Increased Circulating Levels of Betatrophin in Newly Diagnosed Type 2 Diabetic Patients

Hu, Hao, Sun, Wenjun, Yu, Shuqin, Hong, Xiafei, Qian, Weiyun, Tang, Bingqian, Wang, Dong, Yang, Ling, Wang, Jifang, Mao, Caoming, Zhou, Libin, Yuan, Guoyue·2014·Diabetes Care

DOI 10.2337/dc14-0602

Cited by (169)

Items 101–169 of 169

The Correlation Between Circulating Betatrophin and Insulin Resistance in General Population: A Meta-Analysis
Jinling Xu, Yanyan Lin, Hui Ren Zhou, Linshuang Zhao, Guangda Xiang · 2017 · Hormone and Metabolic Research
Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
EnXu Li, Masanori Nakata, Atsumi Shinozaki, Yifei K. Yang, Boyang Zhang, Toshihiko Yada · 2016 · Endocrine Journal
Increased serum levels of betatrophin in pancreatic cancer-associated diabetes
Hendra Susanto, Ta-Yu Liu, Chang-Chiang Chen, Jerry Dwi Trijoyo Purnomo, Shu-Fan Chen, Chih-Hong Wang · 2016 · Oncotarget
Circulating betatrophin in relation to metabolic, inflammatory parameters, and oxidative stress in patients with type 2 diabetes mellitus
Alan Bapeer Hassan, Sherwan Ferman Salih, Israa Issa Hassan, Farsat Saeed Saadi, Deldar Morad Abdulah, Idris Haji Ahmed, Sherzad Majeed Taher, Bland Bayar Khaleel · 2018 · Diabetes & Metabolic Syndrome Clinical Research & Reviews
Serum Betatrophin Concentrations and the Risk of Incident Diabetes: A Nested Case-Control Study from Chungju Metabolic Disease Cohort
Seung‐Hwan Lee, Marie Rhee, Hyuk‐Sang Kwon, Yong‐Moon Park, Kun‐Ho Yoon · 2018 · Diabetes & Metabolism Journal
Brain-acting hepatokines: its impact on energy balance and metabolism
Lucía Giovanini, Nahuel Ezequiel Wanionok, Mario Perelló, María Paula Cornejo · 2025 · Frontiers in Neuroscience
Increased circulating full-length betatrophin levels in drug-naïve metabolic syndrome
Dan Liu, Sheyu Li, He He, Chuan Yu, Xiaodan Li, Libo Liang, Yi Chen, Jianwei Li, Jianshu Li, Xin Sun et al. · 2017 · Oncotarget
Circulating ANGPTL8 levels and risk of kidney function decline: Results from the 4C Study
Huajie Zou, Yongping Xu, Xiaoyu Meng, Danpei Li, Xi Chen, Tingting Du, Yan Yang, Yong Chen, Shiying Shao, Gang Yuan et al. · 2021 · Cardiovascular Diabetology
Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes
Adem Yavuz, Mustafa Ata Aydin, Kader Uğur, Suna Aydın, Arzu Senol, Yakup Baykuş, Rulin Deniz, İbrahim Şahin, Mehmet Hanifi Yalçın, Berrin Gençer Tarakçı et al. · 2023 · Biotechnic & Histochemistry
Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus–A Co-expression Network Based Analysis
Amnah Siddiqa, Elisa Cirillo, Samar Hayat Khan Tareen, Amjad Ali, Martina Kutmon, Lars Eijssen, Jamil Ahmad, Chris T. Evelo, Susan L. Coort · 2018 · Frontiers in Physiology
Evaluation of second-trimester maternal serum betatrophin levels and lipid and carbohydrate metabolism parameters in patients with gestational diabetes mellitus
Funda Gülcü Bulmuş, Rauf Melekoğlu, Mehmet Ferit Gürsu, Helin Bağcı, Ebru Çelik Kavak, Alpaslan Akyol · 2020 · Journal of Turkish Society of Obstetric and Gynecology
ANGPTL8 Gene Polymorphism rs2278426 Is Related to Carotid Intima–Media Thickness in T2DM
Chang Yue Guo, Li Zhao, Yi Ding, Zhicong Zhao, Chenxi Wang, Lian Li, Zhensheng Cai, Yanyan Li, Hong Xia, Zhuan-Zhuan Zhu et al. · 2020 · Diabetes Metabolic Syndrome and Obesity
