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Hemoglobin AIc as an indicator of the degree of glucose intolerance in diabetes
Abstract
Hemoglobin AIc concentration, fasting blood sugar, response to an oral glucose tolerance test, and skeletal muscle capillary basement membrane thickness were measured in diabetic patients. Hemoglobin AIc concentration correlates with both response to a glucose tolerance test (r = 0.82, p < 0.001) and fasting blood sugar (r = 0.62, p < 0.001). The correlation of hemoglobin AIc concentration with glucose tolerance is independent of fasting blood sugar concentration (partial r = 0.61, p < 0.005), whereas that of hemoglobin AIc with fasting blood sugar probably reflects the relationship between fasting blood sugar levels and glucose tolerance (partial r = 0.22, p < 0.05). Hemoglobin AIc levels do not correlate with basement membrane thickness (r = 0.15, p < 0.05).
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Citations
Cited by
American Diabetes Association (2003) · Diabetes Care · doi:10.2337/diacare.26.2007.s106 · Cited by 988
Goldstein, D. E., Little, R. R., Lorenz, R. A., Malone, J. I., Nathan, D., Peterson, C. M., & Sacks, D. B. (2004) · Diabetes Care · doi:10.2337/diacare.27.7.1761 · Cited by 625
Self-citationRelationship between glycated haemoglobin levels and mean glucose levels over time
Nathan, D. M., Turgeon, H., & Regan, S. (2007) · Diabetologia · doi:10.1007/s00125-007-0803-0 · Cited by 517
Relation of diabetic control to development of microvascular complications
Tchobroutsky, G. (1978) · Diabetologia · doi:10.1007/bf00421230 · Cited by 425
Maternal postprandial glucose levels and infant birth weight: the diabetes in early pregnancy study
Jovanovic-Peterson, L., Peterson, C. M., Reed, G. F., Metzger, B. E., Mills, J. L., Knopp, R. H., & Aarons, J. H. (1991) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(91)90637-7 · Cited by 411
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Metadata
- Authors
- Koenig, R. J., Peterson, C. M., Kilo, C., Cerami, A., & Williamson, J. R.
- Venue
- Diabetes
- Publisher
- American Diabetes Association
- Published
- 1976-03-01
- Volume
- 25
- Issue
- 3
- Pages
- 230-232
- ISSN
- 0012-1797 (ISSN-L)
- 1939-327X
- OpenAlex
- W2159565889
- Cited by
- 237
- References
- 0
- FWCI
- 19.53
- Type
- journal article
- Language
- en
- Open access
- closed
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- Koenig, R. J., Peterson, C. M., Kilo, C., Cerami, A., & Williamson, J. R. (1976). Hemoglobin AIc as an indicator of the degree of glucose intolerance in diabetes. Diabetes. https://doi.org/10.2337/diab.25.3.230
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