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A possible new incoherent lamp for photodynamic treatment of superficial skin lesions
Open accessAbstract
An association between vitiligo and autoimmune thyroid disease has previously been suspected. This study was undertaken to determine the frequency and type of thyroid disease in 35 consecutive patients admitted because of vitiligo compared with a matched control group. One or more signs of thyroid disease was demonstrated in 15 out of 35 patients (43%) with vitiligo, as compared to 7 out of 35 (20%) in the matched control group (p = 0.04). Thyroid dysfunction - 6 patients with hyperthyroidism and 2 with hypothyroidism - was found in 8 out of 35 patients, as compared to no patient in the control group (p = 0.003). Nine patients had thyroid autoantibodies, compared to 2 controls, and 6 had an enlarged thyroid gland, compared to 5 subjects in the control group. There appears to be an increased frequency of clinical as well as subclinical thyroid disease in patients with vitiligo. Our findings support the theory of vitiligo being an autoimmune disease and indicate a need for screening vitiligo patients for thyroid disease.
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“Coherence appears to be lost within <1 mm of penetration into the skin [27].”
From Photodynamic Therapy for Non-Melanoma Skin Cancers (2016) · cites this paper as [27]
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Photodynamic therapy in dermatology
Kalka, K., Merk, H. F., & Mukhtar, H. (2000) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(00)90209-3 · Cited by 515
Evidence for an Autoimmune Pathogenesis of Vitiligo
Ongenae, K., van Geel, N., & Naeyaert, J. M. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00023.x · Cited by 437
Cutaneous Manifestations of Endocrine Disorders
Jabbour, S. A. (2003) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200304050-00003 · Cited by 231
Photodynamic therapy in dermatology: state-of-the-art
Babilas, P., Schreml, S., Landthaler, M., & Szeimies, R. (2010) · Photodermatology Photoimmunology & Photomedicine · doi:10.1111/j.1600-0781.2010.00507.x · Cited by 235
Self-citationPaus, R., Schallreuter, K. U., Bahadoran, P., Picardo, M., Slominski, A. T., Elassiuty, Y. E., Kemp, E. H., Giachino, C., Liu, J. B., Luiten, R. M., et al. (2008) · Experimental Dermatology · doi:10.1111/j.1600-0625.2007.00666_1.x · Cited by 216
Metadata
- Authors
- Szeimies, R. M., Hein, R., Bäumler, W., Heine, A., & Landthaler, M.
- Affiliations
- Herlev Hospital (DK)
- Venue
- Acta Dermato Venereologica
- Publisher
- Medical Journals Sweden AB
- Published
- 1994-03-01
- Volume
- 74
- Issue
- 2
- Pages
- 117-119
- ISSN
- 0001-5555 (ISSN-L)
- 1651-2057
- OpenAlex
- W122435564
- Cited by
- 154
- References
- 0
- Citations by year
- 2024: 2 · 2023: 3 · 2022: 6 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 7 · 2012: 3
- FWCI
- 2.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Acta Dermato Venereologica (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Photodynamic Therapy Research Studies
- Keywords
- vitiligo, autoimmune thyroid disease, thyroid dysfunction, hyperthyroidism, hypothyroidism, thyroid autoantibodies, thyroid screening, photodynamic therapy, superficial skin lesions
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Autoantibodies, Autoimmune Diseases, Female, Goiter, Graves Disease, Humans, Iodide Peroxidase, Male, Middle Aged, Thyroid Diseases, Thyroiditis, Autoimmune, Vitiligo
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