Allergic Rhinitis and Its Impact on Work Productivity in Primary Care Practice and a Comparison with Other Common Diseases: The Cross-sectional Study to Evaluate Work Productivity in Allergic Rhinitis Compared with Other Common Diseases (CAPRI) Study
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Background: Allergic rhinitis (AR) is a highly prevalent allergic disease and also counts among the 10 most frequent reasons for medical consultation. Its impact on quality of life (QoL) and work productivity has been established but comparisons with other diseases are rare in the literature. The aim of this study was to evaluate the impact of AR in health-related QoL (HRQoL) and work productivity in primary care patients, compared with other prevalent diseases such as hypertension, diabetes mellitus (DM) type II, and symptomatic depression. Methods: Six hundred sixteen patients were included in a multicenter cross-sectional observational study. A generic HRQoL questionnaire, 36-item Short Form, and a specific questionnaire, “Work Productivity and Activity Impairment” were handed out to measure QoL and work productivity impact of the diseases. To assess clinical severity with a comparable scale between diseases Clinical Global Impression (CGI) had been used. Results: Symptomatic depression was found to produce the greatest impairment on work productivity with a decrease of 59.5%, with significant differences compared with AR, hypertension, and DM type II (p < 0.05). Symptomatic depression was found to produce the highest negative impact on daily activities with a statistically significant reduction of 59.4% (p < 0.05) compared with AR (26.6% decrease), hypertension (8.8% decrease), and DM (16.7% decrease) patients. Differences between AR and DM or hypertension were also significant (p < 0.05). Restriction on daily activities for AR was 27.8%, which is significantly higher (p < 0.05) than hypertension (19.8% decrease) but not DM (25.7% decrease). Depression had the highest impairment on daily activities (59.4%), compared with the remaining three groups (p < 0.05). Conclusion: AR impairs work productivity in a greater magnitude than hypertension and DM type II.
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Presenteeism is very high in allergic rhinitis patients, surpassing that of other chronic diseases such as diabetes.
“Presenteeism (loss of productivity while in the workplace) is very high in AR patients, surpassing that of other chronic diseases such as diabetes [117].”
From Position Paper on Nasal Obstruction: Evaluation and Treatment (2018) · cites this paper as [117]
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- Authors
- Caballer, B. D. L. H., Rodríguez, M., Fraj, J., Cerecedo, I., Antolín-Amérigo, D., & Colas, C.
- Affiliations
- Instituto Ramón y Cajal de Investigación Sanitaria (ES)
- Hospital Universitario Príncipe de Asturias (ES)
- Instituto de Investigación Sanitaria Aragón (ES)
- Hospital Universitario del Sureste (ES)
- Department of Allergy, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
- Department of Allergy, Hospital Clínico-Instituto de Investigación Sanitaria Aragón, Zaragoza, Spain
- Venue
- American Journal of Rhinology & Allergy
- Publisher
- SAGE Publications
- Published
- 2012-09
- Volume
- 26
- Issue
- 5
- Pages
- 390-394
- ISSN
- 1945-8924 (ISSN-L)
- 1945-8932
- PMC
- PMC3904041
- OpenAlex
- W2314964358
- Cited by
- 106
- References
- 6
- Citations by year
- 2026: 7 · 2025: 9 · 2024: 6 · 2023: 11 · 2022: 8 · 2021: 8 · 2020: 8 · 2019: 6 · 2018: 8 · 2017: 13 · 2016: 7 · 2015: 6 · 2014: 7 · 2013: 2
- FWCI
- 3.54
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- American Journal of Rhinology and Allergy (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- allergic rhinitis, labor productivity, health-related quality of life, activity impairment, depression, hypertension, type 2 diabetes, primary care patients
- MeSH terms
- Adult, Cross-Sectional Studies, Depression, Diabetes Mellitus, Type 2, Efficiency, Female, Rhinitis, Allergic, Seasonal, Humans, Hypertension, Male, Middle Aged, Primary Health Care, Quality of Life, Surveys and Questionnaires, Rhinitis, Allergic, Perennial, Work, Young Adult
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