AMPK: Lessons from transgenic and knockout animals

Viollet, Benoit·2009·Frontiers in bioscience

Cited by (315)

Items 101–200 of 315

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  2. Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis
    Markus Daniel Lacher, Roxana Pincheira, Zhou Zhu, Blanca Camoretti-Mercado, Mary R. Matli, Robert S. Warren, Ariel Fernando Castro · 2010 · Oncogene
  3. Augmenting energy expenditure by mitochondrial uncoupling: A role of AMP-activated protein kinase
    Klaus, Susanne, Keipert, Susanne, Rossmeisl, Martin, Kopecky, Jan · 2012 · Genes & Nutrition
  4. Genetically Encoded ATP Biosensors for Direct Monitoring of Cellular ATP Dynamics
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  5. AMPK regulates macrophage polarization in adipose tissue inflammation and NASH
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  6. Circadian Rhythms in Liver Physiology and Liver Diseases
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  7. Effects of activation of AMPK on human breast cancer cell lines with different genetic backgrounds
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  8. AMPK 2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis
    Kathryn N. Phoenix, Charan Kumar V. Devarakonda, M. M. Fox, L. E. Stevens, Kevin P. Claffey · 2012 · Genes & Cancer
  9. Apigenin and luteolin display differential hypocholesterolemic mechanisms in mice fed a high-fat diet
    Tsz Yan Wong, Yan Qin Tan, Shumei Lin, Lai Kwok Leung · 2017 · Biomedicine & Pharmacotherapy
  10. Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal
    Julia K. Brynildsen, Bridgin G. Lee, Isaac J. Perron, Sunghee Jin, Sangwon F. Kim, Julie A. Blendy · 2018 · Proceedings of the National Academy of Sciences
  11. Hepatic p38α regulates gluconeogenesis by suppressing AMPK
    Yanyan Jing, Wei Liu, Hongchao Cao, Duo Zhang, Xuan Yao, Shengjie Zhang, Hongfeng Xia, Dan Li, Yucheng Wang, Jun Yan et al. · 2015 · Journal of Hepatology
  12. AMP-dependent Kinase Inhibits Oxidative Stress-induced Caveolin-1 Phosphorylation and Endocytosis by Suppressing the Dissociation between c-Abl and Prdx1 Proteins in Endothelial Cells
    Kimio Takeuchi, Yuki Morizane, Cynthia Kamami-Levy, Jun Suzuki, Maki Kayama, Wenyi Cai, Joan W. Miller, Demetrios G. Vavvas · 2013 · Journal of Biological Chemistry
  13. The Outcome of Renal Ischemia-Reperfusion Injury Is Unchanged in AMPK-β1 Deficient Mice
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  14. Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage
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  15. A Tbc1d1 Ser231Ala-knockin mutation partially impairs AICAR- but not exercise-induced muscle glucose uptake in mice
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  16. Lycium ruthenicum extract alleviates high-fat diet-induced nonalcoholic fatty liver disease via enhancing the AMPK signaling pathway
    Jiayao Lin, Yu Zhang, XINQING WANG, Wenwen Wang · 2015 · Molecular Medicine Reports
  17. AMP-Activated Protein Kinase (AMPK)-Dependent Regulation of Renal Transport
    Philipp Glosse, Michael Föller · 2018 · International Journal of Molecular Sciences
  18. Impaired Expression of Uncoupling Protein 2 Causes Defective Postischemic Angiogenesis in Mice Deficient in AMP-Activated Protein Kinase α Subunits
    Xu, Ming-Jiang, Song, Ping, Shirwany, Najeeb, Liang, Bin, Xing, Junjie, Viollet, Benoit, Wang, Xian, Zhu, Yi, Zou, Ming-Hui · 2011 · Arteriosclerosis Thrombosis and Vascular Biology
  19. 5′‐AMP‐activated protein kinase activity is elevated early during primary brain tumor development in the rat
    Taichang Jang, Joy M. Calaoagan, Eunice E. Kwon, Steven J. Samuelsson, Lawrence David Recht, Keith R. Laderoute · 2010 · International Journal of Cancer
  20. Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
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  21. Targeting the AMPK/Nrf2 Pathway: A Novel Therapeutic Approach for Acute Lung Injury
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  24. Glucagon-Like Peptide 1 (GLP-1) Can Reverse AMP-Activated Protein Kinase (AMPK) and S6 Kinase (P70S6K) Activities Induced by Fluctuations in Glucose Levels in Hypothalamic Areas Involved in Feeding Behaviour
    Verónica Hurtado-Carneiro, Carmen Sanz, Isabel Roncero, Patricia Vázquez, Enrique Blázquez, Elvira Álvarez · 2012 · Molecular Neurobiology
  25. AMP Activated Protein Kinase Is Indispensable for Myocardial Adaptation to Caloric Restriction in Mice
    Kai Chen, Satoru Kobayashi, Xianmin Xu, Benoı̂t Viollet, Qiangrong Liang · 2013 · PLoS ONE
  26. Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells
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  27. AMPK in Lymphocyte Metabolism and Function
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  29. AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation
    Wilfred Lieberthal, Leiqing Zhang, Vimal A. Patel, Jerrold S. Levine · 2011 · American Journal of Physiology-Renal Physiology
  30. NPFR regulates the synthesis and metabolism of lipids and glycogen via AMPK: Novel targets for efficient corn borer management
    Jiajia Zhao, Shuo Yan, Mingshan Li, Lina Sun, Min Dong, Meizhen Yin, Jie Shen, Zhangwu Zhao · 2023 · International Journal of Biological Macromolecules
  31. AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival
    Kurt W. Fisher, Binita Das, Hyun Seok Kim, Beth K. Neilsen, Drew Gehring, Deandra R. Smith, Diane L. Costanzo-Garvey, Mario R. Fernandez, Michael G. Brattain, David L. Kelly et al. · 2015 · Molecular and Cellular Biology
  32. Role of the α2 subunit of AMP-activated protein kinase and its nuclear localization in mitochondria and energy metabolism-related gene expressions in C2C12 cells
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  33. Maternal High Fat Diet Programs Male Mice Offspring Hyperphagia and Obesity: Mechanism of Increased Appetite Neurons via Altered Neurogenic Factors and Nutrient Sensor AMPK
