Cited by 35Contact Dermatitis and AllergiesAllergic Rhinitis and SensitizationFood Allergy and Anaphylaxis Research

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Does Allergen-specific Immunotherapy Induce Contact Allergy to Aluminium?

Open access
Netterlid, E, Hindsén, M, Siemund, I, Björk, J, Werner, S, Jacobsson, H, Güner, N, Bruze, M·2013·Acta Dermato Venereologica

Abstract

Persistent, itching nodules have been reported to appear at the injection site after allergen-specific immuno-therapy with aluminium-precipitated antigen extract, occasionally in conjunction with contact allergy to aluminium. This study aimed to quantify the development of contact allergy to aluminium during allergen-specific immunotherapy. A randomized, controlled, single-blind multicentre study of children and adults entering allergen-specific immunotherapy was performed using questionnaires and patch-testing. A total of 205 individuals completed the study. In the 3 study groups all subjects tested negative to aluminium before allergen-specific immunotherapy and 4 tested positive after therapy. In the control group 4 participants tested positive to aluminium. Six out of 8 who tested positive also had atopic dermatitis. Positive test results were found in 5/78 children and 3/127 adults. Allergen-specific immunotherapy was not shown to be a risk factor for contact allergy to aluminium. Among those who did develop aluminium allergy, children and those with atopic dermatitis were more highly represented.

Overview

Integrity signals

Registry

Crossref · 10.2340/00015555-1409

Cites

28 of 28 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

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  • Contact allergy to Al has been reported as an aberrant immune response in those having atopic dermatitis.

    “Contact allergy to Al has been reported as an aberrant immune response in those having atopic dermatitis (Netterlid et al., 2013).”

    From Aluminium toxicosis: a review of toxic actions and effects (2019) · cites this paper as Netterlid et al., 2013

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Metadata

Authors
Netterlid, E., Hindsén, M., Siemund, I., Björk, J., Werner, S., Jacobsson, H., Güner, N., & Bruze, M.
Affiliations
  • Lund University (SE)
  • Skåne University Hospital (SE)
Venue
Acta Dermato Venereologica
Published
2013
Volume
93
Issue
1
Pages
50-56
ISSN
0001-5555 (ISSN-L)
OpenAlex
W2107911772
Cited by
35
References
28
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 3 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 4 · 2015: 3 · 2014: 2 · 2013: 1
FWCI
3.89
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Acta Dermato Venereologica (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Lund University Publications (Lund University) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
  • Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
  • Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Keywords
allergen immunotherapy, patch testing, atopic dermatitis, children, adults
MeSH terms
Adolescent, Adult, Aged, Allergens, Aluminum, Child, Preschool, Dermatitis, Atopic, Dermatitis, Contact, Desensitization, Immunologic, Female, Humans, Male, Middle Aged, Patch Tests, Surveys and Questionnaires, Single-Blind Method, Young Adult

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