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Cited by 23Respiratory and Cough-Related ResearchAllergic Rhinitis and SensitizationAsthma and respiratory diseases

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Normal Saline Solution Nasal-Pharyngeal Irrigation Improves Chronic Cough Associated with Allergic Rhinitis

Lin, Lin, Chen, Zhongchun, Cao, Yitan, Sun, Guangbin·2017·American Journal of Rhinology & Allergy
DOI 10.2500/ajra.2017.31.4418
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Abstract

Background Upper airway inflammation is one of the most commonly identified causes of chronic cough, although the underlying mechanism is not clear. This study compared normal saline solution nasal-pharyngeal irrigation (NSNPI) and fluticasone propionate nasal spray (FPNS) treatment for chronic cough associated with allergic rhinitis (AR). Methods Patients with suspected AR to house-dust mite were enrolled, and the symptom of cough was assessed by a cough symptom score and the Leicester Cough Questionnaire, and cough response to capsaicin was evaluated. AR was assessed by using the visual analog scale (VAS) and the Mini Juniper Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ). Mediators, including histamine, leukotriene C4, and prostaglandin D2, and the major basic protein from nasal lavage fluid (NLF) were examined. The patients were treated with NSNPI (the NSNPI group) or FPNS (the FPNS group) for 30 days, after which they were reassessed. Results Forty-five of 50 patients completed this study. The scores of the cough symptom and the Leicester Cough Questionnaire, and the capsaicin cough threshold all improved statistically after NSNPI but did not change after FPNS. There were statistically significant changes in the evaluations of the MiniRQLQ and the mediators, including histamine and leukotriene C4, in the NLF in the NSNPI group. However, significant changes were found in the assessments of VAS, MiniRQLQ, and all above mediators including histamine, leukotrie…

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Crossref · 10.2500/ajra.2017.31.4418

Cites

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Citations

Cites

Show all 41 references

Research works printed but not linked: 7

  1. O'Hara J., 2006, Rhinology, 44, 270
  2. Plevkova J., 2004, J Physiol Pharmacol, 55, 101
  3. Plevkova J., 2005, J Physiol Pharmacol, 56, 185
  4. Lin L., 2014, Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 49, 109
  5. Pecova R., 2005, J Physiol Pharmacol, 56, 171
  6. Chung K.F., 2009, Handb Exp Pharmacol, 1
  7. Holmström M., 1997, Rhinol-ogy, 35, 108

Cited by

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Related

Metadata

Authors
Lin, L., Chen, Z., Cao, Y., & Sun, G.
Affiliations
Fudan University (CN)
Corresponding author
Lin, Lin
ORCID
Venue
American Journal of Rhinology & Allergy
Publisher
SAGE Publications
Published
2017-03
Volume
31
Issue
2
Pages
96-104
ISSN
  • 1945-8924 (ISSN-L)
  • 1945-8932
DOI
10.2500/ajra.2017.31.4418
OpenAlex
W2607924026
Cited by
23
References
41
Citations by year
2026: 2 · 2025: 2 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 1
FWCI
1.81
Type
journal article
Language
en
Open access
closed
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • American Journal of Rhinology and Allergy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory and Cough-Related Research
  • Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Keywords
chronic cough, allergic rhinitis, house dust mite allergy, normal saline irrigation, intranasal corticosteroids, nasal lavage fluid, histamine, leukotriene C4, prostaglandin D2, major basic protein, Leicester Cough Questionnaire
MeSH terms
Fluticasone, Adenoids, Adolescent, Adult, Aged, Animals, Chronic Disease, Cough, Humans, Therapeutic Irrigation, Middle Aged, Paranasal Sinuses, Sodium Chloride, Antigens, Dermatophagoides, Pyroglyphidae, Young Adult, Nasal Sprays, Rhinitis, Allergic

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.