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Cited by 476

The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.

Cardiac Autonomic Neuropathy in Diabetes

Open access
Pop-Busui, Rodica·2010·Diabetes Care

Abstract

his review covers the epidemiology, pathophysiology, clinical presentation, and diagnosis of cardiac autonomic neuropathy (CAN) in diabetes and discusses current evidence on approaches to prevention and treatment of CAN.CASE PRESENTATION -A 2 6year-old woman with "brittle" type 1 diabetes and severe CAN experienced sudden cardiac death.She had a 16-year history of poor diabetes control presenting with wide blood glucose fluctuations, recurrent episodes of severe hypoglycemia, and hypoglycemia unawareness.Over time she developed persistent orthostatic hypotension with daily falls in systolic blood pressure ranging from 30 -60 mmHg.These episodes had significant impact on her daily activities and required intermittent therapy with the ␣-1 agonist midodrine.Other complications included severe gastroparesis, refractory diarrhea, and painful diabetic peripheral neuropathy.Her last clinical examination revealed resting tachycardia with a fixed rate of 115 bpm, supine blood pressure of 110/78 mmHg, which dropped to 70/48 mmHg while standing, symmetrical absent pinprick and temperature discrimination in stocking distribution, and left Charcot joint.Her last pertinent laboratory findings were A1C 8.7%, creatinine 1.9 mg/dl, microalbumin/creatinine 496 mg/g, and hemoglobin 10.8 g/dl.•

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Metadata

Authors
Pop-Busui, R.
Venue
Diabetes Care
Published
2010-02-01
Volume
33
Issue
2
Pages
434-441
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
OpenAlex
W1999716853
Cited by
476
References
65
FWCI
25.77
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Cardiac Autonomic Neuropathy in Diabetes. https://app.cochat.ai/papers/10.2337/dc09-1294
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Pop-Busui, R. (2010). Cardiac Autonomic Neuropathy in Diabetes. Diabetes Care. https://doi.org/10.2337/dc09-1294

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