciences
- Plasma interleukin-41 serves as a potential diagnostic biomarker for Kawasaki diseaseXiaohong Cai, Kan Li, Mingcai Li, Yanbo Lu, Junhua Wu, Haiyan Qiu, Yan Jun Li · 2023 · Microvascular Research
- Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetesAdem Yavuz, Mustafa Ata Aydin, Kader Uğur, Suna Aydın, Arzu Senol, Yakup Baykuş, Rulin Deniz, İbrahim Şahin, Mehmet Hanifi Yalçın, Berrin Gençer Tarakçı et al. · 2023 · Biotechnic & Histochemistry
- Association of Meteorin-Like Hormone with insulin resistance and body composition in healthy Iranian adultsHamid Alizadeh, Aliakbar Alizadeh · 2020 · Diabetes & Metabolic Syndrome Clinical Research & Reviews
- Impact of 8-week cold-and warm water swimming training combined with cinnamon consumption on serum METRNL, HDAC5, and insulin resistance levels in diabetic male ratsSeyed Morteza Tayebi, Saleh Motaghinasab, Rasoul Eslami, Somayeh Ahmadabadi, Aref Basereh, Iman Jamhiri · 2024 · Heliyon
- Effects of meteorin-like hormone on endocrine function of hypothalamo-hypophysial system and peripheral uncoupling proteins in ratsGüldeniz Şekerci, Yavuz Erden, Suat Tekin · 2022 · Molecular Biology Reports
- Low Levels of Metrnl are Linked to the Deterioration of Diabetic Kidney DiseaseJin Chen, Zhiyong Li, Fei Xu, Chaoqun Wang, Wenwen Li, Jin Lu, Chao‐Yu Miao · 2024 · Diabetes Metabolic Syndrome and Obesity
- Meteorin-like protein alleviates intervertebral disc degeneration by suppressing lipid accumulation in nucleus pulposus cells via PPARα-CPT1A activationZhengqi Huang, Ming Shi, Chao Zhang, Zhihuai Deng, Tianyu Qin, Jiajun Wu, Xiaohe Zhang, Weitao Han, Shuangxing Li, Bo Gao et al. · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- METRNL represses beta-to-alpha cell trans-differentiation to maintain beta cell function under diabetic metabolic stress in miceYüxia Zhou, Laying Hu, Ruijuan Zhuang, Lingyu Song, Xuebing Chang, Lu Liu, Yali Huang, Miao Zhang, Jing Zheng, Xiaohui Xu et al. · 2025 · Diabetologia
- Homotherapy for heteropathy: Interleukin‐41 and its biological functionsRunfeng Shi, Meixin He, Yongzheng Peng, Xia Xu · 2024 · Immunology
- Meteorin-like Protein and Zonulin in Polycystic Ovary Syndrome: Exploring Associations with Obesity, Metabolic Parameters, and InflammationPlamena Kabakchieva, Antoaneta Gateva, Tsvetelina Veselinova Velikova, Tsvetoslav Georgiev, Kyosuke Yamanishi, Haruki Okamura, Zdravko Asenov Kamenov · 2024 · Biomedicines
- Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activation during hepatic fibrosisYüxia Zhou, Guifang Wang, Lingling Liu, Lingyu Song, Laying Hu, Lu Liu, Lifen Xu, Tuanlao Wang, Lirong Liu, Yuanyuan Wang et al. · 2025 · Cell Death and Disease
- The hMetrnl-PLGA-PEG-PLGA Hydrogel Facilitates Skin Wound Healing Through Dual Regulation on eNOS Activity and StabilityHuanyu Zhao, Jie-Bing Jiang, Yu Chen, Chao‐Yu Miao · 2025 · Pharmaceuticals
- Transcriptional Control of Subcutaneous Adipose Tissue by the Transcription Factor CTCF Modulates Heterogeneity in Fat Distribution in WomenEdina Erdős, Katalin D. Sandor, Crystal L. Young, László Halász, Steven R. Smith, Timothy F. Osborne, Adeline Divoux · 2023 · Cells
- Meteorin-β: A Novel Biomarker and Therapeutic Target on Its Way to the Regulation of Human DiseasesBei Wang, Li Xiao, Xun Gao · 2025 · International Journal of Molecular Sciences
