Efficacy of fenbendazole against giardiasis in dogs
Open accessAbstract
Summary: Efficacy of fenbendazole at 2 dosages for treating naturally acquired giardiasis in dogs was assessed. Giardia cysts were not detected in the feces of 6 of 6 group-1 dogs (as determined by use of the zinc sulfate concentration technique) after fenbendazole treatment (50 mg/kg of body weight, po, q 24 h, for 3 doses). Cysts were not detected in the feces of 6 of 6 group-2 dogs after fenbendazole treatment (50 mg/ kg of body weight, po, q 8 h, for 3 days). However, cysts were not detected in the feces of only 1 of 6 group-3 (nontreated control) dogs. Signs of toxicosis were not observed in any dog. These results indicate that the current label dosage (for the treatment of Toxocara canis, Toxascarisleonina, Ancylostoma canmum, Uncinaria stenocephala, Trichuris vulpis, and Taenia pisiformis, but not Giardia spp) of fenbendazole (50 mg/kg, po, q 24 h, for 3 doses) is also effective for treating giardiasis in dogs.
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The benzimidazoles fenbendazole, albendazole, and febantel have been successfully used to treat giardiasis in dogs.
“The benzimidazoles, fenbendazole, albendazole, and febantel (a drug that is metabolized to fenbendazole) have been successfully used to treat giardiasis in dogs.8,10,11,14”
From Evaluation of fenbendazole for treatment of Giardia infection in cats concurrently infected with Cryptosporidium parvum. (2003) · cites this paper as [10]
The Abstract reports successful fenbendazole treatment in dogs, and the Additional information section reports that albendazole removed Giardia cysts from infected dogs. The copy does not address febantel or the claim that it is metabolized to fenbendazole (searched: febantel). No page number was provided for these passages. (LLM, conf=0.88)
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Cites
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Flagged first, then by citations
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Miró, G., Mateo, M., Montoya, A., Vela, E., & Calonge, R. (2007) · Parasitology Research · doi:10.1007/s00436-006-0258-0 · Cited by 77 · see citing works
Efficacy of Giardia vaccination in the treatment of giardiasis in cats
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- Authors
- Barr, S. C., Bowman, D. D., & Heller, R. L.
- Affiliations
- Cornell University (US)
- ORCID
- Bowman, Dwight D.
- Venue
- American Journal of Veterinary Research
- Published
- 1994-07-01
- Volume
- 55
- Issue
- 7
- Pages
- 988-990
- ISSN
- 0002-9645 (ISSN-L)
- OpenAlex
- W4391199360
- Semantic Scholar
- 1660c27cb60a39e445c2ae3a3d5702ac4873cd78
- Cited by
- 55
- References
- 11
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 1 · 2013: 3 · 2012: 1
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Veterinary Research (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Parasitology › Parasitic Infections and Diagnostics
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Health Sciences › Veterinary › Small Animals › Veterinary medicine and infectious diseases
- Keywords
- fenbendazole, canine giardiasis, Giardia, anthelmintic efficacy, dosing regimen, dogs, drug toxicity
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