Cited by 45Occupational and environmental lung diseasesIntraperitoneal and Appendiceal MalignanciesOccupational Health and Global Justice

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

Malignant Mesothelioma: A Clinical Study of 238 Cases

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HABER, Steven E., HABER, Jason M.·2011·Industrial Health

Abstract

Malignant mesothelioma is a diffuse tumor arising in the pleura, peritoneum, or other serosal surface and is closely associated with asbestos exposure. An estimated 2,500 to 3,000 cases are diagnosed each year in the United States. Although there are individual case reports and small series detailing the clinical aspects of mesothelioma, few studies examine a large series of patients with malignant mesothelioma from the clinical perspective. This study reports on the findings of 238 cases of malignant mesothelioma from a private consultative medical practice. Most cases had a history of occupational asbestos exposure. The mean latency was 48.5 yr, with women having a longer latency than men. The mean age at diagnosis was 70. Survival overall was poor (mean 8.8 months), but treatment was beneficial (mean 11.3 versus 6.4 months). Epithelioid histology conferred a survival advantage over sarcomatoid and responded better to treatment. Our data support an inverse relationship between asbestos dose and latency.

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  1. 15) National Occupational Health and Safety Commission (2000, 2001, 2002, 2003, 2004) Australia Mesothelioma Register. The incidence of mesothelioma in Australia; Australian mesothelioma register report, Canberra, ACT.

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Metadata

Authors
HABER, S. E., & HABER, J. M.
Affiliations
The University of Texas MD Anderson Cancer Center (US)
Venue
Industrial Health
Published
2011
Volume
49
Issue
2
Pages
166-172
ISSN
  • 0019-8366 (ISSN-L)
  • 1880-8026
OpenAlex
W2105563627
Cited by
45
References
46
Citations by year
2026: 1 · 2025: 1 · 2024: 4 · 2023: 3 · 2022: 1 · 2021: 1 · 2019: 3 · 2018: 3 · 2017: 4 · 2016: 4 · 2015: 4 · 2014: 4 · 2013: 8 · 2012: 3
FWCI
3.19
Type
journal article
Language
en
Open access
Locations
  • Industrial Health (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Occupational and environmental lung diseases
  • Health Sciences › Medicine › Surgery › Intraperitoneal and Appendiceal Malignancies
  • Social Sciences › Health › Occupational Health and Global Justice
Keywords
malignant mesothelioma, asbestos exposure, occupational exposure, latency, survival, epithelioid histology, sarcomatoid histology, pleural mesothelioma, peritoneal mesothelioma, sex differences
MeSH terms
Adult, Aged, Aged, 80 and over, Environmental Exposure, Female, Humans, Male, Mesothelioma, Middle Aged, Occupational Diseases, Peritoneal Neoplasms, Respiratory Tract Neoplasms, Smoking, Time Factors, United States, Occupational Exposure, Sex Distribution

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