- Distribution of Nicotinamide Mononucleotide after Intravenous Injection in Normal and Ischemic Stroke MiceChao‐Yu Miao, Si‐Li Zheng, Dongsheng Wang, Xin Wen Dong, Yun‐Feng Guan, Qi Qi, Wenjun Hu, Chen Hong, Chuan Zhang · 2022 · Current Pharmaceutical Biotechnology
- Association between Metrnl and carotid atherosclerosis in patients with type 2 diabetes mellitusChunmei Li, Qiongzhu Huang, Yanqian Zhuang, Pin Chen, Yiyang Lin · 2025 · Frontiers in Endocrinology
- Skeletal muscle growth to combat diabetes and obesity: the potential role of muscle‐secreted factorsMitchell J. Sammut, Benjamin R. Thorne, C.W. James Melling · 2025 · Obesity
- Meteorin‐Like Protein (Metrnl): An Exercise‐Induced Myokine With Therapeutic Potential in Metabolic and Inflammatory DisordersLijun Zhou, Huanyu Long, Hamid Alizadeh · 2025 · Obesity Reviews
- Serum interleukin-38 and -41 levels as candidate biomarkers in male infertilityChunhao Rong, Linjie Weng, Mingcai Li, Liming Zhou, Yan Li · 2023 · Immunology Letters
- Association of serum Metrnl levels and high-density lipoprotein cholesterol in patients with type 2 diabetes mellitus: a cross-sectional studyChenxia Zhou, Juli Zeng, Xiangyu Gao, Da Chen, Qiu‐Gen Zhu, Bo Feng, Jun Ho Song · 2024 · PeerJ
- Potential clinical value of serum interleukin-41 levels in patients with acute goutYinxin Zhou, Shanjun Shi, Sicen Meng, Hui Zhao, Xiudi Wu, Mingcai Li, Yan Li · 2023 · International Immunopharmacology
- Inhibition of macrophage extracellular traps by Metrnl/IL-41 suppresses airway remodeling in asthmaKang-ni Feng, Jiemei Cen, Chunyan He, Xiaoling Zou, Hailing Yang, Yusen Lin, Hongtao Li, Tiantuo Zhang · 2025 · Biochemical Pharmacology
- Emerging Therapeutic and Inflammation Biomarkers: The Role of Meteorin-Like (Metrnl) and Follistatin-Like 1 (FSTL1) in Inflammatory DiseasesTsvetelina Veselinova Velikova, Konstantina Bakopoulou, Milena Gulinac, Evelina Manova, Hristo Yankov Valkov, Dimitrina Miteva, Russka Shumnalieva · 2025 · International Journal of Molecular Sciences
- Investigation of IL-35 and IL-39, New Members of the IL-12 Family, in Different Clinical Presentations of BrucellosisPınar Hız Ellergezen, Muhammed Ali Kızmaz, Abdurrahman Şimşek, Nesrin Demir, Eren Çağan, Salih Haldun Bal, Halis Akalın, Haluk Barbaros Oral, Ferah Budak · 2023 · Immunological Investigations
- Low serum Metrnl levels are associated with increased risk of sarcopenia in the older adultsZhiyue Wang, Yimin Li, Jian-Jun Yan, Quan Wang, Can Zhao, Xiang Lu, Zheng‐Kai Shen, Jinshui Xu, Wei Qiang Gao · 2024 · European Geriatric Medicine
- Metrnl and Cardiomyopathies: From Molecular Mechanisms to Therapeutic InsightsMiaomiao Xu, Xiaoguang Liu, Liming Lu, Zhaowei Li · 2025 · Journal of Cellular and Molecular Medicine
- The Effects of Meteorin‐Like Protein on Diabetic Neuropathy: In Vivo and In Vitro Model StudiesFurkan Yüksel, Asli Taslidere, Mete Özcan, Çiğdem Samancı Tekin, Suat Tekin · 2025 · Journal of Biochemical and Molecular Toxicology
- Subfatin concentration decreases in acute coronary syndromeMustafa Yilmaz, Mehmet Cagri Goktekin, Nevin İlhan · 2022 · Biochemia Medica
- Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in miceTomomi Masuya, Miyako Suzuki, Junko Tsujimura, Shinsaku Kanamori, Yuki Miyasaka, Tamio Ohno, Atsushi Murai, Fumihiko Horio, Misato Kobayashi · 2020 · PLoS ONE
- Slfn2 mutation‐induced loss of T‐cell quiescence leads to elevated de novo sterol synthesisIbrahim Omar, Oren Rom, Michael Aviram, Leonor Cohen‐Daniel, Abraham K. Gebre, John S. Parks, Michael Berger · 2017 · Immunology
- Adipose thermogenic mechanisms by cold, exercise and intermittent fasting: Similarities, disparities and the application in treatmentLin-Shan Chen, Longhua Liu · 2024 · Clinical Nutrition
- Interleukin-41: a novel serum marker for the diagnosis of alpha-fetoprotein-negative hepatocellular carcinomaYazhao Li, Haoyu Wang, Danfeng Ren, Jingyu Li, Zihan Mu, Chaoyi Li, Yongchao He, Jiayi Zhang, Rui Fan, Jiayuan Yin et al. · 2024 · Frontiers in Oncology
- METRNL mitigates oxidative stress and inflammatory drawbacks in ovalbumin/lipopolysaccharide-induced allergic airway diseases via the IKK/IκB/NF-κB signaling pathwaySuzan A Khodir, Anwaar M. Shaban, Eman M. Sweed, Noha M Abd El-aziz, Basma Abdelnaby Mostafa, Asmaa A. Abdel Latif, Mai M El-Kalshy, Eman Ibrahim Elgizawy · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Meteorin-like/Metrnl: A pleiotropic cytokine implicated in metabolic, inflammatory and malignant disordersJinlian Li, Pei Ye, Jingli Si, Guangda Xiang · 2025 · Cytokine & Growth Factor Reviews
- Metrnl/Meteorin-like/IL-41 Alleviates Rheumatoid Arthritis Via PPARγ-Mediated Suppression of Inflammation, Angiogenesis, and Bone DestructionTao Sun, Liping Xia, Yuxuan Li, Min Zhao, Zhuoqi Li, Hui Shen · 2026 · Inflammation
- Cellular crosstalk in doxorubicin-induced cardiotoxicity: underlying mechanisms and therapeutic strategiesJinwen Wei, Qianru Zhao, Changxu Lu, Can Gao, Zhongyi Mu, Dan Dong, Mingli Sun · 2026 · Biochemical Pharmacology
- Endothelial versus global METRNL reveals importance of endothelial METRNL against atherosclerosis via mitochondrial homeostasisDao-Xin Wang, Pin Wang, Zhu‐Wei Miao, Shu-Na Wang, Si-Li Zheng, Xue-Lian Wang, Jiaxin Li, Zhi-Yong Li, Yu Chen, Tian-Guang Zhang et al. · 2026 · Pharmacological Research
- The Plasma Levels of Protein Adiponectin (AdipoQ) and Meteorin-Like (Metrnl) in Newly Diagnosed Type 2 Diabetes MellitusLan Thi Phuong Dam, Thinh Tran Huy, Thuan Huynh Quang · 2024 · Diabetes Metabolic Syndrome and Obesity
- Exploration of meteorin-like peptide (metrnl) predictors in type 2 diabetic patients: the potential role of irisin, and other biochemical parametersYaser Khajebishak, Amir Hossein Faghfouri, Ali Soleimani, Sadra Madani, Laleh Payahoo · 2022 · Hormone Molecular Biology and Clinical Investigation
- Effects of circuit resistance training on serum myokine METRNL and cardiometabolic health markers in overweight participants: A 6 week intervention studyAlizadeh, Hamid, Safarzade, Alireza · 2025 · Sport Sciences for Health
- Metrnl in health and disease: tissue-specific actions and signaling networksRan Zhao, Yue Qi, Pan Li, Zhe Zhang, Yiyang Chen, Xiaopeng Wu, Wei Wang, Xiaoqing Guo, Huadong Zhao, Yang Yang et al. · 2026 · APOPTOSIS
- Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanismTian‐Ying Xu, Jing-Xin Zhao, Ming-Yao Chen, Zhu‐Wei Miao, Zhiyong Li, Yong-Qing Chang, Yu-Sheng Wang, Chao‐Yu Miao · 2025 · Journal of Intensive Care
