Cited by 154melanin and skin pigmentationThyroid Disorders and TreatmentsPhotodynamic Therapy Research Studies

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A possible new incoherent lamp for photodynamic treatment of superficial skin lesions

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Szeimies, R M, Hein, R, Bäumler, W, Heine, A, Landthaler, M·1994·Acta Dermato Venereologica

DOI 10.2340/0001555574120123

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Abstract

An association between vitiligo and autoimmune thyroid disease has previously been suspected. This study was undertaken to determine the frequency and type of thyroid disease in 35 consecutive patients admitted because of vitiligo compared with a matched control group. One or more signs of thyroid disease was demonstrated in 15 out of 35 patients (43%) with vitiligo, as compared to 7 out of 35 (20%) in the matched control group (p = 0.04). Thyroid dysfunction - 6 patients with hyperthyroidism and 2 with hypothyroidism - was found in 8 out of 35 patients, as compared to no patient in the control group (p = 0.003). Nine patients had thyroid autoantibodies, compared to 2 controls, and 6 had an enlarged thyroid gland, compared to 5 subjects in the control group. There appears to be an increased frequency of clinical as well as subclinical thyroid disease in patients with vitiligo. Our findings support the theory of vitiligo being an autoimmune disease and indicate a need for screening vitiligo patients for thyroid disease.

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Research works printed but not linked: 12

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Authors: Szeimies, R. M., Hein, R., Bäumler, W., Heine, A., & Landthaler, M.
Affiliations: Herlev Hospital (DK)
Venue: Acta Dermato Venereologica
Publisher: Medical Journals Sweden AB
Published: 1994-03-01
Volume: 74
Issue: 2
Pages: 117-119
ISSN: 0001-5555 (ISSN-L)
1651-2057
DOI: 10.2340/0001555574120123
OpenAlex: W122435564
Cited by: 154
References: 0
Citations by year: 2024: 2 · 2023: 3 · 2022: 6 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 7 · 2012: 3
FWCI: 2.77
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc
Locations: Acta Dermato Venereologica (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Photodynamic Therapy Research Studies
Keywords: vitiligo, autoimmune thyroid disease, thyroid dysfunction, hyperthyroidism, hypothyroidism, thyroid autoantibodies, thyroid screening, photodynamic therapy, superficial skin lesions
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Autoantibodies, Autoimmune Diseases, Female, Goiter, Graves Disease, Humans, Iodide Peroxidase, Male, Middle Aged, Thyroid Diseases, Thyroiditis, Autoimmune, Vitiligo

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A possible new incoherent lamp for photodynamic treatment of superficial skin lesions

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