AP-1 targets in the brain

Rylski, Marcin

doi:10.2741/1207

Cited by 34Genomics and Chromatin DynamicsNeuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling

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AP-1 targets in the brain

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Rylski, Marcin·2004·Frontiers in Bioscience

DOI 10.2741/1207

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Abstract

Activator protein-1 (AP-1) is a transcription factor involved in many aspects of the brain physiology and pathophysiology. In spite of strong engagement in a transcriptional regulation of the brain gene expression, only a few, if any, downstream AP-1 targets have unequivocally been identified so far. In the review we discuss only the best characterized AP-1 target genes in the brain, and we highlight the shortages of our understanding of AP-1 action in the central nervous system as well as indicate what could be done to ameliorate the situation.

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Authors: Rylski, M.
Affiliations: Instytut Biologii Doświadczalnej im. Marcelego Nenckiego (PL)
Corresponding author: Rylski, Marcin
ORCID: Rylski, Marcin
Venue: Frontiers in Bioscience
Publisher: IMR Press
Published: 2004
Volume: 9
Issue: 1-3
Pages: 8
ISSN: 1093-4715 (ISSN-L)
1093-9946
DOI: 10.2741/1207
OpenAlex: W2067060630
Cited by: 33
References: 98
Citations by year: 2025: 2 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 2 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 1
FWCI: 0.33
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Frontiers in bioscience (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
Keywords: activator protein-1, transcription factors, brain gene expression, central nervous system, transcriptional regulation, neurobiology
MeSH terms: Brain, Gene Expression Regulation, Humans, Transcription Factor AP-1

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