- Meteorin-Like Protein Levels Decrease in Patients With Acute Ischaemic Strokeİbrahim Halil Yasak, Mustafa Yılmaz, Mehmet Çağrı Göktekin, Ramazan Giden, İsmail Koyuncu · 2022 · Cureus
- Carvacrol protects rat liver exposed to formaldehyde by regulating oxidative stress, and asprosin and subfatin hormonesE. Emre, Murat Ögetürk, Süleyman Aydın, Tuncay Kuloğlu, Feyza Aksu, Ahmet Kavaklı · 2023 · Biotechnic & Histochemistry
- Elevation of Metrnβ and Its Association with Disease Activity in Systemic Lupus ErythematosusChen Zhang, Shijie Cai, Ying Li, Xiaoyan Xu, Yonghui Liu, Huaiyu Qiao, Chun Kwok Wong, Guoqiu Wu, Hui Jin, Xun Gao · 2023 · International Journal of Molecular Sciences
- Role of asprosin and meteorin-like peptide in progression of actinic keratosis to squamous cell carcinomaEsma İnan Yüksel, Demet Çiçek, Betül Demir, Nevin Kocaman, İlknur Çalık, Tuncay Kuloğlu · 2024 · Biotechnic & Histochemistry
- Elevated serum Meteorin-like levels in patients with hyperthyroidismXiaohui Wen, Xiaoyu Ding, Xiaona Chang, Jiaxuan Wang, Qiu Wang, Jia Liu, Guang Wang · 2022 · BMC Endocrine Disorders
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- Low Circulating Metrnl Levels are Linked to Higher Abdominal Fat in Elderly T2DM Patients: A Gender-Based StudyJiangli Pei, Dan Zhao, Xinhua Ye, Yunfeng Du · 2025 · Diabetes Metabolic Syndrome and Obesity
- The emerging role of interleukin-41: a novel biomarker and therapeutic target in inflammation and immune-related diseasesZhi Li, Mingcai Li, Yan Li · 2026 · Cytokine
- Meteorin-like ameliorates acute bacterial lung infection by enhancing neutrophil functionHao Ding, Jiayu Liu, Yi Gong, Kehan Wang, Renlin Yu, Yi Liu, Xiaofei Lai, Ju Cao · 2026 · American Journal of Respiratory Cell and Molecular Biology
- Relationship between meteorin-like peptide (Metrnl) serum levels and inflammatory cytokines, oxidative stress biomarkers and body composition parameters in type 2 diabetes patientsYaser Khajebishak, Sadra Madani, Amir Hossein Faghfouri, Ali Soleimani, Sara Ilaei, Said Peyrovi, Laleh Payahoo · 2022 · Nutrition & Food Science
- Novel single nucleotide polymorphism (rs1600485907) of IL-41 gene associated with systemic lupus erythematousReema Mohammed Abed, Laith Ahmed Yaaqoob · 2023 · Asia-Pacific Journal of Molecular Biology and Biotechnology
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- Metrnl Reduces Thrombosis and Acute Myocardial Injury Through Inhibition of Platelet Activation via CD36 Receptor DegradationZhu‐Wei Miao, Can-Xin Chen, Pin Wang, Si-Li Zheng, Jie-Bing Jiang, Wen-Jun Hu, Xiaoyan Zhu, Bin Lu, Liming Chen, Liang Hu et al. · 2026 · Circulation
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- Serum Metrnl Levels in Patients with Sepsis-Induced Myocardial Injury and Their Prognostic SignificanceJiao Chen, Jinfeng Lin, Wei Zhao, Xiang Xue, Xiang Lü, Chongxiu Sun · 2025 · Research Square
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- Metrnl in mitigating radiation enteritis via label-retaining cells protection by modulating the c-KIT-WNT pathwaySailong Zhang, Simin Chen, Bingjie Guo, Qisheng Ling, Shuling Wang, Zhuwei Miao, Zhi Wang, Yuchen Wei, Sili Zheng, Zhiyong Li et al. · 2026 · Acta Pharmaceutica Sinica B
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