Serum betatrophin levels are reduced in patients with full-blown polycystic ovary syndrome
Filiz Ekşi Haydardedeoğlu, Gülay Şimşek Bağır, Bülent Haydardedeoğlu, Emre Bozkırlı, Okan Bakıner, Kerem Metin, Melek Eda Ertörer · 2018 · Gynecological Endocrinology
Association of serum angiopoietin-like protein 2 with elevated risk of cardiovascular diseases in subjects with type 2 diabetes
Dalia H. El-Lebedy · 2019 · Journal of Diabetes and its Complications
The effect of 4-week endurance training on serum levels of irisin and betatrophin in streptozotocin- induced diabetic rats
Hamid Reza Sadeghipour, Golan Yeganeh, Abdossaleh Zar, Mohsen Salesi, Samad Akbarzadeh, Marco Bernardi · 2020 · Archives of Physiology and Biochemistry
Adolescent obesity and ANGPTL8: correlations with high sensitivity C-reactive protein, leptin, and chemerin
Maha M. Hammad, Arshad Mohamed Channanath, Mohamed Abu‐Farha, Abdur Rahman, Irina Al Khairi, Preethi Cherian, Tahani Alramah, Nada Alam-Eldin, Fahd Al‐Mulla, Thangavel Alphonse Thanaraj et al. · 2023 · Frontiers in Endocrinology
Decreased circulating levels of ANGPTL8 in Graves’ disease patients
Haoxiang Li, Mengjiao Xu, Li Zhao, Hong Xia, Yanyan Li, Xiafei Hong, Xia Deng, Jing Yuan, Yi Ding, Chang Yue Guo et al. · 2019 · HORMONES
Levels of betatrophin decrease during pregnancy despite increased insulin resistance, beta-cell function and triglyceride levels
Anna Zielińska, Rafał Maciulewski, Katarzyna Siewko, Anna Popławska‐Kita, Danuta Lipińska, Gabryela Kozłowska, Magdalena Górska, Małgorzata Szelachowska · 2016 · Diabetes & Metabolism
Cloning, Expression, Purification and CD Analysis of Recombinant Human Betatrophin.
Samaneh Gholami, Nematollah Gheibi, Reza Falak, Koorosh Goodarzvand Chegini · 2018 · Europe PMC (PubMed Central)
ANGPTL8 in cardio-metabolic diseases
Xin Su, Ye Cheng, Bin Wang · 2021 · Clinica Chimica Acta
Betatrophin Levels Are Related to the Early Histological Findings in Nonalcoholic Fatty Liver Disease
Alper Sönmez, Teoman Doğru, Cemal Nuri Erçin, Halil Genç, Gürkan Çelebi, Hasan Gürel, Serkan Tapan, Ali Fuat Çiçek, Cem Barçın, Cem Haymana et al. · 2021 · Metabolites
Plasma Betatrophin Levels and Carotid Atherosclerosis
Hanako Niki, Yoshimi Kishimoto, Emi Saita, Reiko Ohmori, Kazuo N. Kondo, Yukihiko Momiyama · 2019 · Disease Markers
ANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells
Fangfang Xu, Nan Wang, Gangqiang Li, Dandan Tian, Xiaoyang Shi · 2021 · Diabetes Metabolic Syndrome and Obesity
Effect of physical activity in a weight loss program on circulating total ANGPTL8 concentrations in northern Americans with obesity: A prospective randomized controlled trial
Chia‐Po Fu, Elizabeth A. Oczypok, Hira Ali, James P. DeLany, Valerie L. Reeves, Ruey‐Feng Chang, Erin E. Kershaw · 2022 · Nutrition Metabolism and Cardiovascular Diseases
Plasma Betatrophin Levels of Subjects Classified with Normal, Impaired, and Diabetic Glucose Tolerance, and Subjects with Impaired Fasting Glucose
Sibel Özyazgan, Burak Önal, Eda Merve Kurtuluş, Hafize Uzun, Gökhan Akkan, Dildar Konukoğlu · 2017 · Hormone and Metabolic Research
Serum Betatrophin Levels and Clinical Features in Patients With Poorly Controlled Type 2 Diabetes