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  34. Hepatic rRNA Transcription Regulates High-Fat-Diet-Induced Obesity
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  35. Sex-Specific Regulation of AMP-Activated Protein Kinase (AMPK) in the Pacific Oyster Crassostrea gigas1
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  36. Impact of Metformin and Compound C on NIS Expression and Iodine Uptake In Vitro and In Vivo: A Role for CRE in AMPK Modulation of Thyroid Function
    Randa M. Abdulrahman, Mariëtte R. Boon, Hetty C. M. Sips, Bruno Guigas, Patrick C.N. Rensen, Johannes W. A. Smit, Guido C. Hovens · 2013 · Thyroid
  37. Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome
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  38. The Role of AMPK Pathway in Neuroprotection
    Lei Xu, John D. Ash · 2015 · Advances in experimental medicine and biology
  39. Consensus Scoring Approach To Identify the Inhibitors of AMP-Activated Protein Kinase α2 with Virtual Screening
    Hwangseo Park, Jae-Won Eom, Yang Hee Kim · 2014 · Journal of Chemical Information and Modeling
  40. The Last Enzyme of the De Novo Purine Synthesis Pathway 5-aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) Plays a Central Role in Insulin Signaling and the Golgi/Endosomes Protein Network*
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  41. ORM Promotes Skeletal Muscle Glycogen Accumulation via CCR5-Activated AMPK Pathway in Mice
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  42. AMPKα2 reduces renal epithelial transdifferentiation and inflammation after injury through interaction with CK2β
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  43. Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming
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  44. Rapid metabolic reprogramming mediated by the AMP-activated protein kinase during the lytic cycle of Toxoplasma gondii
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  45. AMPK and the Challenge of Treating Hypoxic Pulmonary Hypertension
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  47. HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models
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  48. Liquiritin Attenuates Pathological Cardiac Hypertrophy by Activating the PKA/LKB1/AMPK Pathway
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  49. FAM3A maintains metabolic homeostasis by interacting with F1-ATP synthase to regulate the activity and assembly of ATP synthase
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  50. In vivo stimulation of AMP-activated protein kinase enhanced tubuloglomerular feedback but reduced tubular sodium transport during high dietary NaCl intake
    Dan Yang Huang, Huanhuan Gao, Krishna Murthy Boini, Hartmut Oßwald, Bernd Nürnberg, Florian J.W. Lang · 2010 · Pflügers Archiv - European Journal of Physiology
  51. TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling
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  52. Mitochondria transplantation alleviates cardiomyocytes apoptosis through inhibiting AMPKα‐mTOR mediated excessive autophagy
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  53. Upregulation of Na+/H+ exchanger by the AMP-activated protein kinase
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  54. A novel cardioprotective agent in cardiac transplantation: metformin activation of AMP-activated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection.
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  55. PAS Kinase Is a Nutrient and Energy Sensor in Hypothalamic Areas Required for the Normal Function of AMPK and mTOR/S6K1
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  56. AMP-Activated Protein Kinase Regulates Intraocular Pressure, Extracellular Matrix, and Cytoskeleton in Trabecular Meshwork
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  57. Sustained Activation of AMPK Enhances Differentiation of Human iPSC-Derived Cardiomyocytes via Sirtuin Activation
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  58. AMP-activated Protein Kinase α2 and E2F1 Transcription Factor Mediate Doxorubicin-induced Cytotoxicity by Forming a Positive Signal Loop in Mouse Embryonic Fibroblasts and Non-carcinoma Cells
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  59. Activation of AMPKα2 Is Not Crucial for Mitochondrial Uncoupling-Induced Metabolic Effects but Required to Maintain Skeletal Muscle Integrity
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  60. Hepatocyte-Specific Deletion of AMPKα1 Results in Worse Outcomes in Mice Subjected to Sepsis in a Sex-Specific Manner
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  62. AMPK Knockdown in Placental Labyrinthine Progenitor Cells Results in Restriction of Critical Energy Resources and Terminal Differentiation Failure
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  68. Loss of AMP-activated protein kinase in X-linked adrenoleukodystrophy patient-derived fibroblasts and lymphocytes
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  75. AMP-activated protein kinase deficiency reduces ozone-induced lung injury and oxidative stress in mice
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  76. Knockdown of AMP-activated protein kinase alpha 1 and alpha 2 catalytic subunits.
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  85. AMP-activated protein kinase controls metabolism and heat production during embryonic development in birds
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  90. Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways
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  95. Altered adipocyte progenitor population and adipose-related gene profile in adipose tissue by long-term high-fat diet in mice
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