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Cited by 438

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Effect of Protein Ingestion on the Glucose and Insulin Response to a Standardized Oral Glucose Load

Nuttall, Frank Q, Mooradian, Arshag D, Gannon, Mary C, Billington, Charles, Krezowski, Phillip·1984·Diabetes Care
DOI 10.2337/diacare.7.5.465
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Abstract

Type II diabetic subjects were given 50 g protein, 50 g glucose, or 50 g glucose with 50 g protein as a single meal in random sequence. The plasma glucose and insulin response was determined over the subsequent 5 h. The plasma glucose area above the baseline following a glucose meal was reduced 34% when protein was given with the glucose. When protein was given alone, the glucose concentration remained stable for 2 h and then declined. The insulin area following glucose was only modestly greater than with a protein meal (97 ± 35, 83 ± 19 µU · h/ml, respectively). When glucose was given with protein, the mean insulin area was considerably greater than when glucose or protein was given alone (247 ± 33 µU · h/ml). When various amounts of protein were given with 50 g glucose, the insulin area response was essentially first order. Subsequently, subjects were given 50 g glucose or 50 g glucose with 50 g protein as two meals 4 h apart in random sequence. The insulin areas were not significantly different for each meal but were higher when protein + glucose was given. After the second glucose meal the plasma glucose area was 33% less than after the first meal. Following the second glucose + protein meal the plasma glucose area was markedly reduced, being only 7% as large as after the first meal. These data indicate that protein given with glucose will increase insulin secretion and reduce the plasma glucose rise in at least some type II diabetic persons.

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Metadata

Authors
Nuttall, F. Q., Mooradian, A. D., Gannon, M. C., Billington, C., & Krezowski, P.
Venue
Diabetes Care
Publisher
American Diabetes Association
Published
1984-09-01
Volume
7
Issue
5
Pages
465-470
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
DOI
10.2337/diacare.7.5.465
OpenAlex
W2033352867
Cited by
438
References
23
FWCI
5.29
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Effect of Protein Ingestion on the Glucose and Insulin Response to a Standardized Oral Glucose Load. https://app.cochat.ai/papers/10.2337/diacare.7.5.465
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Nuttall, F. Q., Mooradian, A. D., Gannon, M. C., Billington, C., & Krezowski, P. (1984). Effect of Protein Ingestion on the Glucose and Insulin Response to a Standardized Oral Glucose Load. Diabetes Care. https://doi.org/10.2337/diacare.7.5.465

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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