Kohzo Takebayashi, Kenji Hara, Tomoko Terasawa, Rika Naruse, Mariko Suetsugu, Takafumi Tsuchiya, Toshihiko Inukai · 2017 · Journal of Clinical Medicine Research
Association of Circulating ANGPTL8 Levels With Renal Dysfunction: A Case-Control Study
Xiaoyu Meng, Huajie Zou, Danpei Li, Peng Yu, Li Huang, Jianhua Zhang, Wenjun Li, Xuefeng Yu · 2021 · Frontiers in Public Health
Plasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion
Mohamed Abu‐Farha, Mariam Alatrach, Jehad Ahmed Abubaker, Irina Al‐Khairi, Preethi Cherian, Krisitn Agyin, Siham Abdelgani, Luke Norton, John Adams, Dalal Alsaeed et al. · 2023 · Diabetes/Metabolism Research and Reviews
Plasma and aqueous levels of subfatin, preptin and betatrophin in patients with diabetic retinopathy
Sabiha Güngör Kobat, Fatih Cem Gül, Fatih Çelik, Seda Liman Uzun, Mehmet Ali Kobat, Ramazan Fazıl Akkoç, Süleyman Aydın · 2023 · BMC Ophthalmology
Association Between Plasma Levels of ANGPTL3, 4, 8 and the Most Common Additional Cardiovascular Risk Factors in Patients with Hypertension
Fangfang Xu, Lijun Shen, Yong‐Guang Yang, Limin Kong, Wufan Zu, Dandan Tian, Cao Xuanchao, Gairong Huang · 2023 · Diabetes Metabolic Syndrome and Obesity
Histology and molecular biology studies on the expression and localization of angiopoietin‑like protein 8 in human tissues
Naohiko Akimoto, Ryuichi Wada, Katsuhiko Iwakiri, Zenya Naito · 2019 · Biomedical Reports
Dyslipidemia and ANGPTL8 evaluation in young females with Type 1 diabetes mellitus
Walaa M. Mohammedsaeed, Dalal Nasser Binjawhar · 2024 · Endocrine
Insulin resistance and adaptation of pancreatic beta cells during pregnancy
Anna Zielińska-Maciulewska, Adam Jacek Kretowski, Małgorzata Szelachowska · 2018 · Clinical Diabetology
The Effect of Four Weeks of Long-Term Endurance Training with and Without Propolis Supplementation on Serum Levels of Betatrophin/ANGPTL8 in Male Athletes
Farzaneh Rashvand, Khadijeh Irandoust, Morteza Taheri, Saeideh Gholamzadeh Khoei, Nematollah Gheibi · 2022 · Asian Journal of Sports Medicine
Lipasin, a biomarker of diabetic retinopathy
Chen Fang, Yun Huang, Heming Guo, Yan Gao, Xiaoyan Ji, Ji Hu · 2016 · Diabetes Research and Clinical Practice
Maternal and cord blood betatrophin (angiopoietin‐like protein 8) in pregnant women with gestational diabetes and normoglycemic controls: A systematic review, meta‐analysis, and meta‐regression
Faustino Ramón Pérez-López, Junhua Yuan, Manuel Sánchez Prieto, María Teresa López-Baena, Gonzalo R. Pérez‐Roncero, Seshadri Reddy Varikasuvu · 2023 · Diabetes/Metabolism Research and Reviews
New insights into ANGPTL8 in modulating the development of cardio-metabolic disorder diseases
Xin Su, Guoming Zhang, Ye Cheng, Bin Wang · 2021 · Molecular Biology Reports
Association between circulating betatrophin levels and T2DM: a meta-analysis
Yuquan ZHAN · 2024 · Minerva Endocrinology
Serum betatrophin levels and fatty acid profile in gestational diabetes mellitus: Correlation with insulin resistance
Shyamaraja T. Udupa, Arnadi Ramachandrayya Shivashankara, Suchetha Kumari N., Shilpa Sharathraj Shetty, Prema D’Cunha · 2022 · Biomedicine
Alterations in serum concentrations of visfatin and betatrophin in dogs with hypothyroidism
