Cited by 5

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Brain gamma rhythm and potential treatment of neurodegenerative disease

Zhao, Jianhua, Du, Ailin, Lu, Chengbiao·2020·Journal of Neurorestoratology

Abstract

In this mini-review, we illustrate the brain network oscillations in different brain areas, including the medial septal diagonal band complex (MSDB) and hippocampus , especially at gamma frequency bands ( γ , 30–80 Hz) and theta frequency bands ( θ , 4–12 Hz), and their induction and modulation by physical stimulation, such as light and sound, and pharmacological stimulation with agents such as agonists of the kainite subunit ionotropic glutamate receptor , metabotropic glutamate receptor , metabotropic cholinergic receptor , and nicotinic cholinergic receptor. Recent findings demonstrate that boosting gamma oscillations in specific brain areas appears to be able to restore cognitive function and reduce relative pathology in neurodegenerative diseases , such as Alzheimer’s disease. Thus, exploration of strategies to enhance or restore impaired gamma oscillations may be a new and effective method to improve the conditions in these devastating diseases.

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Crossref · 10.26599/jnr.2020.9040002

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Research works printed but not linked: 25

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Metadata

Authors
Zhao, J., Du, A., & Lu, C.
Venue
Journal of Neurorestoratology
Publisher
Elsevier BV
Published
2020-03
Volume
8
Issue
1
Pages
26-31
ISSN
2324-2426
Cited by
5
References
4
Language
en

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