Vinegar ingestion at bedtime moderates waking glucose concentrations in adults with well-controlled type 2 diabetes
Open accessAbstract
iven the importance of maintaining acceptable blood glucose concentrations, there is much interest in identifying foods and diet patterns that will help individuals with diabetes manage their condition.Based on previous data indicating that vinegar ingestion at mealtime reduces postprandial glycemia (1-4), the aim of this pilot study was to examine whether vinegar ingestion at bedtime reduces the next-morning fasting glucose concentration in individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS-Four men and seven women (aged 40 -72 years) diagnosed with type 2 diabetes (by a physician) who were not taking insulin completed the study.Participants provided a clinically determined A1C reading from a recent (Ͻ2 months) blood analysis.All participants gave written informed consent, and the study was approved by the institutional review board at Arizona State University.Participants maintained 24-h diet records for 3 days and measured fasting glucose at 0700 h for 3 consecutive days with a calibrated glucometer before the start of the study.Participants were instructed to continue usual prescription medication use during the study.Utilizing a randomized crossover design with a 3-to 5-day washout period between treatments, participants followed a standardized meal plan for 2 days, consuming either 2 Tbsp apple cider vinegar or water at bedtime with 1 oz cheese (8 g protein,
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Vinegar intake at bedtime was associated with lower fasting glycemia by decreasing the rates of hepatic gluconeogenesis and improving insulin secretion in subjects with T2DM.
“Vinegar intake at bedtime was associated with lower fasting glycemia by decreasing the rates of hepatic gluconeogenesis and improving insulin secretion in subjects with T2DM [401].”
From Effects of diet, lifestyle, Chrononutrition and alternative dietary interventions on postprandial Glycemia and insulin resistance (2022) · cites this paper as [401]
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- Authors
- White, A. M., & Johnston, C. S.
- Affiliations
- Arizona State University (US)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2007-11-01
- Volume
- 30
- Issue
- 11
- Pages
- 2814-2815
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W1989243836
- Cited by
- 58
- References
- 21
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 4 · 2021: 7 · 2020: 6 · 2019: 7 · 2018: 2 · 2017: 1 · 2016: 8 · 2015: 4 · 2014: 3 · 2013: 2
- FWCI
- 2.19
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Keywords
- apple cider vinegar, type 2 diabetes, fasting blood glucose, glycemic control, postprandial blood glucose, dietary intervention
- MeSH terms
- Adult, Aged, Blood Glucose, Diabetes Mellitus, Type 2, Diet, Diabetic, Drug Administration Schedule, Female, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Male, Middle Aged, Diet Records, Acetic Acid
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