Michal Mazaki‐Tovi, Omer Shachar, Tzachi Even Zur · 2023 · Journal of Veterinary Internal Medicine
Circulating angiopoietin-like protein 8 (ANGPTL8) and steatotic liver disease related to metabolic dysfunction: an updated systematic review and meta-analysis
Farah Abdelhameed, Lukasz Lagojda, Chris Kite, Alexander Dallaway, Attia Mustafa, Nwe Ni Than, Eva N. Kassi, Harpal Singh Randeva, Ioannis Kyrou · 2025 · Frontiers in Endocrinology
Protein-Based Biomaterial Marker in Metabolic Syndrome and Colorectal Cancer: A Preliminary Clinical Study of Betatrophin Expression in Javanese Ethnic
Hendra Susanto, Ahmad Taufiq, Dwi Inne Listyorini, Adeodatus Yuda Handaya, Melati Putri Pertiwi · 2019 · IOP Conference Series Materials Science and Engineering
Circulating Betatrophin and Hepatocyte Growth Factor in Type 2 Diabetic Patients: Their Relationship With Disease Prognosis
Abdulrahman Abdulwahab Alduraywish · 2017 · Journal of Endocrinology and Metabolism
L’internista ospedaliero nella gestione del paziente diabetico complesso
Guest Editors L. Magnani, Giampietro Beltramello, D. Brancato, Andrea Fontanella, Roberto Nardi · 2018 · Italian Journal of Medicine
Correlation of serum betatrophin levels with disease severity and the emergence of insulin resistance in cirrhotic patients
Mohamed Magdy Salama, Walaa Ahmed Yousry Kabiel, Silvia Shoukry Hana, Ghada Abdelrahman Mohamed · 2020 · Egyptian Liver Journal
Targeted Metabolomics Analysis of Individuals Carrying the ANGPTL8 R59W Variant
Mohamed Abu‐Farha, Shibu Joseph, Anwar Mohammad, Arshad Mohamed Channanath, Ibrahim Taher, Fahd Al‐Mulla, Muhammad Hussain Mujammami, Thangavel Alphonse Thanaraj, Jehad Ahmed Abubaker, Anas M. Abdel Rahman · 2023 · Metabolites
Residual beta-cell function in children with type 1 diabetes after a partial remission phase – a possible relation between C-peptide and betatrophin
Emilia Odyjewska, Monika Kupińska, Milena Jamiołkowska‐Sztabkowska, Artur Tadeusz Bossowski, Barbara Głowińska‐Olszewska · 2025 · Frontiers in Endocrinology
Betatrophin is correlated with glucagon and insulin release rather than insulin resistance marker in type 2 diabetes mellitus Iraqi women
Athir Kadhim Mohammed, Faris Abdul Kareem Khazaal · 2016 · International Journal of Research in Medical Sciences
RUTIN RESTORE BIOCHEMICAL CHANGES, OXIDATIVE STRESS AND BETATROPHIN LEVEL IN STZ-INDUCED DIABETIC RATS
Al‐Shimaa M. Abas, AHMED F. EL-FARAFG, NEHAL W. ABDALLA · 2019 · International Journal of Current Pharmaceutical Research
Study of Serum Betatrophin Level in The Patients of Type 2 Diabetes Mellitus
Aliaa H. El-Ghandour, Aml S. El-Bendary, Abeer Shahba, Ghada A. Soliman · 2019 · The Egyptian Journal of Hospital Medicine
The ANGPTL8 Levels as An Important a Biochemical Markers for The Women with T2DM
Manal F. Al-Khakani, Aws Safaa Fadhel · 2022 · Journal of Pharmaceutical Negative Results
Impact of Liver Cirrhosis on the Occurrence of Diabetes Mellitus and Glucose Intolerance among Liver Cirrhosis Patients in European Gaza Hospital: A Retroactive Study
2023 · Journal of Gastroenterology & Digestive Systems
The minor allele of ANGPTL8 rs2278426 has a protective effect against CAD in T2DM patients
Aslihan Gizem Bilgin, Berkay Ekici, A.S. Ozuynuk, Aycan Fahri Erkan, Neslihan Çoban · 2024 · Gene
