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Effects of a Traditional Lifestyle on Obesity in Pima Indians
Abstract
OBJECTIVE: The Pima Indians of Arizona have the highest reported prevalences of obesity and non-insulin-dependent diabetes mellitus (NIDDM). In parallel with abrupt changes in lifestyle, these prevalences in Arizona Pimas have increased to epidemic proportions during the past decades. To assess the possible impact of the environment on the prevalences of obesity and NIDDM, data were collected on members of a population of Pima ancestry (separation 700–1,000 years ago) living in a remote mountainous location in northwestern Mexico, with a lifestyle contrasting markedly with that in Arizona. RESEARCH DESIGN AND METHODS: Pima heritage was established by history and by use of Pima language. Measurements of weight, height, body fat (bio-impedance), blood pressure, plasma levels of glucose, cholesterol, and HbA1c were obtained in 19 women (36 ±13 years of age) and 16 men (48 ±14 years of age) and compared with sex-, age- and diabetes status-matched Pimas living in Arizona (10 Arizona Pimas for each Mexican Pima). RESULTS: Mexican Pimas were lighter (64.2 ± 13.9 vs. 90.2 ± 21.1 kg, P < 0.0001; means ± SD) and shorter (160 ± 8 vs. 164 ± 8 cm, P < 0.01) with lower body mass indexes (24.9 ± 4.0 vs. 33.4 ± 7.5 kg/m2, P < 0.0001) and lower plasma total cholesterol levels (146 ± 30 vs. 174 ± 31 mg/dl, P < 0.0001) than Arizona Pimas. Only two women (11%) and one man (6%) had NIDDM, contrasting with the expected prevalences of 37 and 54% in female and male Arizona Pimas, respectively. CONCLUSIONS: This preliminary investigation shows that obesity, and perhaps NIDDM, is less prevalent among people of Pima heritage living a “traditional” lifestyle than among Pimas living in an “affluent” environment. These findings suggest that, despite a similar potential genetic predisposition to these conditions, a traditional lifestyle, characterized by a diet including less animal fat and more complex carbohydrates and by greater energy expenditure in physical labor, may protect against the development of cardiovascular disease risk factors, obesity, and NIDDM.
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“In contrast with the U.S. Pima Indians, they have experienced relatively little recent change in environmental conditions (9,10).”
From Effects of Traditional and Western Environments on Prevalence of Type 2 Diabetes in Pima Indians in Mexico and the U.S. (2006) · cites this paper as [9]
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Metadata
- Authors
- Ravussin, E., Valencia, M. E., Esparza, J., Bennett, P. H., & Schulz, L. O.
- Affiliations
- Clinical Diabetes and Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health Phoenix, Arizona
- Centro de Investigación en Alimentación y Desarrollo (MX)
- Nutrition Division Centro de Investigacion en Alimentacion y Desarrollo Sonora, Mexico
- National Institutes of Health (US)
- University of Wisconsin–Milwaukee (US)
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 1994-09-01
- Volume
- 17
- Issue
- 9
- Pages
- 1067-1074
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2069685883
- Cited by
- 376
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 5 · 2020: 8 · 2019: 6 · 2018: 5 · 2017: 9 · 2016: 15 · 2015: 11 · 2014: 10 · 2013: 19 · 2012: 18
- FWCI
- 20.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Indigenous Health and Education
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- Pima Indians, obesity, type 2 diabetes, traditional way of life, lifestyle modification, body mass index, serum cholesterol, HbA1c, physical activity, energy expenditure, cardiovascular risk factors, genetic susceptibility, diet and obesity, blood pressure, glucose concentration
- MeSH terms
- Adolescent, Adult, Aged, Arizona, Blood Glucose, Body Composition, Cholesterol, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diet, Female, Glycated Hemoglobin, Humans, Indians, North American, Life Style, Male, Mexico, Middle Aged, Obesity, Exercise, Causality, Prevalence, Diabetes Complications
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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