Biomarkers of Insulin Resistance
Kimberly A. Cox‐York, Rocio I. Pereira · 2019 · Contemporary Endocrinology
Betatrophin is downregulated in pregnant women with a history of RYGB operation and a high risk of postprandial hypoglycaemia
Michael Leutner, Caspar Matzhold, Luise Bellach, Carola Deischinger, Stefan Thurner A, Peter Klimek, Alexandra Kautzky‐Willer · 2020 · Scientific Reports
Betatrophin in nonalcoholic fatty liver disease
Hasan Gürel, Teoman Doğru · 2016 · European Journal of Gastroenterology & Hepatology
Wyższe stężenie betatrofiny u pacjentów z noworozpoznaną cukrzycą
Rafał Maciulewski, Anna Zielińska-Maciulewska, Katarzyna Siewko, Gabryela Kozłowska, Danuta Lipińska, Anna Justyna Milewska, Maria Górska, Adam Jacek Kretowski, Małgorzata Szelachowska · 2019 · Clinical Diabetology
A Short Review on ANGPTL-8 as an Important Regulator in Diabetes
Maryam Esfahani, Mohammad Taghi Goodarzi · 2019 · Avicenna Journal of Medical Biochemistry
Assessment of Serum Level of Betatrophien in Acne Vulgaris Patient
F.M. Eleswy, Doaa M. Elhabak, R.A. Khashba, E.E. Zaky · 2020 · Benha Journal of Applied Sciences
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An Analysis of Circulating Betatrophin Levels in Relation with Type1 and Type2 Diabetes Mellitu Running Title: Betatrophin and Diabetes
Esma Altunoğlu, Füsun Erdenen, Aydın Seda, Koro Atakan, Uzun Hafize · 2021 · Annals of Endocrinology and Metabolism
Molecular cloning and characterization of angiopoietin-like protein-8 gene in pigs and its tissue-specific expression in different animals
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Study of serum betatrophin level as a biochemical marker in patients with type 2 diabetes mellitus
Naglaa Abbas, MEGAHED MOH ABOUELMAGD, Hamdy Fouad Ali Marzouk, Mona Elghaba · 2022 · International Journal of Medical Arts
The predictive diagnosis for ANGPTL8 level in women with T2DM
Aws Safaa Fadhel, Manal F. Al-Khakani · 2022 · International Journal of Health Sciences
Impact of a post-lifestyle modification program in circulating angiopoietin-like proteins in Arab adolescents
Mona M. Alenazi, Shaun Sabico, Abdullah M. Alnaami, Kaiser Wani, Syed Danish Hussain, Nasser M. Al‐Daghri · 2024 · Journal of King Saud University - Science
Clinical Value of Circulating Angiopoietin-like Protein 8/Betatrophin Levels in Patients with Acute Pancreatitis
Perihan Özkan Gümüşkaya, Emine Yıldırım, Özgür Altun, Hafize Uzun · 2025 · Medicina
Impact of Tumor Necrosis Factor Antagonist Therapy on Circulating Angiopoietin-like Protein 8 (ANGPTL8) Levels in Crohn’s Disease—A Prospective Multi-Center Study
Mohammad Shehab, Sharifa Al-Fajri, Ahmed Alanqar, Mohammad Alborom, Fatema Alrashed, Fatemah Alshammaa, Ahmad Alfadhli, Sriraman Devarajan, Irina Al‐Khairi, Preethi Cherian et al. · 2025 · Journal of Clinical Medicine
Additional file 1 of Circulating ANGPTL8 levels and risk of kidney function decline: Results from the 4C Study
Zou, Huajie, Xu, Yongping, Meng, Xiaoyu, Li, Danpei, Xi Chen, Tingting Du, Yan Yang, Chen, Yong, 邵诗颖, Yuan, Gang et al. · 2021 · Figshare
Evaluation of Serum Betatrophin Levels in Normal-Weight and Overweight Adolescents with Polycystic Ovary Syndrome
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